19 VC firms investing in biotech & life sciences and logistics & supply chain at the Series A stage.
F4 Fund tracks 19 VC firms that actively invest in biotech & life sciences + logistics & supply chain at the Series A stage, with check sizes ranging from $25K – $5000M (median: $2.8M – $2.8M). As of June 2026, and 84% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,358+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ HCVC We back founders on a mission to industrialize scientific and technological progress. Hardtech startups solve difficult technological problems using interdisciplinary mixes of technology and engineering. We provide patient, supportive capital and community to help founders navigate R&D cycles and build technically defensible products. Paris | $100K – $2.5M | 30 | Leads | Active | ~2 mo | Open |
| 2 | ▶ Vertical Venture Partners Back founders with deep, first-hand domain expertise in specific industry verticals — those who have 'lived' the problem they are solving. Vertical-first software delivers faster time-to-value and stronger retention versus horizontal tools requiring heavy customization. Palo Alto | $500K – $4M | 47 | Both | Active | ~1 mo | Open |
| 3 | ▶ Susa Ventures Partner with spiky founders building category-defining companies using novel technological approaches. Focus on AI-driven innovation across alternative architectures, custom software, research assistants, TechBio, infrastructure, and enterprise applications. Provide capital, operational support, strategic guidance, and network access for founders with unique insights and deep technical expertise. San Francisco | $500K – $5M | 34 | Leads | Active | ~2 wks | Open |
| 4 | ▶ FTW Ventures The $12 trillion food and agriculture industries still rely on centuries-old methods. We back disruptive science and technology to modernize the food system—from biotech and sensors to automation and software—to feed 10 billion people by 2050 while preserving nature and nurturing humankind. San Francisco | $500K – $5M | 24 | Leads | Active | ~2 mo | Req'd |
| 5 | ▶ Story Ventures Story invests in the building blocks of automated systems across three interconnected layers: sensory systems (data capture), data processing (organization and structure), and machine intelligence (applications and decision-making). We believe the most impactful problems require the most innovative solutions, and we partner with founders pursuing audacious, challenging businesses because that's what it takes to create lasting impact. New York | $500K – $5M | 41 | Both | Active | ~1 mo | Req'd |
| 6 | ▶ 8VC Partner with elite founders building transformational technologies that create lasting economic and societal value. Focus on Smart Enterprise across five sectors: Logistics, Life Sciences, Healthcare, IT Infrastructure, and Government/Defense. Invest in platforms that enable human experts to solve non-linear problems through data integration and network effects. Austin | $500K – $50M | 30 | Leads | Active | ~2 wks | Open |
| 7 | ▶ Creative Ventures Humanizing deep tech by bringing advanced breakthrough technologies to where the people are and maximizing the value they generate for solving humanity's most critical crises. We invest in companies addressing climate, manufacturing labor shortages, healthcare costs, sustainable food production, and computing infrastructure. Oakland | $1M – $3M | 28 | Both | Active | ~1 mo | Req'd |
| 8 | ▶ Better Capital Day 0 venture capital applied by a deep operator. Better Capital invests at the earliest stage where ambiguity is highest and operator judgment adds the most value. Solo GP model keeps conviction high and enables deep engagement with 20-25 companies at critical inflection points. Pune | $300K – $1M | 47 | Leads | Active | ~1 wk | Req'd |
| 9 | ▶ Mubadala Mubadala partners with world-class companies and institutions to drive transformational growth across strategic sectors and geographies. We believe in long-term value creation through patient capital, operational expertise, and global partnerships aligned with Abu Dhabi's economic diversification. Abu Dhabi | $5M – $5000M | 41 | Both | Active | ~2 mo | Req'd |
| 10 | ▶ Sawari Ventures North Africa and Africa possess tremendous entrepreneurial talent. Strategic capital combined with operational expertise can unlock transformative solutions that reshape industries. We invest in founders solving region-critical problems. Cairo | $200K – $2M | 20 | Leads | Active | ~1 mo | Open |
| 11 | ▶ Snatched Ventures Backs DeepTech startups at the intersection of AI/ML, materials science, advanced manufacturing, biotechnology, optics, electronics, robotics, and blockchain — driving sustainable operational transformation across six thematics: transportation & logistics, energy & water, food & agriculture, fashion & beauty, precision medicine & aging, and retail & e-commerce. Requires commercial traction (min $1M revenue, 50%+ gross margins) and a minimum 10% ownership stake. San Francisco | $500K – $5M | 25 | Leads | Active | — | — |
| 12 | ▶ Greenoaks Greenoaks backs generation-defining technology companies with exceptional long-term growth potential. We make concentrated, large initial bets and maintain positions through multiple rounds and public markets, believing that exceptional founders and products deserve exceptional partnership. San Francisco | $25M – $75M | 20 | Both | Active | ~2 mo | Req'd |
| 13 | ▶ Expa We build category-defining companies through a combination of design, product, operations, and capital. We identify market gaps, pair brilliant founders with Expa's studio resources, and help them build companies that reshape entire industries. San Francisco | $500K – $5M | 60 | Leads | Active | ~1 wk | Open |
| 14 | ▶ Creative Destruction Lab The primary constraint for seed-stage, science-based entrepreneurs is access to experienced business judgment. CDL provides objective-based mentoring from accomplished entrepreneurs, angels, and scientists to help founders prioritize tasks and de-risk their businesses. Toronto | $50K – $250K | 20 | — | 1mo | ~2 wks | Open |
| 15 | ▶ Cathay Innovation Startups positioned as transformation partners with Fortune 500 corporates create the most impactful solutions. We believe the next generation of market leaders will emerge through collaborative innovation between startups and incumbent enterprises, supported by global expertise and capital. Paris | $5M – $100M | 16 | Both | Active | ~1 mo | Req'd |
| 16 | ▶ Gigafund Back the world's most ambitious and transformative entrepreneurs capable of building world-defining companies over 20+ years. Invest in founders with independent thought and first-principles vision to solve humanity's biggest problems across all sectors and geographies. Austin | $1M – $500M | 18 | Leads | Active | 3+ mo | Open |
| 17 | ▶ Flucas Ventures Democratize access to venture capital by building large syndicates of non-traditional LPs. Invest across all stages, sectors, and geographies based on founder quality and market conviction, not category restrictions. Enable 2,000+ diverse co-investors to participate alongside marquee firms like Sequoia and Andreessen Horowitz while maintaining founder-friendly economics. Miami | $250K – $5M | 17 | Follows | Active | ~1 wk | Req'd |
| 18 | ▶ Sher Ventures Exceptional founders applying unique talents and backgrounds to produce disruptive and differentiated products and services. Minimum $500K ARR at entry. Generalist across AI, B2B SaaS, logistics, healthcare, and advanced manufacturing. Sugar Land, TX | $25K – $100K | 4 | Follows | Active | ~1 mo | Open |
| 19 | ▶ IGC - Innovative Growth Capital IGC pioneered the Reverse VC™ model — starting with corporate demand rather than capital deployment. Their ReverseVision platform identifies what Global 5000 companies want to buy, then matches emerging tech founders to those demand signals. Investment flow: Demand → Commercialization → Valuation → Capital → Exit. This approach claims higher success rates, better deal terms, and reduced downside risk by replacing intuition with engineered outcomes. San Francisco | $25K – $500K | 1 | Leads | Active | ~1 mo | Open |
Investors on this page also frequently invest in these sectors
What other stages do these firms also invest in?
What other sectors do these firms also invest in?
F4 Fund tracks 19 VC firms that actively invest in biotech & life sciences + logistics & supply chain at the Series A stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for series a biotech & life sciences + logistics & supply chain investors is $2.8M – $2.8M, with a full range from $25K – $5000M. The distribution breaks down as: 3 firms in the <$500K range, 1 firms in the $500K-$1M range, 2 firms in the $1M-$2M range, 8 firms in the $2M-$5M range, 5 firms in the $10M+ range.
Among the 19 firms tracked, 84% lead or co-lead rounds, and 11% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best series a biotech & life sciences + logistics & supply chain investors combine domain expertise with an active portfolio in the space. Among these firms, 44% prefer warm introductions, and the average firm has 28 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.