7 VC firms investing in e-commerce & marketplaces and biotech & life sciences at the Growth stage.
F4 Fund tracks 7 VC firms that actively invest in e-commerce & marketplaces + biotech & life sciences at the Growth stage, with check sizes ranging from $200K – $2000M (median: $15.1M – $15.1M). As of August 2026, and 86% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,556+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Caffeinated Capital Support founders pursuing their life's work with an alternative to the hype cycle: the luxury of long-term thinking. We support founders building category-defining companies across all sectors that will last for lifetimes. San Francisco | $1M – $5M | 18 | Leads | Active | N/A | N/A |
| 2 | ▶ SpeedInvest Backs globally ambitious technology companies from pre-seed and seed through selected growth rounds using specialist EMEA sector teams and a platform model for capital, customers, talent, follow-on investors, and operational support. Vienna | $250K – $30M | 49 | Leads | Active | N/A | Open |
| 3 | ▶ Andreessen Horowitz Backing the builders of the next layer of computing across AI infrastructure, defense, biotech, and American dynamism. Former 'Software is Eating the World' thesis evolved to 'AI is Eating Software'. Partners with technical founders building foundation models, cloud systems, and infrastructure for the AI era. Menlo Park | $1M – $200M | 48 | Both | Active | ~2 wks | Open |
| 4 | ▶ Redalpine Redalpine backs companies at the convergence of software and science — where rigorous engineering meets scientific breakthroughs. Half the team are scientists, half are operators, enabling them to engage deeply with highly technical founders and support them hands-on from day one through to exit. Primary focus areas: frontier science and biotech, digital health, AI and automation, fintech, synthetic biology, and climate tech. Zug | $500K – $5M | 40 | Leads | Active | N/A | N/A |
| 5 | ▶ HongShan Back transformative entrepreneurs building category-defining companies across technology, healthcare, and consumer sectors, from seed to buyout. Partner with founders throughout the full company lifecycle with capital, operational support, and the network built over 20 years of China and global investing. Hong Kong | $500K – $2000M | 20 | Leads | Active | ~1 mo | Req'd |
| 6 | ▶ Gaingels Equity of access and representation in venture capital delivers positive returns. Diverse and underrepresented (including LGBTQ+) leaders of high-growth companies deserve capital access. When these founders succeed, they influence ecosystems and open doors for historically excluded groups. New York | $200K – $500K | 29 | Follows | Active | ~2 wks | Open |
| 7 | ▶ Cathay Innovation Startups positioned as transformation partners with Fortune 500 corporates create the most impactful solutions. We believe the next generation of market leaders will emerge through collaborative innovation between startups and incumbent enterprises, supported by global expertise and capital. Paris | $5M – $100M | 16 | Both | Active | ~1 mo | Req'd |
What other stages do these firms also invest in?
Investors on this page also frequently invest in these sectors
What other sectors do these firms also invest in?
F4 Fund tracks 7 VC firms that actively invest in e-commerce & marketplaces + biotech & life sciences at the Growth stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for growth e-commerce & marketplaces + biotech & life sciences investors is $15.1M – $15.1M, with a full range from $200K – $2000M. The distribution breaks down as: 1 firms in the <$500K range, 2 firms in the $2M-$5M range, 4 firms in the $10M+ range.
Among the 7 firms tracked, 86% lead or co-lead rounds, and 14% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best growth e-commerce & marketplaces + biotech & life sciences investors combine domain expertise with an active portfolio in the space. Among these firms, 40% prefer warm introductions, and the average firm has 31 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.