8 VC firms investing in enterprise software and agetech & longevity, ranked by portfolio depth and activity.
F4 Fund tracks 8 VC firms that actively invest in enterprise software + agetech & longevity, with check sizes ranging from $100K – $5M (median: $1.1M – $1.1M). As of August 2026, and 75% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,556+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Equitage Ventures Backs early-stage AgeTech, senior-care, digital-health, and technology-enabled services companies transforming the aging journey, using a senior-care operator and LP network to help with distribution, diligence, product feedback, talent, and go-to-market. Denver | $250K – $2.5M | 23 | N/A | Active | ~1 mo | Open |
| 2 | ▶ Supernode Global We invest in early-stage consumer and B2B technologies that meaningfully enhance personal and professional lives. We back application-layer software with consumer-grade UX that people actually use every day. Our focus: Wellbeing (health & vitality, life optimization, community & social) and Productivity (intelligent workflows, creative enablement, professional augmentation). | $500K – $3M | 27 | Leads | Active | ~1 wk | Req'd |
| 3 | ▶ Springbank Collective We invest in mission-critical infrastructure serving women and working families. Many essential systems have been dismissed as too complex or too human to solve, but technology and AI advances make transformation possible. This is a $1 trillion opportunity and generational economic growth driver. New York | $250K – $2M | 36 | Leads | Active | ~2 wks | Open |
| 4 | ▶ The Helm Women receive only 2% of venture capital despite female-founded startups delivering 2x return per dollar vs. all-male teams. The Helm invests in game-changing, undervalued companies at seed stage founded by women, providing not just capital but operational support and ecosystem access. New York | $250K – $1.5M | 27 | Leads | Active | ~2 wks | Open |
| 5 | ▶ Concrete Rose Capital We invest financial and social capital into exceptional ventures led by visionary, values-aligned teams. Technology is the 'new West' - we seek to broaden opportunities by partnering with pioneering founders to bring entire communities along on their journey of reimagining the world. San Francisco | $100K – $5M | 47 | Both | Active | ~2 mo | Open |
| 6 | ▶ LOI Venture Back the brightest early-stage founders under 30. We provide capital, mentorship, and network access to accelerate ambitious young entrepreneurs who graduate from our League of Innovators program or demonstrate exceptional founder quality. Vancouver | $100K – $1M | 35 | Leads | Active | ~2 wks | Open |
| 7 | ▶ Kaedan Capital Entrepreneur-centric private investment firm backing Israeli-related seed to early-stage ventures across diverse technology areas. Patient partners who allow founders to build global tech companies at their own pace. Tel Aviv | $250K – $1.5M | 21 | N/A | Active | ~1 mo | Open |
| 8 | ▶ TheoryForge Operator-led fund investing in ambitious founders building transformative AI applications. We partner with technical founders who understand AI/ML deeply and are solving real customer problems with capital efficiency. Great product is always the best marketing. | $200K – $500K | 38 | Both | Active | ~2 wks | Req'd |
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Firms that frequently co-invest with investors on this page
F4 Fund tracks 8 VC firms that actively invest in enterprise software + agetech & longevity. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for enterprise software + agetech & longevity investors is $1.1M – $1.1M, with a full range from $100K – $5M. The distribution breaks down as: 1 firms in the <$500K range, 3 firms in the $500K-$1M range, 3 firms in the $1M-$2M range, 1 firms in the $2M-$5M range.
Among the 8 firms tracked, 75% lead or co-lead rounds. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best enterprise software + agetech & longevity investors combine domain expertise with an active portfolio in the space. Among these firms, 25% prefer warm introductions, and the average firm has 32 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.