Lodgepole Discovery is a Colorado-based protein engineering and discovery company combining computational design with experimental execution
Lodgepole Discovery is a Colorado-based protein engineering and discovery company combining computational design with experimental execution. We help biotechnology and pharmaceutical teams move from sequence to validated molecule through antibody and protein design, expression, purification, characterization, assay development, and iterative optimization. Our capabilities span antibodies, VHHs/nanobodies, peptides, enzymes, and other engineered proteins, with a focus on practical, decision-ready data and fast design–build–test cycles. Lodgepole operates at the intersection of computational protein engineering, automation, and laboratory science; giving clients a single partner for both in silico discovery and hands-on experimental work. Design it. Express it. Purify it. Characterize it. Iterate faster.