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Chamaeleon

chamaeleon.vc · San Francisco, CA

Investment thesis

Early-stage, product-led companies with differentiated technology and clear end-user flows, sourced globally and evaluated with a proprietary AI and quantitative engine (MANTIS).

$1M – $5M
Check Size
Leads & Follows
Lead Tendency
01Investment Thesis

Early-stage, product-led companies with differentiated technology and clear end-user flows, sourced globally and evaluated with a proprietary AI and quantitative engine (MANTIS).

02Investment Team
NG
Nuno Goncalves Pedro
Managing Partner
AS
Alex Santos
General Partner
AC
Armindo Costa
General Partner
03F4 Research Brief

Chamaeleon Research

Investment Thesis

Chamaeleon is an early-stage venture capital firm headquartered in San Francisco and Silicon Valley, with offices in Europe. It describes itself as three partners who have long collaborated as investors, operators and entrepreneurs, focused on truly transformative companies. The firm positions itself as data-driven and objective: its sourcing and diligence run on MANTIS, a proprietary AI and quantitative engine that the firm says analyzes millions of companies across thousands of data points per company. The pitch to founders is speed (quick decisions from more efficient, fact-based diligence), depth (understanding of markets and trends), no bias (global deal sourcing extended by analytic engines) and a humanist, all-hands-on-deck posture at key moments.

What They Look For

The manifesto states a broad vertical focus with a few principles. They prefer product-led companies, not just core technology or IP. They want clear end-user flows that the partners could test as users, even in B2B. They prefer technology that is differentiated. On founders, the approach page lists four traits: aware, flexible, balanced (value aligned, IQ plus EQ) and obsessed with execution and delivery.

Stage Focus

Typically coming in at Seed or Series A. The portfolio shows a mix of seed-stage bets and later participation in very large AI rounds.

Check Size

First checks between 1 and 5 million USD, per the manifesto.

Lead Tendency

They prefer to lead or co-lead, but state they play nicely with others. Recent public rounds show participation as a non-lead (for example the Snag seed, led by Slow Ventures), so the firm behaves as both.

Geographic Focus

Primarily the US and Europe, but will invest globally. Portfolio companies span the US, the UK, Portugal, Australia, Europe and Asia.

Recent Activity

The portfolio page lists latest announced investments including Jelled, Claid, Alpha, WorkWhile, Dirty Labs, DNK, Maximus, Mysten Labs, SensAI, Snag, Talofa Games, TourHero, Soter Analytics, Truleo, Coop, Vivum, Woolf University, Eridu AI, Bonfire Studios, Deepinfra, Spekter Games, You.com, Blaze, Runway, Kopra Bio and Humans&. Snag announced a $4M seed in September 2026 with Chamaeleon participating. Eridu emerged from stealth in March 2026 with a $200M Series A, and a Chamaeleon SPV was formed for Eridu. Public data sources do not show a fund size or AUM for the firm, so none is recorded here.

Portfolio Highlights

The firm's website marks these exits: Draft Kings (IPO, NASDAQ: DKNG), Robinhood (IPO, NASDAQ: HOOD), Rubrik (IPO, NYSE: RBRK), Enish (IPO, Tokyo: 3667), App Annie / Data.ai (sold to Sensor Tower), OhmConnect (merger with Google), Zya (sold to Google), Ziva (sold to Unity), Fyde (sold to Barracuda), Spin (sold to Ford), Style Sage (sold to Dassault Systemes), Bepro (merger with Taikai), Jelled (sold to Inflection AI), plus Outsystems and beamy (sold). Other prior investments include Gusto, Keepsafe, Irius Risk, Aptoide, Didimo, Jscrambler and Virta Health. Sectors span consumer apps, gaming, fintech, security, enterprise software, AI infrastructure and health.

Team

  • Nuno Goncalves Pedro, Managing Partner
  • Alex Santos, General Partner
  • Armindo Costa, General Partner

The leadership page cites 60+ investments led and executed, 40+ countries of network, 500+ people managed with budgets of $100M+ a year, and top 2 to 5 percentile returns as VC investors (firm claim).

Decision Process

A partnership of three, with a stated bias toward fast, fact-based decisions and an obligation to dissent, then dissent and commit. No formal committee is described.

Founder Preferences

Value alignment, low ego, intellectual honesty, high execution. They describe their network of founders and operators as KIN, a community that gets value-add support.

Gaps

No fund size, AUM or fund vintage on the site. Portfolio page gives no stage or date per company; only stage evidenced by a press source is recorded.

04Selected Portfolio
Biotech & Life Sciences
Blaze·Kopra Bio
Climate & Sustainability
OhmConnect
Consumer Apps & Social
SensAI·Keepsafe
Developer Tools & Infrastructure
Mysten Labs
E-commerce & Marketplaces
Aptoide·TheSkills·snag
EdTech
Woolf University
Enterprise Software
Jelled·Claid·Soter Analytics·Truleo·Eridu AI·DeepInfra·You.com·Runway·humans&·App Annie / Data.ai·Irius Risk·Ometria·Probably·Bepro·OutSystems·Sensei·Style Sage·Ziva·Fyde·Taskade
Fintech & Payments
Robinhood
Food & Beverage
Dirty Labs·Coop·Enish·Zya
Gaming
Talofa Games·Bonfire Studios·Didimo·Draft Kings
Healthcare & Digital Health
Maximus·Followapp·Virta Health
HR Tech & Future of Work
WorkWhile·Gusto
Insurance
Habit
Manufacturing & Industrial
Alpha
Marketing & Adtech
Advert.io·Mediaprobe·Beamy
Mobility & Transportation
Spin
Real Estate & PropTech
DNK
Robotics & Automation
Vivum
Security & Cybersecurity
Rubrik·Jscrambler
Travel & Hospitality
TourHero
Other
Spekter Games
Open the full portfolio→
05Recent Updates

Fresh signals from public announcements, essays, and portfolio activity.

Participated in Snag's $4M seed round led by Slow Ventures.
INVESTMENT·alleywatch.com+1
SEP 2026
06Frequent co-investors
IC
Iberis Capital
Both backed 4 of the same companies
Habit, Sensei, Mediaprobe, Jscrambler
3V
33N Ventures
Both backed 3 of the same companies
Fyde, OutSystems, Jscrambler
OC
Owl Capital
Both backed 3 of the same companies
Gusto, WorkWhile, OhmConnect
AV
Abstract Ventures
Both backed 2 of the same companies
Maximus, Blaze
AV
Alumni Ventures
Both backed 2 of the same companies
You.com, Mysten Labs
Find the investors for your round→
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AV
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Quick Reference
Check Size
$1M – $5M
Stages
Seed · Series A
Decision
Partnership
Location
San Francisco, CA
Sector Focus
Fintech & PaymentsConsumer Apps & SocialGamingEnterprise SoftwareDeveloper Tools & InfrastructureSecurity & Cybersecurity
Models
Product-Led Companies
Technology
AI/ML
See all Fintech & Payments investors →See all Consumer Apps & Social investors →See all Gaming investors →
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Focus Areas
Fintech & PaymentsConsumer Apps & SocialGamingEnterprise SoftwareDeveloper Tools & InfrastructureSecurity & Cybersecurity

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F4 Intelligence Report · Last Researched November 14, 2026F4 Research Engine