8 VC firms investing in food & beverage and biotech & life sciences at the Series B stage.
F4 Fund tracks 8 VC firms that actively invest in food & beverage + biotech & life sciences at the Series B stage, with check sizes ranging from $100K – $50M (median: $5.3M – $5.3M). As of June 2026, and 100% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,356+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Digitalis Ventures Complex health problems require multidisciplinary teams combining deep technical, financial, and domain expertise. We invest in breakthrough science and technology-enabled solutions across human and animal health. New York | $250K – $50M | 54 | Leads | Active | ~2 mo | Req'd |
| 2 | ▶ Cultivian Sandbox Ventures Building next-generation food and agriculture technology companies that commercialize solutions for sustainable production, equitable distribution, and healthy consumption. Partners with strategic investors to drive systemic impact in food systems. Chicago | $1M – $10M | 21 | Both | Active | ~2 mo | Open |
| 3 | ▶ Acre Venture Partners Driving positive, lasting change in food and agriculture creates exceptional financial outcomes. Impact and return aren't trade-offs—they're intertwined. Both are essential. We invest in technologies and companies addressing human health, planetary well-being, responsible production, and climate solutions. Santa Monica | $500K – $5M | 29 | Leads | Active | ~1 mo | Req'd |
| 4 | ▶ DBL Partners Top-tier venture capital returns alongside meaningful social, environmental, and economic impact — the Double Bottom Line — with no tradeoff. DBL invests in mission-driven founders across clean energy, agriculture, nature-based solutions, health, economic opportunity, mobility, and the space/Earth nexus. San Francisco | $2M – $50M | 46 | Leads | Active | ~2 mo | — |
| 5 | ▶ AgFunder Progress in food, agriculture, and human health lags other sectors due to structural constraints. We invest in deep technologies that remove these bottlenecks at scale—whether AI, biology, robotics, or materials science. We're not intimidated by threats to the status quo. Silicon Valley | $500K – $5M | 34 | Both | Active | ~1 mo | Open |
| 6 | ▶ Collab Fund Investing at the intersection of for-profit and for-good. Companies that make the world better AND deliver strong financial returns. The Villain Test ensures both impact and profit alignment. New York | $500K – $10M | 44 | Leads | Active | ~2 wks | Open |
| 7 | ▶ Prelude Ventures Climate is the biggest challenge of our lifetime and the greatest business opportunity of the coming decades. We back visionaries accelerating climate innovation that will reshape our global economy for the betterment of people and planet. The most successful companies are born from a vision for a better future and the ability of that vision to create large, lasting positive impact. We invest in frontier technologies addressing climate across seven sectors: Built Environment, Carbon Management, Compute, Energy, Food & Agriculture, Manufacturing & Industrials, and Mobility. The best ideas come from everywhere—we operate where many venture firms can't or won't. San Francisco | $100K – $5M | 51 | Both | Active | ~2 mo | Open |
| 8 | ▶ Snatched Ventures Backs DeepTech startups at the intersection of AI/ML, materials science, advanced manufacturing, biotechnology, optics, electronics, robotics, and blockchain — driving sustainable operational transformation across six thematics: transportation & logistics, energy & water, food & agriculture, fashion & beauty, precision medicine & aging, and retail & e-commerce. Requires commercial traction (min $1M revenue, 50%+ gross margins) and a minimum 10% ownership stake. San Francisco | $500K – $5M | 25 | Leads | Active | — | — |
What other stages do these firms also invest in?
Investors on this page also frequently invest in these sectors
What other sectors do these firms also invest in?
F4 Fund tracks 8 VC firms that actively invest in food & beverage + biotech & life sciences at the Series B stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for series b food & beverage + biotech & life sciences investors is $5.3M – $5.3M, with a full range from $100K – $50M. The distribution breaks down as: 4 firms in the $2M-$5M range, 2 firms in the $5M-$10M range, 2 firms in the $10M+ range.
Among the 8 firms tracked, 100% lead or co-lead rounds. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best series b food & beverage + biotech & life sciences investors combine domain expertise with an active portfolio in the space. Among these firms, 33% prefer warm introductions, and the average firm has 38 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.