Mayfield Fund Research
Investment Thesis
Mayfield Fund is a distinguished venture capital firm founded in 1969 with direct ties to Fairchild Semiconductor founders, making it one of Silicon Valley's original venture funds. The firm has evolved to focus on "Collaborative Intelligence" and "AI Teammates," emphasizing human-AI partnership models. Mayfield invests in founders building AI-first startups and companies leveraging artificial intelligence to create next-generation solutions across enterprise, healthcare, semiconductors, and other sectors.
The firm's core philosophy, "The Mayfield Way," emphasizes a "People First" approach where every investing partner has been a founder themselves, deeply understanding the startup journey. Mayfield serves as an inception-to-iconic partner, positioning themselves as the first investor and last out, providing unwavering support through company lifecycle stages.
Stage Focus
Mayfield primarily invests at inception and early stages:
- Inception/Pre-Seed: Earliest stage companies with breakthrough ideas
- Seed: Companies with initial product and early traction
- Series A: Companies demonstrating product-market fit
- Series B: Selected follow-on investments in portfolio companies
The fund is selective and disciplined, investing in approximately 10 companies per year, committing fresh capital every 3.5-4 years. This measured approach allows deep engagement with each portfolio company.
Check Size
Based on portfolio analysis:
- Typical Range: $200,000 to $20,000,000
- Average Seed Investment: $1,000,000 to $5,000,000
- Series A Participation: $5,000,000 to $20,000,000
- Target Ownership: 15-20% at seed stage
Mayfield follows a disciplined capital deployment model with reserves for follow-on rounds in proven portfolio companies.
Lead Tendency
Mayfield leads the majority of their investments, particularly at earlier stages. As a first-investor firm, they often establish investment theses and bring capital first, though they also co-lead rounds and participate in Series A and beyond alongside peer VCs.
Recent Activity (2025-2026)
Mayfield remains actively deploying from its current $3 billion under management (Mayfield XVI and prior funds). Recent signals include:
- January 2026: Participated in Upscale AI Series A ($20M+), an AI infrastructure company
- November 2025: Investment in Vijil (Trust Infrastructure Platform for Agents)
- 2025: Major focus on AI infrastructure, AI teammates, and enterprise AI applications
- Q4 2025: Strong deal flow in AI/ML, semiconductors, and healthcare tech
The firm is in active deployment mode with particular emphasis on AI-first companies, noting publicly that 2025 represents "the start of a golden era for startups" backed by $307B in dry powder globally.
Portfolio Highlights
Historic Exits and IPOs (120+ IPOs, 225+ M&As):
- HashiCorp: Infrastructure automation, IPO 2021 (NASDAQ: HCP, later acquired by IBM)
- Lyft: Ridesharing, IPO 2019 (NASDAQ: LYFT)
- Poshmark: Social marketplace for fashion, IPO 2021 (NASDAQ: POSH)
- Couchbase: NoSQL database, public company (NASDAQ: BASE)
- Marketo: Marketing automation, acquired by Vista Equity for $4.75B
- Securiti: AI and data controls, acquired for $1.725B (2025)
Active Portfolio (100+ current investments across sectors):
- AI Infrastructure: Gruve.ai, MindsDB, Inception Labs, Alchemy (Web3 Dev), UpscaleAI
- Enterprise AI: DevRev, BigPanda, Scrunch AI, Sema4.ai, Docket AI, DuploCloud
- Healthcare/Biotech: Mammoth Biosciences (CRISPR), Mirvie (maternal health diagnostics), Qventus (healthcare operations automation)
- Semiconductors: Recogni (AI inference), Frore Systems (cooling chips), Alif Semiconductor, Attotude (AI interconnects)
- Infrastructure: Rancher (Kubernetes), Versa Networks (SASE), InfluxDB (timeseries data)
Current Investment Count: 220+ active portfolio companies across AI, enterprise software, semiconductors, healthcare, and emerging tech sectors.
Team & Decision-Making
Investment Team Structure: 9 general partners with complementary expertise across AI, enterprise, semiconductors, and healthcare:
- Navin Chaddha (Managing Partner): AI, enterprise, semiconductors focus—most active investor
- Rajeev Batra: Enterprise software, business networks
- Arvind Gupta: Planetary health and sustainability
- Irving Hsu: AI and enterprise applications
- Tejas Maniar: Enterprise software
- Sri Pangulur: AI and enterprise, billing/monetization focus
- Ursheet Parikh: AI, enterprise, healthcare—broad experience
- Patrick Salyer: AI and enterprise automation
- Vijay Reddy: AI and trust infrastructure
Decision Process: Collective Intelligence Model
- At least two investing partners collaborate on due diligence for each opportunity
- Partners make a recommendation to the entire investment team
- Full team votes on final investment decision
- Promotes thorough evaluation and creates built-in partnership for portfolio support
Decision Timeline: Estimated 2-4 weeks from serious engagement to term sheet for strong candidates, though can vary based on diligence depth.
Founder Preferences
Mayfield looks for:
- Experienced Technical Founders: Founders with domain expertise, often from hyperscalers (Google, Amazon, Meta, Apple) or previous successful startups
- Visionary Thinking: Founders pursuing breakthrough ideas, not incremental innovation
- Collaborative Mindset: Willingness to work closely with investors, accept mentorship, and leverage the Mayfield network
- Founder Stability: Multi-founder teams with complementary skills, clear decision-making
- Market Conviction: Deep understanding of problem space and why their approach will win
- AI-First DNA: For current cohort, founders applying AI as fundamental to their product, not as a feature
Sector & Model Preferences
Primary Sectors (reflected in current portfolio):
- Artificial Intelligence & AI Teammates: Highest priority—building AI copilots, agents, and human-AI collaboration platforms
- Enterprise Software: B2B SaaS, vertical solutions, workflow automation, compliance
- Developer Tools & Infrastructure: DevOps, observability, cloud-native, API platforms
- Semiconductors & Hardware: Edge AI chips, data center interconnects, cooling innovations
- Healthcare & Biotech: Digital health, diagnostics, therapeutics, data-driven medicine
- Security & Compliance: Cybersecurity, data protection, zero-trust architecture
- Data Infrastructure: Databases, timeseries, analytics, ML infrastructure
- Climate & Sustainability: Energy transition, planetary health (secondary focus)
Model Preferences:
- B2B SaaS with clear enterprise value proposition
- Developer-first products with strong community
- Deep tech with defensible IP
- Horizontal platforms serving multiple verticals
- Network effect businesses
- NOT: Consumer apps (very rare), pure marketplaces, gaming, traditional healthcare services
Geographic Focus
Primary: San Francisco Bay Area (especially Menlo Park, Mountain View, Palo Alto) Secondary: New York, Seattle, Los Angeles International: Selective investments in:
- Asia (India, Japan, Singapore for AI and semiconductor talent)
- Europe (limited, strategic partnerships)
- Israel (technology focus)
Mayfield maintains a West Coast bias but has expanded to support portfolio companies' geographic expansion.
Investment Process & Warm Introductions
Warm Introductions: Highly preferred, nearly essential for serious consideration
- Introductions from portfolio founders, limited partners, or trusted advisors carry weight
- Cold outreach is unlikely to receive meaningful attention
- Best path: Portfolio company CEO introduction, or through Mayfield network partners
Typical Investment Process:
- Initial Meeting: Founder pitch, thesis validation (1-2 meetings)
- Deep Dive: Technical due diligence, market validation, team assessment (2-3 weeks)
- Investor Engagement: Navin + partner lead conversations with other investors (1 week)
- Committee Review: Full team discussion and recommendation (2-4 days)
- Term Sheet: 3-5 days to delivery
- Legal & Closing: 2-3 weeks
Total Timeline: 4-8 weeks for well-prepared founders with strong theses.
Value-Add Program
Mayfield provides structured support through their "Value-Add Program" with six key pillars:
- Initial Setup: Curated introductions to legal counsel, office space, HR services, fractional CFO
- Team Building: Recruitment strategy, leadership training, cultural foundation (critical for early hires)
- Product-Market Fit: Access to domain experts, early customer introductions, value proposition refinement
- Story-Market Fit: End-to-end narrative development, vision/mission/positioning, founder positioning
- Early Customer Access: Warm intros to potential design partners and early customers through 8,000-member CXO network
- Follow-On Financing: Introductions to Series A/B investors, strategic positioning for future rounds
Founder Amplification Team: Separate operational team provides:
- Talent recruitment assistance
- Business development support
- Go-to-market strategy
- Customer introductions (3,000+ annually)
- Investor introductions (500+ annually)
- Hire placement (300+ annually)
Network & Resources
Mayfield's 8,000 CXO Network spans:
- AI Sector: Anthropic, OpenAI, Google Cloud, AWS, NVIDIA, Cohere, Hugging Face, Mistral AI, Databricks
- Enterprise: Salesforce, ServiceNow, Snowflake, Microsoft, Oracle, SAP
- Infrastructure: GitHub, Stripe, HashiCorp partners
- Finance: Goldman Sachs, JPMorgan, Fidelity, BlackRock, Stripe, PayPal
- Healthcare: Kaiser Permanente, Cleveland Clinic, Mayo Clinic, major pharma
- Telecommunications: AT&T, Verizon, T-Mobile, international carriers
- Retail & Logistics: Walmart, Amazon, FedEx, Maersk
This network provides unparalleled customer development, beta testing, and go-to-market support.
Investment Confidence & Approach
Themes-Based Investing with Flexibility: Mayfield maintains prepared investment theses on:
- Cognition-as-a-Service (CaaS) and AI teammates
- Data economy and data infrastructure
- Developer-first era and DevOps
- Renaissance of semiconductors
- Cybersecurity at scale
- Deep tech and scientific computing
- Human health and longevity
But remains open-minded to breakthrough ideas outside these themes if thesis is compelling.
Due Diligence Intensity: Mayfield conducts thorough, multi-partner due diligence:
- Technical deep dives for infrastructure companies
- Market validation through network
- Founder reference checks
- Customer discovery calls
- Competitive landscape analysis
Corporate Structure & Fund Status
- Founded: 1969 (55+ years)
- Funds Raised: 20 U.S. funds to date
- Current AUM: $3 billion (Mayfield XVI and reserve capital)
- Current Fund Size: Mayfield XVI = $475M (inception stage focus)
- Fund Maturity: Mid-career fund, actively deploying
- Status: Actively accepting new investments, particularly in AI sector
- Office: Menlo Park, California (primary), with team presence in San Francisco
Conscious Capital & Values
Mayfield has integrated values-based investing:
- 1% Pledge: Commits 1% of management fees and carried interest annually to philanthropy (millions in impact)
- Diversity & Inclusion: Active program to increase diversity in portfolio and VC industry
- Access for All: Partnerships with community organizations to address systemic barriers
- AI Safety: Focus on ensuring AI is "a force for good"
Recent Thought Leadership
- 2026: Article "Why 2025 is the Start of a Golden Era for Startups" (noting $307B dry powder, AI-driven market)
- 2025: "The CaaS Revolution: Powering the Collaborative Intelligence Era"
- 2024: Mayfield AI Garage announcement (EIR-inspired AI teammate incubator with $100M allocation)
- Q1 2026: Active publishing on "Humans + AI" partnership philosophy
Investment Decision Factors
Highly Positive:
- Deep tech with defensible moat
- Experienced founding team from FAANG or successful startups
- Clear enterprise or infrastructure market
- AI as fundamental differentiation
- Warm introduction from trusted source
- Founder previously exited successfully
- Large TAM with network effects
Concerns/Flags:
- Crowded market without clear differentiation
- Solo founder (prefer co-founder teams)
- Unclear path to paying customers
- Early stage with no paying users yet (though acceptable for deep tech)
- Large expected sales cycle without distribution partners
- Weak investor references
- Overestimated market size or growth
Summary
Mayfield Fund represents a unique blend of 55+ year institutional expertise with contemporary focus on AI and collaborative intelligence. As a first-investor firm with $3B AUM and proven track record of 120+ IPOs and 225+ M&As, Mayfield offers not just capital but deep operational support, unparalleled network access, and founder-first partnership philosophy. For AI-first founders, particularly those building enterprise AI applications, AI teammates, or infrastructure, Mayfield is an ideal early-stage partner. Their measured approach (10 companies/year), collective intelligence decision-making, and hands-on board participation make them a valuable long-term partner from inception through growth stages.
Key Insight: Mayfield is best suited for founders building deep tech with defensible advantages, particularly in AI infrastructure or enterprise applications, who value partnership and operational support over rapid capital deployment.