F4 Champions · Season 1
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F4 Champions · Season 1
You're researching investors. We want to see what you're building.
Join the open accelerator where your standing changes with what you ship. Enrollment closes August 2.
12 VC firms investing in marketing & adtech and biotech & life sciences at the Pre-Seed stage.
F4 Fund tracks 12 VC firms that actively invest in marketing & adtech + biotech & life sciences at the Pre-Seed stage, with check sizes ranging from $100K – $15M (median: $1.8M – $1.8M). As of July 2026, and 100% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,539+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Flagship Pioneering Create first-in-category bioplatform companies through scientific innovation and systematic entrepreneurship. Combine institutional scale with pioneer creativity to build breakthrough life sciences companies. Cambridge | $500K – $15M | 22 | Leads | Active | ~1 mo | Req'd |
| 2 | ▶ How Women Invest Women founders represent an overlooked asset class that delivers superior returns. Women-founded companies earn 26% more for investors, yet receive only 2% of venture funding. We invest exclusively in women-founded companies, providing capital, network access, and operational support to drive transformative change. San Francisco | $250K – $5M | 31 | Leads | Active | ~1 mo | Req'd |
| 3 | ▶ 42CAP Backing seed-stage, tech- and data-driven B2B software companies across Europe with global ambition. Focus on Agility Drivers (verticalized, consumerized, XaaS solutions) and Seductive Solutions with genuine product-market fit. Invest in AI-first and AI-enabled businesses as well as frontier tech (BioIT, Space, DLT, Quantum Computing). Munich | $500K – $3M | 56 | Leads | Active | N/A | N/A |
| 4 | ▶ Story Ventures Story invests in the building blocks of automated systems across three interconnected layers: sensory systems (data capture), data processing (organization and structure), and machine intelligence (applications and decision-making). We believe the most impactful problems require the most innovative solutions, and we partner with founders pursuing audacious, challenging businesses because that's what it takes to create lasting impact. New York | $500K – $5M | 44 | Both | Active | ~1 mo | Req'd |
| 5 | ▶ SciFi VC Partner with exceptional founders solving hard technical problems in fintech, AI, and science that require intense curiosity, intellectual depth, and scientific innovation. Focus on defensibility through hard technical feats, network effects, and solutions in complex, highly regulated industries. San Francisco | $100K – $1M | 25 | Leads | Active | ~2 wks | Req'd |
| 6 | ▶ Icehouse Ventures Back exceptional Kiwi founders building globally transformative companies, from day one to IPO. New Zealand founders represent a significantly undervalued asset class, and Icehouse provides capital plus an ecosystem of 3,000+ investors and deep operational support. Auckland | $100K – $10M | 41 | Leads | Active | ~2 mo | Open |
| 7 | ▶ IA Ventures Data is the defensible moat in technology. We invest in companies that build proprietary data assets, analytics capabilities, or machine learning advantages to dominate their categories. Founded on 'information arbitrage' thesis - applying hedge fund quantitative discipline to early-stage venture. New York | $250K – $750K | 16 | Leads | Active | ~2 wks | Open |
| 8 | ▶ ZhenFund Believe in innovation, risk-taking, and young talent. Best entrepreneurs are rare and precious. Provide quick capital, friendly terms, genuine commitment. Help but don't complicate. Monthly founder support. Beijing | $250K – $3M | 25 | Leads | Active | ~2 wks | Open |
| 9 | ▶ Kima Ventures Back ambitious teams with strong learning and execution capacities across all sectors, stages, and geographies. Technology-enabled businesses preferred. Volume-based, founder-centric investment philosophy. Paris | $100K – $200K | 25 | Leads | Active | ~2 wks | Open |
| 10 | ▶ Stout Street Capital Great startups can be built anywhere. We believe in founder-centric investing with operational support from a team of successful founders. We serve undernetworked geographic regions. Denver | $100K – $500K | 26 | Both | Active | ~2 wks | Open |
| 11 | ▶ Praetura Ventures Praetura backs ambitious northern founders building software, health, life sciences, fintech, cybersecurity, robotics, and other high-growth businesses where operator support and regional conviction matter. The firm positions itself as a more-than-money investor and emphasizes practical support from experienced operators, not just capital. Manchester, United Kingdom | $200K – $8M | 16 | Both | Active | N/A | Open |
| 12 | ▶ TheoryForge Operator-led fund investing in ambitious founders building transformative AI applications. We partner with technical founders who understand AI/ML deeply and are solving real customer problems with capital efficiency. Great product is always the best marketing. | $200K – $500K | 38 | Both | Active | ~2 wks | Req'd |
Investors on this page also frequently invest in these sectors
What other stages do these firms also invest in?
What other sectors do these firms also invest in?
Firms that frequently co-invest with investors on this page
F4 Fund tracks 12 VC firms that actively invest in marketing & adtech + biotech & life sciences at the Pre-Seed stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for pre-seed marketing & adtech + biotech & life sciences investors is $1.8M – $1.8M, with a full range from $100K – $15M. The distribution breaks down as: 3 firms in the <$500K range, 2 firms in the $500K-$1M range, 2 firms in the $1M-$2M range, 3 firms in the $2M-$5M range, 2 firms in the $5M-$10M range.
Among the 12 firms tracked, 100% lead or co-lead rounds. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best pre-seed marketing & adtech + biotech & life sciences investors combine domain expertise with an active portfolio in the space. Among these firms, 45% prefer warm introductions, and the average firm has 30 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.