22 VC firms investing in insurance and healthcare & digital health at the Series B stage.
F4 Fund tracks 22 VC firms that actively invest in insurance + healthcare & digital health at the Series B stage, with check sizes ranging from $250K – $500M (median: $26M – $26M). As of August 2026, and 86% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,699+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Council Capital Achieve strong investment returns by investing in EBITDA-positive, founder-led healthcare companies that improve healthcare delivery. Apply the CEO Council Model — 34 senior healthcare operators who have personally invested $140M+ — to unlock growth through relationships, strategic insights, and hands-on value creation. Nashville | $10M – $50M | 25 | Leads | Active | ~2 mo | Open |
| 2 | ▶ Oak HC/FT Oak HC/FT partners with founders driving structural change in healthcare and financial services. They believe the most durable companies in the AI era will combine AI velocity with genuine understanding of how these industries work — including their regulatory, distribution, and trust dynamics. Interested in horizontal platforms that can penetrate and win in these complex, regulated sectors. Stamford | $1M – $100M | 34 | Leads | Active | ~1 mo | Open |
| 3 | ▶ Spark Capital Spark Capital backs transformative products built by creators with genuine vision and technical depth. We believe that the best way to evaluate a founding team is not through credentials or market analysis, but by experiencing their product firsthand. Product comes first, and everything else follows. | $500K – $60M | 65 | Both | Active | ~2 wks | Open |
| 4 | ▶ Sony Innovation Fund Actively champion founders and entrepreneurs, fostering a culture where startups thrive, while serving as the bridge to Sony that drives deeper engagements through technical expertise and network access. Focused on DeepTech, Entertainment, EnterpriseTech, Fintech/DLT, ClimateTech, and Location-Based Entertainment. Tokyo | $500K – $20M | 147 | Follows | Active | N/A | Open |
| 5 | ▶ Emergence Capital Emergence invests in early-stage B2B software companies that will define the next era of enterprise technology. Founded in 2003 as the original cloud/SaaS-focused VC firm, they have pioneered investing through technology transitions: horizontal SaaS (Salesforce, Zoom), vertical SaaS (Veeva, Doximity), and now AI-native services — companies that sell outcomes rather than software, powered by AI that compounds competitive advantage over time. San Francisco | $5M – $50M | 57 | Leads | Active | ~1 mo | Open |
| 6 | ▶ Mundi Ventures Mundi backs bold, purpose-driven founders building technology companies at the intersection of deep tech and critical global challenges. Core thesis: Europe has world-class talent and ecosystem but suffers from a scale-up funding gap at growth stages. Kembara fund (€750M) bridges this by providing Series B/C growth capital to European deep tech and climate champions. Madrid | $1M – $40M | 54 | Leads | Active | ~2 mo | Open |
| 7 | ▶ Madrona Venture Group Madrona invests in people and ideas for the long run — backing visionary founders building transformational technology companies, with deep focus on applied AI across domain-specific applications, AI infrastructure, developer tools, enterprise software, and AI-enabled biotech. The firm serves as an active, full-stack partner providing capital plus recruiting, business development, and customer introductions. Seattle | $500K – $50M | 52 | Leads | Active | ~1 mo | Open |
| 8 | ▶ Faering Capital Disciplined, sector-focused investing that develops proprietary investment themes ahead of the market, then partners with exceptional Indian entrepreneurs to help them navigate sustainable, category-leading growth. Mumbai | $10M – $50M | 32 | Leads | Active | N/A | Req'd |
| 9 | ▶ Impact America Fund Tech-enabled businesses built for and by people in marginalized communities create new frameworks of ownership and opportunity. Traditional VCs miss billion-dollar markets in overlooked communities. Oakland | $250K – $3M | 32 | Leads | Active | ~1 mo | Req'd |
| 10 | ▶ Thrive Capital Back great founders building category-defining companies, regardless of stage. We provide patient capital, hands-on operational support, and deep network access to enable breakout success. New York | $500K – $50M | 24 | Both | Active | ~2 wks | Req'd |
| 11 | ▶ White Star Capital Technology companies are becoming intertwined with the global economy more so than ever before. The most compelling founders build businesses through a broader world view. White Star Capital backs globally ambitious entrepreneurs at Series A, B, and Seed stages across North America, Europe, and Asia, helping them scale internationally through deep local presence on three continents. London | $1M – $25M | 45 | Leads | Active | ~1 mo | Open |
| 12 | ▶ RTP Global RTP Global is a self-funded, early-stage venture firm that recycles proceeds from prior wins (Datadog, Delivery Hero, Yandex, EPAM) to back technical, ambitious founders in AI, fintech, SaaS, developer tools, cybersecurity, e-commerce, and healthtech, with unusually flexible, long-duration capital and hands-on operator support. New York | $1M – $15M | 24 | Leads | Active | N/A | N/A |
| 13 | ▶ Trust Ventures Backs founders building generational companies in markets where public policy and regulation, not technology, are the primary barrier to progress -- energy, housing, healthcare, insurance, and advanced manufacturing. Pairs capital with in-house legal and policy strategy to help portfolio companies navigate and reshape regulatory environments. Austin | $250K – $30M | 19 | Follows | Active | N/A | N/A |
| 14 | ▶ Dragoneer Investment Group We target leading technology companies with sustainable differentiation and attractive unit economics, backing durable competitive moats such as network effects, proprietary data, and switching costs, and holding positions through full market cycles from late-stage private financing into public markets. San Francisco | $50M – $500M | 30 | Leads | Active | ~1 mo | Req'd |
| 15 | ▶ Kaszek Partner with extraordinary founders building the next generation of iconic Latin American technology companies. Invest in any tech-enabled sector where innovation can drive significant disruption. Bring not just capital but deep operational expertise as former MercadoLibre executives and entrepreneurs. Buenos Aires | $500K – $50M | 61 | Leads | Active | ~1 mo | Open |
| 16 | ▶ Hearst Ventures Strategic investments at the intersection of media, information, and technology, prioritizing businesses that benefit from Hearst operating expertise, distribution, and permanent capital. New York | $2M – $50M | 16 | Follows | Active | N/A | N/A |
| 17 | ▶ Streamlined Ventures Visionary founders are the true catalysts of transformation and progress. We partner with exceptional founders at the seed stage to help them build extraordinary companies through intensive operational support, structured tools, and candid guidance. Palo Alto | $250K – $10M | 26 | Leads | Active | ~2 wks | Open |
| 18 | ▶ Gigafund Back the world's most ambitious and transformative entrepreneurs capable of building world-defining companies over 20+ years. Invest in founders with independent thought and first-principles vision to solve humanity's biggest problems across all sectors and geographies. Austin | $1M – $500M | 18 | Leads | Active | 3+ mo | Open |
| 19 | ▶ Cathay Innovation Startups positioned as transformation partners with Fortune 500 corporates create the most impactful solutions. We believe the next generation of market leaders will emerge through collaborative innovation between startups and incumbent enterprises, supported by global expertise and capital. Paris | $5M – $100M | 22 | Both | Active | ~1 mo | Req'd |
| 20 | ▶ Caffeinated Capital Support founders pursuing their life's work with an alternative to the hype cycle: the luxury of long-term thinking. We support founders building category-defining companies across all sectors that will last for lifetimes. San Francisco | $1M – $5M | 19 | Leads | Active | N/A | N/A |
| 21 | ▶ Coatue The best investment opportunities emerge at the intersection of innovation and scale. We invest across the full lifecycle from seed to public markets, focusing on technology companies that will transform sectors globally with particular conviction in AI-enabled platforms and infrastructure. New York | $1M – $100M | 31 | Both | Active | ~2 wks | Open |
| 22 | ▶ Creaegis Back founders who are transforming industries and building great institutions, pairing strategic institutional equity with operational capabilities to bridge global/sovereign capital with high-potential Indian digital, consumer, and enterprise ecosystems. Bengaluru, India | $25M – $55M | 10 | Leads | Active | N/A | Req'd |
Investors on this page also frequently invest in these sectors
What other stages do these firms also invest in?
What other sectors do these firms also invest in?
F4 Fund tracks 22 VC firms that actively invest in insurance + healthcare & digital health at the Series B stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for series b insurance + healthcare & digital health investors is $26M – $26M, with a full range from $250K – $500M. The distribution breaks down as: 1 firms in the $1M-$2M range, 1 firms in the $2M-$5M range, 2 firms in the $5M-$10M range, 18 firms in the $10M+ range.
Among the 22 firms tracked, 86% lead or co-lead rounds, and 14% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best series b insurance + healthcare & digital health investors combine domain expertise with an active portfolio in the space. Among these firms, 33% prefer warm introductions, and the average firm has 38 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.