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#76 · Emerging 100 · 2026

Basis Set Ventures

www.basisset.ventures · Menlo Park, California

“The best way to find and support AI companies is to be one ourselves. We back independent thinkers building real systems before consensus forms, partnering as radical learning partners from day one.”

$250K – $3M
Check Size
Leads
Lead Tendency
$750M
AUM
~2 Weeks
Timeline
01Investment Thesis

The best way to find and support AI companies is to be one ourselves. We back independent thinkers building real systems before consensus forms, partnering as radical learning partners from day one.

Exclusion Criteria

Consensus-driven founders, non-technical teams, founders seeking validation over partnership

02Investment Team
DL
Dr. Lan Xuezhao
Founder & General Partner
RW
Rachel Wong
CTO & Partner
JM
John Mannes
Venture Partner
P
Pascal
AI Partner
LC
Lisa Chen
Operations Manager
WK
Wilson Kyi
Partner
JL
Jennifer Lee
General Counsel & Operating Partner
JM
JB Michel
Venture Partner
03F4 Research Brief

Basis Set Ventures Research

Investment Thesis

Basis Set Ventures is an AI-native venture fund that uses psychometric and quantitative data analysis to identify exceptional founders and support early-stage AI companies. Since inception in 2017, the firm operates from the thesis that the best way to find and support AI companies is to be one themselves. They employ their own proprietary machine learning stack, including foundation models and proprietary tools (Parasail, Tigris, Spice AI, and Simular) to identify founder patterns that correlate with outlier outcomes.

The firm believes in backing "independent thinkers" and "ground truth" seekers—founders moving with maximum velocity before consensus forms. They explicitly avoid consensus-driven investing and prioritize radical honesty, acting as learning partners rather than validators.

Sector Focus

Basis Set has broad sector coverage organized into four primary investment pillars:

  1. Autonomous Systems & Robotics: Manufacturing robots (Path Robotics), agricultural automation (Farmwise), autonomous mobility (Nuro), AI-first autonomy products
  2. Scalable Infrastructure & AI Systems: LLM infrastructure, foundation models (Cusp), AI memory systems (Mem0), GPU infrastructure (Parasail), database infrastructure (Tigris, FerretDB), nature-inspired AI (Sakana)
  3. Intelligent Collaboration Tools: Design and creative tools (OpenArt, Vizcom, Beeble), compliance and regulatory AI (Norm, Drata), HR automation (Workstream), sales automation (Momentum)
  4. Automated Workflows: Supply chain automation (Quince, Trendsi), real estate operations (Banner, Ergeon), senior care (Seen Health), payments infrastructure (Slope)

The portfolio clearly emphasizes AI-native companies across B2B SaaS, infrastructure, enterprise automation, and emerging categories like "infrastructure-first consumer" companies.

Stage Focus

Basis Set explicitly targets early-stage companies from pre-seed through Series A, with selective follow-ons in Series B. The firm believes in backing founders at the "earliest moment when there is nothing but a stubborn belief."

Check Size and Investment Activity

Typical investment range: $2M-$3M for seed rounds, with pre-seed investments around $250K-$500K.

Recent activity (2025-2026):

  • January 2026: Series A investment in OpenArt
  • December 2025: Series A investment in DataLane
  • Fund IV ($250M) announced January 26, 2026, actively deploying
  • 98 total portfolio investments as of December 2025
  • 5 new investments in last 12 months

The firm maintains 50% reserves for follow-on investments.

Fund Status

Fund IV: $250M announced January 26, 2026

  • Actively deploying
  • Positioned to support founders building "real AI systems"
  • Built on 9+ years of AI-native investing experience

Key Team

Leadership:

  • Dr. Lan Xuezhao (Founder & General Partner)
  • Rachel Wong (CTO & Partner) - deep technical expertise
  • John Mannes (Partner)
  • Pascal (AI Partner)
  • Chang Xu (Partner)
  • Wilson Kyi (Partner)
  • Jennifer Lee (General Counsel & Partner)

Support: Multiple venture partners, technical advisors, and staff engineers. The firm operates a "24/7 founder concierge team."

Decision Process

Partnership-based approach with deep technical engagement. Investment committees include the full partnership, technical team members, and subject-matter experts. The firm positions itself as first customer, bug reporter, recruiter, and strategic partner from day one.

Geographic Focus

Primary: San Francisco Bay Area, US Secondary: East Coast (NYC area), Asia (selective sectors) Headquarters: Menlo Park, California

Notable Portfolio Companies

Recent (2024-2026):

  • OpenArt (Series A, Jan 2026) - creative AI platform
  • DataLane (Series A, Dec 2025) - SMB revenue growth platform
  • Seen Health (2024) - full-stack senior care
  • Sakana AI - nature-inspired AI research lab
  • Cusp - molecular and materials discovery foundation models

Established:

  • Quince (since 2019) - supply chain automation
  • Path Robotics (since 2018) - autonomous welding/manufacturing
  • Rasa - conversational AI infrastructure
  • Slope - B2B payments + AI underwriting
  • Farmwise - autonomous agricultural weeding
  • Drata - compliance automation

Portfolio Characteristics

The 98-company portfolio emphasizes:

  • AI infrastructure and tools (Parasail, Tigris, Spice, FerretDB, Rasa, Mem0, Simular)
  • Autonomous systems (robotics, mobility, agricultural automation)
  • Enterprise automation (HR, payroll, compliance, sales workflows)
  • Creative and design tools powered by AI (OpenArt, Vizcom, Beeble)
  • Domain-specific AI (healthcare, real estate, supply chain, payments)

Founder Psychology & Selection

Basis Set uses psychometric analysis and founder-matching algorithms to identify patterns correlating with outlier success. They back founders who:

  • Move toward ground truth with maximum velocity
  • Think independently before consensus forms
  • Build "real systems" with operational complexity
  • Seek radical honesty and partnership, not validation
  • Have strong technical foundations

Competitive Advantages

  1. AI-native from 2017 - Nearly 10 years of AI investing expertise
  2. Quantitative founder selection - Proprietary psychometric analysis
  3. Operational depth - Team includes CTO, staff engineers, technical advisors
  4. Portfolio infrastructure - Proprietary tools founders can leverage (Parasail, Tigris, Spice)
  5. Long-term commitment - "We commit for the long haul, rapidly iterate with you"
  6. Thought leadership - Regular research and perspectives on emerging trends

Founder Testimonials

  • "Basis Set is an extension of my family, of my team. It's been amazing to work with them. It feels like a real, true partnership." - Jenny, Co-founder & CEO (Ergeon)
  • "Working with Basis Set is incredible. They're the first people I call anytime I have a question. They're down to earth and great to work with." - Andy, Co-founder & CEO (Path Robotics)
  • "It's really like a family, people that I can trust. I know when things are down, they are my first call." - Desmond, Co-founder & CEO (Workstream)

Recent Insights

Basis Set publishes research and thought leadership including:

  • "Agents Broke Our Old Infrastructure. Now We Get to Rebuild It" (Jan 2026)
  • "The New Moat is the Method" (Nov 2025)
  • "Beyond B2C: The Rise of Infrastructure-First Consumer Companies" (Jan 2025)
  • Quantitative research on emerging sectors (trucking, maritime, agriculture, real estate)
  • Founder psychology research: "Can Large Language Models predict founder success?"

Summary

Basis Set Ventures is a sophisticated, AI-native seed and Series A investor with a 9+ year track record and $250M+ under management. They combine quantitative founder selection with deep technical engagement, operating more like founder operators than traditional VCs. The firm backs independent technical founders building autonomous systems, AI infrastructure, and enterprise automation at the earliest stages, maintaining long-term partnership commitments and 50% reserve capital for follow-ons.

04Selected Portfolio
AgTech & Agriculture
Farmwise
Biotech & Life Sciences
Neion Bio
Developer Tools & Infrastructure
Mem0·Tigris Data
E-commerce & Marketplaces
DataLane·Quince·Daydream
Enterprise Software
Path Robotics·Sakana AI·Rasa·Drata·Vizcom·Spice AI·Norm·PgDog·Reflow·Entire·Quill Notes
Fintech & Payments
Slope
Healthcare & Digital Health
Seen Health·Basata
HR Tech & Future of Work
Workstream
Manufacturing & Industrial
Ergeon·Neion
Media & Entertainment
OpenArt
Security & Cybersecurity
Clearly AI
Other
Cusp·Parasail·Simular
Open the full portfolio→
05Recent Updates

Fresh signals from public announcements, essays, and portfolio activity.

See full activity (24) →
Portfolio company Entendre, an AI accounting agent maker for crypto and fintech finance operations, was acquired by MoonPay.
EXIT·basisset.com
JUN 22, 2026
Backed PgDog's $5.5M seed round for Postgres connection pooling and sharding.
INVESTMENT·basisset.com
JUN 10, 2026
Backed Basata's $21M Series A to automate healthcare administrative workflows.
INVESTMENT·basisset.com
MAY 8, 2026
Launched the Basis Set AI Fellowship program.
NEWS·basisset.com
APR 25, 2026
Published perspective on open source agent infrastructure and the competitive dynamics shaping the stack.
ESSAY·basisset.com
APR 23, 2026
06Frequent co-investors
GC
GGV Capital
Both backed 2 of the same companies
Drata, Quince
IG
ICONIQ Growth
Both backed 2 of the same companies
Drata, Quince
IV
Index Ventures
Both backed 2 of the same companies
Vizcom, Daydream
NC
Notable Capital
Both backed 2 of the same companies
Drata, Quince
OC
Operator Collective
Both backed 2 of the same companies
DataLane, Workstream
Find the investors for your round→
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LV
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SV
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Quick Reference
Check Size
$250K – $3M
Stages
Pre-Seed · Seed · Series A
AUM
$750M
Decision
Partnership · ~2 Weeks
Warm Intro
Not Required
Involvement
Board Seat
Location
Menlo Park, California
Sector Focus
Biotech & Life SciencesRobotics & AutomationEnterprise SoftwareHR Tech & Future Of WorkDeveloper Tools & InfrastructureSecurity & CybersecurityHealthcare & Digital Health
Models
B2B SaaSAI InfrastructureRoboticsEnterprise Automation
Technology
AI/MLLLMAutonomy
See all Biotech & Life Sciences investors →See all Robotics & Automation investors →See all Enterprise Software investors →
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Focus Areas
Biotech & Life SciencesRobotics & AutomationEnterprise SoftwareHR Tech & Future Of WorkDeveloper Tools & InfrastructureSecurity & CybersecurityHealthcare & Digital Health

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F4 Intelligence Report · Last Researched August 12, 2026F4 Research Engine