20 VC firms investing in food & beverage and biotech & life sciences at the Series B stage.
F4 Fund tracks 20 VC firms that actively invest in food & beverage + biotech & life sciences at the Series B stage, with check sizes ranging from $1K – $340M (median: $5.3M – $5.3M). As of August 2026, and 80% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,831+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Digitalis Ventures Complex health problems require multidisciplinary teams combining deep technical, financial, and domain expertise. We invest in breakthrough science and technology-enabled solutions across human and animal health. New York | $250K – $50M | 54 | Leads | Active | ~2 mo | Req'd |
| 2 | ▶ Cultivian Sandbox Ventures Building next-generation food and agriculture technology companies that commercialize solutions for sustainable production, equitable distribution, and healthy consumption. Partners with strategic investors to drive systemic impact in food systems. Chicago | $1M – $10M | 22 | Both | Active | ~2 mo | Open |
| 3 | ▶ OYSTER BAY Venture Capital The way we nourish ourselves defines our future. We invest in rare founders disrupting the food system for better economic and ecological outcomes across the entire food value chain—from agriculture and inputs through food production, ingredients, consumer brands, and food service. We seek to partner with ambitious, resourceful founders who combine strong execution capability with deep commitment to positive impact. | $1M – $5M | 19 | Leads | Active | ~2 wks | Open |
| 4 | ▶ Acre Venture Partners Driving positive, lasting change in food and agriculture creates exceptional financial outcomes. Impact and return aren't trade-offs—they're intertwined. Both are essential. We invest in technologies and companies addressing human health, planetary well-being, responsible production, and climate solutions. Santa Monica | $500K – $5M | 29 | Leads | Active | ~1 mo | Req'd |
| 5 | ▶ DBL Partners Top-tier venture capital returns alongside meaningful social, environmental, and economic impact — the Double Bottom Line — with no tradeoff. DBL invests in mission-driven founders across clean energy, agriculture, nature-based solutions, health, economic opportunity, mobility, and the space/Earth nexus. San Francisco | $2M – $50M | 46 | Leads | Active | ~2 mo | N/A |
| 6 | ▶ AgFunder Progress in food, agriculture, and human health lags other sectors due to structural constraints. We invest in deep technologies that remove these bottlenecks at scale—whether AI, biology, robotics, or materials science. We're not intimidated by threats to the status quo. Silicon Valley | $500K – $5M | 41 | Both | Active | ~1 mo | Open |
| 7 | ▶ GrainInnovate Back startups - Australian or global - building software, hardware, biological, genetic, or business-model innovations that improve the future profitability and sustainability of Australia's grain growers. Sydney | $25K – $5M | 16 | Follows | Active | N/A | Open |
| 8 | ▶ LvlUp Ventures LvlUp backs founders across every stage, geography, and industry, using a large distributed network of associates and scouts to source and support a very high volume of small checks, paired with accelerator and mentorship infrastructure. New York | $1K – $1M | 37 | N/A | Active | N/A | Open |
| 9 | ▶ Collab Fund Investing at the intersection of for-profit and for-good. Companies that make the world better AND deliver strong financial returns. The Villain Test ensures both impact and profit alignment. New York | $500K – $10M | 45 | Leads | Active | ~2 wks | Open |
| 10 | ▶ Seventure Partners Seventure Partners identifies and backs innovative European companies in Life Sciences and Digital Technologies at all stages from seed to pre-IPO, serving as the lead investor and active board-level partner. The firm is a global pioneer in microbiome investing and has built a 25+ year track record of 150+ exits and 30 IPOs. Institutional backing from Natixis Investment Managers/Groupe BPCE provides unique co-investment and network access. Paris | $500K – $10M | 41 | Leads | Active | ~2 mo | Open |
| 11 | ▶ Lewis & Clark AgriFood Growth capital for the next AgriFood system — backing founders reshaping how the world eats, lives, and sustains itself, with active board involvement and operator-level support. St. Louis | $2M – $10M | 19 | Both | Active | N/A | N/A |
| 12 | ▶ Prelude Ventures Climate is the biggest challenge of our lifetime and the greatest business opportunity of the coming decades. We back visionaries accelerating climate innovation that will reshape our global economy for the betterment of people and planet. The most successful companies are born from a vision for a better future and the ability of that vision to create large, lasting positive impact. We invest in frontier technologies addressing climate across seven sectors: Built Environment, Carbon Management, Compute, Energy, Food & Agriculture, Manufacturing & Industrials, and Mobility. The best ideas come from everywhere—we operate where many venture firms can't or won't. San Francisco | $100K – $5M | 52 | Both | Active | ~2 mo | Open |
| 13 | ▶ Lerer Hippeau As founder-operators, we see returns in relationships. We back ambitious founders with exceptional vision at the earliest stages with capital, mentorship, and network access. | $100K – $1M | 73 | Leads | Active | ~1 mo | Open |
| 14 | ▶ Faering Capital Disciplined, sector-focused investing that develops proprietary investment themes ahead of the market, then partners with exceptional Indian entrepreneurs to help them navigate sustainable, category-leading growth. Mumbai | $10M – $50M | 32 | Leads | Active | N/A | Req'd |
| 15 | ▶ Snatched Ventures Backs DeepTech startups at the intersection of AI/ML, materials science, advanced manufacturing, biotechnology, optics, electronics, robotics, and blockchain — driving sustainable operational transformation across six thematics: transportation & logistics, energy & water, food & agriculture, fashion & beauty, precision medicine & aging, and retail & e-commerce. Requires commercial traction (min $1M revenue, 50%+ gross margins) and a minimum 10% ownership stake. San Francisco | $500K – $5M | 25 | Leads | Active | N/A | N/A |
| 16 | ▶ Odyssee Venture A growth accelerator for ambitious French companies built on a frank, direct and rapid entrepreneur-investor relationship, backing founders through start-up to pre-IPO growth phases with resilience and collective intelligence. Paris | $1M – $10M | 36 | N/A | Active | N/A | N/A |
| 17 | ▶ Redalpine Redalpine backs companies at the convergence of software and science — where rigorous engineering meets scientific breakthroughs. Half the team are scientists, half are operators, enabling them to engage deeply with highly technical founders and support them hands-on from day one through to exit. Primary focus areas: frontier science and biotech, digital health, AI and automation, fintech, synthetic biology, and climate tech. Zug | $500K – $5M | 40 | Leads | Active | N/A | N/A |
| 18 | ▶ Global Brain Broad-spectrum deep-tech and technology investor with particular conviction in AI, climate tech, and healthcare, pairing capital with hands-on operational support and open-innovation partnerships between startups and major Japanese corporations. Tokyo | $2M – $340M | 40 | Both | Active | ~1 mo | N/A |
| 19 | ▶ Trust Ventures Backs founders building generational companies in markets where public policy and regulation, not technology, are the primary barrier to progress -- energy, housing, healthcare, insurance, and advanced manufacturing. Pairs capital with in-house legal and policy strategy to help portfolio companies navigate and reshape regulatory environments. Austin | $250K – $30M | 19 | Follows | Active | N/A | N/A |
| 20 | ▶ Kaszek Partner with extraordinary founders building the next generation of iconic Latin American technology companies. Invest in any tech-enabled sector where innovation can drive significant disruption. Bring not just capital but deep operational expertise as former MercadoLibre executives and entrepreneurs. Buenos Aires | $500K – $50M | 61 | Leads | Active | ~1 mo | Open |
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What other sectors do these firms also invest in?
F4 Fund tracks 20 VC firms that actively invest in food & beverage + biotech & life sciences at the Series B stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for series b food & beverage + biotech & life sciences investors is $5.3M – $5.3M, with a full range from $1K – $340M. The distribution breaks down as: 2 firms in the $500K-$1M range, 7 firms in the $2M-$5M range, 5 firms in the $5M-$10M range, 6 firms in the $10M+ range.
Among the 20 firms tracked, 80% lead or co-lead rounds, and 10% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best series b food & beverage + biotech & life sciences investors combine domain expertise with an active portfolio in the space. Among these firms, 23% prefer warm introductions, and the average firm has 37 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.