49 VC firms investing in healthcare & digital health at the Growth stage.
F4 Fund tracks 49 VC firms that actively invest in healthcare & digital health at the Growth stage, with check sizes ranging from $20K – $100000M (median: $25.1M – $25.1M). As of April 2026, and 94% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,092+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Frist Cressey Ventures Healthcare innovation that transforms care delivery, improves patient outcomes, and creates sustainable economic value for the healthcare system. FCV partners with founder-operators who combine clinical/healthcare expertise with operational excellence to build national-scale solutions addressing critical healthcare inefficiencies and access gaps. Nashville | $1M – $60M | 41 | Leads | Active | ~1 mo | Open |
| 2 | ▶ Initialized Capital Passion and vision matter more than pedigree. We seek founders with grit, audacity, and a spark of rebellion—regardless of background. We invest early, before success is inevitable, and support founders from 0-to-1 through Series A. San Francisco | $250K – $2M | 182 | Leads | Active | ~2 wks | Open |
| 3 | ▶ Point72 Ventures Point72 Ventures backs ambitious founders building for big outcomes across critical domains. Going deep, not wide—the firm focuses on specialized investment theses in AI, Consumer, and Defense Tech, bringing deep sector insights, partnership, and hands-on support from seed to pre-IPO. New York | $250K – $50M | 203 | Both | Active | ~2 wks | Req'd |
| 4 | ▶ Digitalis Ventures Complex health problems require multidisciplinary teams combining deep technical, financial, and domain expertise. We invest in breakthrough science and technology-enabled solutions across human and animal health. New York | $250K – $50M | 41 | Leads | Active | ~2 mo | Req'd |
| 5 | ▶ Red Swan Ventures Thematic-driven investor backing ambitious founders building for big outcomes across critical domains. Core conviction: defensible businesses create competitive advantages by transforming data challenges and market opportunities into sustainable value. We Go Deep, Not Wide. Focus on AI (defensible AI turns data challenges into advantages), Consumer (vision and strategy to break through attention economy), and Defense Tech (modern solutions for global stability). Active operational partnership beyond capital provision. | $250K – $100M | 65 | Leads | Active | ~2 wks | Open |
| 6 | ▶ Partners Resolute Invest in people and products that leverage technological breakthroughs or superior user experience to radically change the status quo. Focus on structurally sound, strategically defensible business models that create and capture new markets. True partnership approach: value-add extends beyond capital to include strategic guidance, operational expertise, and network introductions. | $250K – $8M | 54 | Leads | Active | ~2 wks | Open |
| 7 | ▶ Upfront Ventures Early investors and long-term partners. We back exceptional founders solving real problems across sectors. When you hit a bump in the road, we're there solving problems alongside you with operational expertise and network leverage. | $1M – $15M | 45 | Leads | Active | ~2 wks | Req'd |
| 8 | ▶ Makers Fund Backing builders of the future of interactive entertainment. We invest across games, content, platforms, and ecosystem technologies with conviction that visionary founders are driving transformation in how we play, watch, create, and live. | $500K – $5M | 152 | Leads | Active | ~2 wks | Open |
| 9 | ▶ Lightspeed Venture Partners We partner with bold builders of category-defining companies from Seed to Series F and beyond. Depth of commitment, depth of relationships, and depth of belief distinguish us. Complete immersion, authentic partnership, and unwavering conviction through market cycles. | $1M – $300M | 41 | Leads | Active | ~2 wks | Open |
| 10 | ▶ Radian Capital Radian Capital partners with software-driven B2B companies at scale, providing capital and hands-on operational support. They concentrate on select companies and go deep with each, emphasizing sustainable growth over growth at all costs. New York | $5M – $30M | 34 | Leads | Active | ~1 mo | Req'd |
| 11 | ▶ Northzone Category-defining entrepreneurs building fundamental shifts that upend entire industries. Focus on disruptive business models in energy transition, healthcare, AI, and consumer. Thesis values human relationships and founder-centric partnerships over financial metrics alone. London | $1M – $40M | 33 | Leads | Active | ~2 wks | Req'd |
| 12 | ▶ Giant Ventures The biggest companies of the century will be built solving the world's most pressing problems. We champion ambitious founders using technology to reshape civilization around climate, health, and inclusive capitalism. London | $500K – $15M | 30 | Both | Active | ~2 mo | Open |
| 13 | ▶ NVIDIA Expand the AI ecosystem by backing technology visionaries solving complex problems to reshape our world. Focus on game changers and market makers in AI, robotics, biotech, autonomous vehicles, and applied AI. Leverage NVIDIA's unique position as GPU infrastructure leader to identify and support companies that will drive adoption of NVIDIA technology. | $20M – $100000M | 30 | Both | Active | ~2 wks | Open |
| 14 | ▶ General Catalyst We back founders venturing beyond to build transformational companies that create positive, enduring change. Applied AI and global resilience are fundamental forces reshaping industries. | $2M – $50M | 29 | Leads | Active | — | — |
| 15 | ▶ Bond We identify and scale proven product-market-fit technology companies for global expansion and IPO readiness. Our partnership combines world-class macro research analysis with hands-on operational expertise from experienced technology leaders who have built and scaled billion-dollar companies. San Francisco | $1M – $50M | 40 | Leads | Active | ~2 mo | Open |
| 16 | ▶ IVP We supercharge growth in breakout companies, converting momentum into market dominance. We invest exclusively at Series B and beyond in companies that have achieved product-market fit and are ready to scale from millions to hundreds of millions in revenue. San Francisco | $1M – $25M | 25 | Leads | Active | ~2 mo | Req'd |
| 17 | ▶ AirTree Ventures Big things start small. We invest at seed stage and see potential where others don't. We believe in your vision for your company's future, not as it exists today. We think in decades, not days, committing to walk the entire journey with founders to build iconic companies. We share Antipodean ingenuity with the world. Sydney | $250K – $20M | 60 | Leads | Active | ~2 wks | Req'd |
| 18 | ▶ Thrive Capital Back great founders building category-defining companies, regardless of stage. We provide patient capital, hands-on operational support, and deep network access to enable breakout success. New York | $500K – $50M | 20 | Both | Active | ~2 wks | Req'd |
| 19 | ▶ B Capital Group Back extraordinary entrepreneurs throughout the company-building lifecycle from seed to IPO. Combine venture capital expertise with BCG management consulting to accelerate value creation. Support founders with capital, strategic guidance, and access to global networks. San Francisco | $250K – $50M | 30 | Leads | Active | ~2 wks | Req'd |
| 20 | ▶ Frontline Ventures The world's most successful B2B software companies require presence and success in both North America and Europe. Frontline specializes in facilitating frictionless transatlantic expansion, supporting founders with global ambition through a dual-fund strategy optimized for international growth. London | $250K – $20M | 19 | Both | Active | ~1 wk | Open |
| 21 | ▶ Coefficient Capital Consumer investing requires a fundamentally new playbook built for an omni-channel world where technology, data, and brand storytelling are deeply intertwined. Coefficient identifies growth-stage consumer businesses in established categories undergoing structural change, using proprietary data and an annual Consumer Trends Report to find category-defining brands early. Strategy centers on backing brands positioned for strategic exits to major CPG acquirers. New York | $2M – $40M | 17 | Leads | Active | ~1 mo | Open |
| 22 | ▶ Andreessen Horowitz Software is eating the world. Technology companies will transform every major industry. We invest in transformative technologies across AI, crypto, fintech, bio/health, enterprise, and consumer. We believe in backing exceptional founders and providing deep operational support to help them build enduring companies. Menlo Park | $1M – $200M | 44 | Both | Active | ~2 wks | Open |
| 23 | ▶ MassMutual Ventures Build category-defining technology businesses that deliver strong investment returns while addressing pressing business challenges. Leverage Fortune 500 parent (MassMutual) assets including real estate portfolios, renewable energy assets, and capital networks. Boston | $2M – $10M | 15 | Both | Active | ~1 mo | Open |
| 24 | ▶ Menlo Ventures Menlo invests in transformative technology companies at multiple stages of early growth. We provide capital, operational expertise, and hands-on support to help founders build scalable businesses that change how we live and work. San Francisco | $500K – $20M | 15 | Leads | Active | ~2 wks | Open |
| 25 | ▶ Redpoint Depth-first venture investing through mastery in specific domains. We partner with bold builders challenging industry conventions, backing founders with technical depth and conviction to build enduring $1B+ companies. Complete immersion creates enduring companies. Menlo Park | $500K – $50M | 15 | Leads | Active | ~2 wks | Open |
| 26 | ▶ Thesis Capital We invest in US-based, family-owned businesses in transition with $15-80M enterprise value and $3-25M in annual free cash flow. We bring patient capital, operational expertise, and long-term partnership mentality. Our favorite holding period is forever. We specialize in three partnership models: Legacy Transitions (60-100% acquisition for thoughtful handoffs), Growth Partnerships (51-80% acquisition for continued owner engagement), and Management Partnerships (support for operating leaders seeking autonomy). All partners have extensive operating experience as CEOs, Presidents, and Chairs. We invest with a 5-10+ year hold perspective, emphasizing stewardship, minimal leverage, and sustainable growth. | $5M – $80M | 8 | Leads | Active | ~2 mo | Req'd |
| 27 | ▶ Bain Capital Ventures Ambitious founders solving fundamental problems across major industries. The next generation of transformational companies will be built on modern AI, secure infrastructure, and efficient commerce. We partner with technical founders with operator experience and compelling narratives. San Francisco | $1M – $20M | 22 | Leads | Active | ~2 wks | Open |
| 28 | ▶ Kleiner Perkins Partner with exceptional founders building transformative technology companies from inception to IPO and beyond. Our moral compass is serving humanity with technology and capital. We provide not just capital but operational support, network access, and board participation to maximize the potential of founders' ideas and make history. Menlo Park | $100K – $150M | 20 | Leads | Active | ~2 wks | Open |
| 29 | ▶ Partech Partners We support ambitious founders solving large problems through technology across all stages. Independent thinkers who challenge conventional wisdom are our ideal partners. We provide not just capital but operational expertise, global networks, and hands-on support from day one through scale. Paris | $300K – $100M | 20 | Both | Active | ~1 mo | Open |
| 30 | ▶ Alumni Ventures We democratize venture capital by providing individual accredited investors with professional-grade access to elite venture opportunities. We leverage our massive 850,000+ community network and 11,000+ investors to create unique value for founders, sourcing and diligencing deals alongside top-tier VCs (a16z, Sequoia, Khosla) without leading rounds. Our network is our competitive advantage—it compounds value for all stakeholders. Manchester, NH | $250K – $5M | 54 | Follows | Active | ~2 wks | Open |
| 31 | ▶ Greycroft Partnering with brilliant founders to upend the status quo by investing in AI-driven software, sustainability technologies, and innovative consumer brands. We believe AI will dominate software over the next decade, and we seek to support founders reimagining industries across all three sectors. New York | $2M – $100M | 43 | Leads | Active | ~2 wks | Open |
| 32 | ▶ K5 Global K5 Global backs category-defining companies from inception to IPO. The firm leverages exceptional networks across media, entertainment, politics, finance, and technology to provide strategic value beyond capital. We believe the best companies are built by founders who can access world-class talent, capital, and strategic relationships. Los Angeles | $1M – $3M | 30 | Leads | Active | ~1 mo | Open |
| 33 | ▶ WndrCo WndrCo positions itself as 'the founders behind the founders,' combining strategic capital with deep operational involvement. Unlike traditional VCs, partners take formal operating roles (interim CEO, CFO, CPO) within portfolio companies. This approach leverages the co-founders' proven track record: Sujay Jaswa scaled Dropbox from $18M to $10B as Business Founder/CFO, and Jeffrey Katzenberg transformed Disney Studios and built DreamWorks. The firm invests across all stages through three strategies: Build (acquiring underappreciated tech companies), Venture (leading post-PMF rounds), and Seed (very early checks). Focus areas are Future of Work, Cybersecurity, Developer Infrastructure, and Consumer Technology, with increasing emphasis on AI applications. Beverly Hills, California | $100K – $10M | 30 | Leads | Active | ~2 wks | Req'd |
| 34 | ▶ Google Launchpad Accelerator Innovative technology entrepreneurs exist globally, particularly in emerging markets, and deserve access to world-class mentorship, infrastructure, and Google's vast product ecosystem. We support founders who have proven product-market fit in their home markets and are ready to expand internationally. Mountain View | $20K – $100K | 15 | — | Active | ~1 mo | Open |
| 35 | ▶ Plymouth Growth Exceptional founder-led B2B technology businesses exist outside traditional coastal venture and PE systems. We back gritty founders who think differently and approach sustainable, balanced growth without venture-style moonshot pressure or traditional PE playbooks. Detroit | $5M – $25M | 15 | Leads | Active | ~1 mo | Open |
| 36 | ▶ Rosecliff Ventures We seek to create positive economic impact and long-term value by providing lifetime support to companies from seed through late-stage equity and credit. We differentiate through deep Wall Street expertise, strategic LP networks, and innovative financing vehicles. New York | $500K – $10M | 20 | Both | Active | ~2 mo | Open |
| 37 | ▶ Valor Capital Group Greatest opportunities come from serving unmet needs of the middle class in emerging markets. We bridge US and Latin American markets, providing institutional capital, intellectual capital flow, and geo arbitrage exit opportunities. New York | $500K – $10M | 20 | Leads | Active | ~2 wks | Open |
| 38 | ▶ Mubadala Mubadala partners with world-class companies and institutions to drive transformational growth across strategic sectors and geographies. We believe in long-term value creation through patient capital, operational expertise, and global partnerships aligned with Abu Dhabi's economic diversification. Abu Dhabi | $5M – $5000M | 36 | Both | Active | ~2 mo | Req'd |
| 39 | ▶ Left Lane Capital Invest in hyper-growth consumer and technology businesses with enduring customer relationships. Back founders challenging the status quo through digital transformation. Focus on companies with strong unit economics, loyal customer bases, and defensible competitive advantages in complex, regulation-heavy markets. Brooklyn | $5M – $50M | 35 | Both | Active | ~2 wks | Open |
| 40 | ▶ Emerson Collective Emerson Collective invests in entrepreneurs and innovators driven by purpose, seeking consequential companies that deliver both generational impact and venture-scale returns. The firm targets sectors where biggest market opportunities meet meaningful impact levers: energy & environment, digital health, fintech, education, work, and media. Palo Alto | $10M – $700M | 12 | Both | Active | ~1 mo | Req'd |
| 41 | ▶ Foundry Group We invest in startups and venture funds, creating a symbiotic network that propels innovation. Our approach is characterized by long-term thinking and a 'give first' philosophy. Boulder, Colorado | $500K – $10M | 20 | Leads | Active | ~1 mo | Req'd |
| 42 | ▶ Goodwater Capital Consumer technology has the power to measurably improve billions of lives across the globe. We invest in exceptional entrepreneurs building digital utilities that provide better access to housing, healthcare, food, financial services, transportation, education, and entertainment globally. Burlingame, California | $5M – $50M | 25 | Leads | Active | ~1 mo | Req'd |
| 43 | ▶ Coatue The best investment opportunities emerge at the intersection of innovation and scale. We invest across the full lifecycle from seed to public markets, focusing on technology companies that will transform sectors globally with particular conviction in AI-enabled platforms and infrastructure. New York | $1M – $100M | 25 | Both | Active | ~2 wks | Open |
| 44 | ▶ Peak XV Partners Outlier founders and ideas shape the future of humanity. We back ambitious founders building category-defining companies that create significant impact while generating returns that support non-profit and educational causes. Bangalore | $500K – $100M | 15 | Leads | Active | ~2 wks | Open |
| 45 | ▶ Gaingels Equity of access and representation in venture capital delivers positive returns. Diverse and underrepresented (including LGBTQ+) leaders of high-growth companies deserve capital access. When these founders succeed, they influence ecosystems and open doors for historically excluded groups. New York | $200K – $500K | 20 | Follows | Active | ~2 wks | Open |
| 46 | ▶ Tiger Global Management Leading global companies that leverage technological innovation across public and private markets. Proven founders (especially ex-Googlers, AWS, Stripe) with large TAMs (billions+), product-led growth, and global ambitions. Conviction-based investing post-2022 correction emphasizing quality over quantity. New York | $1M – $100M | 20 | Leads | Active | ~1 wk | Req'd |
| 47 | ▶ Evolution Venture Capital Partners Culture-Tech companies that disrupt and define how we live, work, play, and interact with the world every day. We invest in passionate founders building transformative products that change cultural behaviors. New York | $500K – $6M | 20 | Leads | Active | ~1 wk | Open |
| 48 | ▶ Insight Partners Software founders need more than capital to scale successfully. Insight Partners combines investment capital with hands-on operational expertise, embedded teams, and network access to accelerate company growth across all stages. New York | $10M – $350M | 20 | Leads | Active | ~1 mo | Open |
| 49 | ▶ Cathay Innovation Startups positioned as transformation partners with Fortune 500 corporates create the most impactful solutions. We believe the next generation of market leaders will emerge through collaborative innovation between startups and incumbent enterprises, supported by global expertise and capital. Paris | $5M – $100M | 12 | Both | Active | ~1 mo | Req'd |
Investors on this page also frequently invest in these sectors
What other stages do these firms also invest in?
What other sectors do these firms also invest in?
Firms that frequently co-invest with investors on this page
F4 Fund tracks 49 VC firms that actively invest in healthcare & digital health at the Growth stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for growth healthcare & digital health investors is $25.1M – $25.1M, with a full range from $20K – $100000M. The distribution breaks down as: 2 firms in the <$500K range, 1 firms in the $1M-$2M range, 5 firms in the $2M-$5M range, 7 firms in the $5M-$10M range, 34 firms in the $10M+ range.
Among the 49 firms tracked, 94% lead or co-lead rounds, and 4% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best growth healthcare & digital health investors combine domain expertise with an active portfolio in the space. Among these firms, 35% prefer warm introductions, and the average firm has 37 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.