Myriad Venture Partners Research
Investment Thesis
Myriad Venture Partners is an early-stage venture capital firm founded in 2022 and based in Boston, Massachusetts. Launched publicly in January 2024 with $100 million in initial capital commitments (anchored by Xerox Corporation), the firm focuses on backing "exceptional founders building transformational B2B companies" across three core verticals: AI-first enterprise software, cybersecurity and developer infrastructure, and clean technology/industrial innovation.
The firm's differentiated approach—the "Myriad Model"—combines capital with a deeply curated ecosystem of corporate partners, Fortune 500 executives, and domain advisors who accelerate commercial traction for portfolio companies. Their Executive Advisory Board (30+ senior leaders from Mastercard, Oracle, Harley-Davidson, GSK, GitHub/Microsoft, and other Fortune 500s) acts as an operating extension of the firm, not a traditional advisory group. Since fund launch, they have facilitated 900+ enterprise introductions, 70 proof-of-concept engagements resulting in 24 commercial contracts, and portfolio company deployments across 119 Fortune 500 companies.
Stage Focus
Myriad invests primarily at the Pre-Seed and Seed stages, with selective participation at Series A when portfolio companies raise follow-on rounds. The firm is often the first institutional investor, establishing ownership positions early and providing strategic value before companies scale.
Check Size
The firm has not publicly disclosed specific check sizes. Based on observed round participation and fund size ($100M deployed across ~29 companies), estimated initial check sizes range from $250K to $3M, with possible lead positions up to $5M in larger Seed and Series A rounds.
Lead Tendency
Myriad consistently leads or co-leads investment rounds. Multiple portfolio company announcements credit them as a lead investor. For the Tessera Series A ($60M, May 2026), they co-invested alongside Andreessen Horowitz and Foundation Capital. For StrongSuit's Series A ($10M, July 2025), they co-led with Tandem Ventures and Foley & Lardner.
Recent Activity (2024-2026)
Myriad has been actively deploying from Myriad Venture Fund I ($100M initial commitments, launched January 2024):
- May 2026: Co-led Tessera's $60M Series A—an AI-native ERP migration platform deployed at Merck and Xerox
- January 2026: Invested in CVector—real-time operational economics engine for energy-intensive industries
- October 2025: Invested in Syntracts—legal knowledge management platform
- September 2025: Invested in Tato ($5M Seed)—enterprise digital transformation platform
- July 2025: Co-led StrongSuit Series A ($10M)—AI operating system for litigators (formerly CallidusAI)
- May 2025: Invested in Not Diamond—multi-model AI routing platform for enterprises
- April 2025: Invested in ClearCOGS—AI-powered predictive analytics for restaurant operations
- December 2024: Invested in Wexler AI ($5.3M Seed)—fact intelligence for legal professionals
- November 2024: Invested in Patlytics ($14M Series A)—patent intelligence platform
- October 2024: Invested in Cascade AI—AI assistants for HR and employee engagement
- August 2024: Invested in Climatize—funding gateway for clean energy projects
- June 2024: Invested in Pyte—secure computation platform (acquired February 2025)
- January 2024: Announced Myriad Venture Fund I ($100M)
Fund I portfolio has generated $433.8M in total capital raised, including $182.2M in 2024 alone. Three exits have been recorded: Vartana (acquired), Opus Security (acquired), Glean AI (acquired), and Pyte (acquired February 2025).
Portfolio Highlights
Notable portfolio companies include:
- Tessera – AI-native ERP migration platform (SAP, Oracle, Salesforce, Workday); $60M Series A; deployed at Merck and Xerox; co-investors include a16z and Foundation Capital
- Anvilogic – AI-powered security detection engineering; now at Series B
- LimaCharlie – SecOps cloud platform ("AWS of Cybersecurity"); provides endpoint security tools, telemetry storage, and incident response pipeline
- StrongSuit – AI operating system for litigators (formerly CallidusAI); $13M raised total
- Patlytics – Patent intelligence; $14M Series A
- Wexler AI – Fact intelligence for legal professionals; $5.3M Seed
- Seurat Technologies – Industrial decarbonization through distributed manufacturing (invested January 2022)
- Li Industries – Automated battery sorting and direct recycling of lithium-ion electrode materials
- Sentra – Cloud data security platform (acquired)
- Vartana – B2B enterprise sales closing and financing (acquired)
- LinkSquares – Legal contract management platform (milestone investment)
- Novity – Predictive maintenance with TruPrognostics AI for industrial assets
- BrontoSource – Software refactoring with compiler-level precision for legacy code modernization
- Fused – Serverless middleware platform for geospatial data and ML interoperability
Team
Chris Fisher, Managing Partner – Co-founder and Managing Partner. Previously founded Xerox Ventures ($250M fund) and served as SVP and Chief Strategy Officer at Xerox Holdings. Prior legal background at Ropes & Gray and Jenner & Block (early-stage investments, securities); banking background at Bank of America (structured finance). JD from DePaul University College of Law; BS in Business (Finance) from Ohio State Fisher College.
Tim Chiang, Partner – Deeptech, hardware, and cleantech specialist. MBA/MS from MIT Sloan School of Business and School of Engineering; BS in Materials Science from University of Illinois. Prior experience: GE Ventures (venture capital entry point), GC Ventures America (PTT Global Chemicals' CVC—advanced materials, additive manufacturing, energy storage), and Xerox. Focuses on cleantech, advanced manufacturing, robotics, material science, built environment, and mobility. Member of Chemical Angels Network and affiliated with Going VC Partners.
Dean Mai, Partner – Focuses on AI/compute, developer tools, cloud infrastructure, data platforms, security, and open-source. Prior: technology scouting at Dyson (AI/ML, energy storage, materials science), product/IP strategy at Bressler Group. Military: Deputy Commander of the 669th Special Rescue Tactical Unit, Israeli Air Force Special Operations. LLB from Reichman University (IP and Finance focus). Brings international network across US and Israel.
Sarah Adams, Partner & Head of Platform – Platform and ecosystem builder. Previously: founded Cribstone Ventures (angel fund for frontier technologies), Principal at Consello (M&A advisory for Fortune 500), Microsoft (launched first PE/VC strategy operating group), Goldman Sachs, JLL Partners, Duke Capital Partners. Early career: operator at enterprise SaaS startup in China. MBA from Duke University Fuqua School of Business; BA in History and Economics from Bowdoin College.
David Altman, Principal – Focuses on horizontal SaaS, vertical SaaS, marketplaces, and fintech. Prior: SVB Capital (early-stage and venture growth investments), Financial Technology Partners (investment banking in payments and embedded finance), Mastercard (product commercialization), Barclays (investment banking). BS from George Washington University (Economics and English). Active in GWU Economics Mentorship Program and the New York startup ecosystem.
Ryan Kilgallon, Senior Associate – Investment team member supporting deal sourcing and portfolio management.
Decision Process
Partnership-based decision process with multiple senior partners involved. Unusually, the firm's Executive Advisory Board (30+ Fortune 500 C-suite executives) plays a direct role in evaluating commercial viability and providing proof-of-concept access, giving Myriad a differentiated diligence advantage for B2B enterprise companies.
Geographic Focus
Primarily United States. The portfolio spans companies from across the US, with at least one Israeli-rooted investment (Sentra). Boston headquarters, though investments span the country including New York and Texas.
The Myriad Model—Differentiation
The firm's "Myriad Model" is its core differentiator: a three-pillar approach combining capital with strategic network access and operational expertise. Key metrics as of 2025-2026:
- 900+ startup-enterprise introductions facilitated
- 70 POC engagements, 24 resulting in commercial contracts
- 119 Fortune 500 companies using portfolio company technology
- 30+ Fortune 500 C-suite executives on Executive Advisory Board
This model positions Myriad as an accelerant for enterprise go-to-market, particularly for B2B software and AI companies that need Fortune 500 validation and first customers.
Anti-Thesis
Myriad avoids consumer applications, pure gaming, biotech/pharma, and pure hardware plays without a B2B software component. They focus exclusively on B2B contexts where their corporate network provides direct commercial value to portfolio companies.