Best Series A HR Tech & Future of Work + Healthcare & Digital Health Investors 2026

We invest in companies intentionally closing gaps in wealth, health, and skills through our Inclusive Investing™ framework. Exceptional founders and transformative opportunities exist far beyond traditional VC hubs; we target overlooked founders building category-leading businesses with systemic impact.

We back exceptional founders who elevate human potential and ignite purpose across learning, health, and work. When people are equipped to grow their skills, nurture relationships, be healthy, and find meaning in what they do, communities thrive.

Ecosystem-driven VC backing B2B companies transforming health, wealth, and work. The SemperSystem network of 200+ Fortune 500 buyers (ADP, Paychex, Cigna, MetLife, Unum) provides portfolio companies with enterprise GTM acceleration in complex regulated markets.

Backing transformative founders building exceptional companies across all sectors

Built for entrepreneurs, by entrepreneurs — NCV invests thematically in Next Coast markets (Austin, Midwest, Mountain West) at the Seed/Series A inflection point. They back glass-eating founders building category-defining companies in large markets, providing capital plus hands-on company building support via their 150+ expert network.

Impact capital can address structural problems in America's $1 trillion education and workforce system. With 6 in 10 Americans holding less than bachelor's degrees and 40% of recent grads underemployed, we partner with founders removing barriers across the learner journey - from equitable access through career success.

Software++ — mission-critical enterprise technology companies with differentiated tech and multi-layered monetization strategies beyond standard SaaS licensing. Seeks proprietary data, network effects, and workflow lock-in.

Invest in technology businesses with venture-pace growth potential, high margins, recurring revenue, and sustainable competitive advantage. Back exceptional founders who harbor passion to build great companies and are magnets for talent. Commit time, energy, network and hard work to portfolio company success, not just capital.

Disruptive innovation in work and education fuels human achievement. We partner with exceptional entrepreneurs who are business builders, deep domain experts, and capital efficient thinkers. We believe in long-term relationships over transactional investing, often partnering with founders across multiple ventures.

The next decade will be defined by the addition of machine intelligence to software. Scale backs 'Cognitive Apps' — AI-powered applications that augment manual work and enable data-driven predictions — partnering with founders who can transition from founder-led to scalable go-to-market, accompanying them from Series A through IPO.

First institutional VC fund exclusively founded by former corporate VC leaders. Bridges traditional VC and corporate VC through Counter Club (750+ CVCs, $320B deployed). Invests in B2B SaaS solving nontrivial problems in large markets, providing founders with direct access to enterprise customers, strategic partners, and capital through the CVC network.

Technology that creates opportunity for the entire workforce through skills development, new work models, and portable benefits—excluding automation-first themes. We invest in companies that help humans adapt and thrive through economic transitions, with focus on rural and middle-skill America.

MS&AD Ventures partners with visionary entrepreneurs to create innovative solutions across insurance, financial services, healthcare, and sustainability. Backed by the 5th largest global insurance conglomerate, they bring capital plus global distribution across 47 countries. They move fast (2-week decisions), focus on partnerships over ownership, and help companies scale internationally.

EPIC Ventures backs early-stage technology companies building in the information economy, with a focus on enterprise SaaS, healthcare technology, cybersecurity, and future of work. The firm believes the best way to build lasting companies is through genuine partnership with founders — providing capital, strategic guidance, operational expertise, and deep network access. Founded in 1994, EPIC helped build the Utah tech ecosystem and continues to be the foundational VC of the Mountain West.

We invest in mission-critical infrastructure serving women and working families. Many essential systems have been dismissed as too complex or too human to solve, but technology and AI advances make transformation possible. This is a $1 trillion opportunity and generational economic growth driver.

Emergence invests in early-stage B2B software companies that will define the next era of enterprise technology. Founded in 2003 as the original cloud/SaaS-focused VC firm, they have pioneered investing through technology transitions: horizontal SaaS (Salesforce, Zoom), vertical SaaS (Veeva, Doximity), and now AI-native services — companies that sell outcomes rather than software, powered by AI that compounds competitive advantage over time.

Partner with extraordinary founders building the next generation of iconic Latin American technology companies. Invest in any tech-enabled sector where innovation can drive significant disruption. Bring not just capital but deep operational expertise as former MercadoLibre executives and entrepreneurs.

Back focused founders solving real problems in markets they understand deeply, with clarity, discipline, and drive. Seek companies with motivated teams, strong product vision, scalable business models, and large addressable markets.

Invest in visionary founders from Latinx and diverse backgrounds building disruptive tech solutions. Capitalize on demographic trends and founder quality in systematically underestimated segments. Create alpha through early-mover advantage in overlooked founder networks.

The best way to find and support AI companies is to be one ourselves. We back independent thinkers building real systems before consensus forms, partnering as radical learning partners from day one.

Kalos backs founders building at the intersection of AI/automation/robotics and rapid demographic change — specifically in workforce, care, and education. They seek founders with unique market experience and systems-level thinking who can drive structural change in undercapitalized but critical sectors.

We identify exceptional operators with proven track records at scale (ex-Facebook, Google, Stripe) and catalyze their transition into founders. Periods of rapid societal behavior change spur dramatic innovation. We invest in the future of work and consumer utility, providing not just capital but operational expertise, network access, and proven playbooks from building at Facebook/Meta scale.

First women-led VC investing in underrepresented founders solving underserved problems in undercapitalized geographies. We capitalize on three biggest arbitrage opportunities: diversity of founders, geographic expansion beyond Silicon Valley, and problems with meaningful social impact. We back exceptional teams in consumer tech, digital health, and future of work sectors.

Back electric founders with an uncontrollable passion for creating disruptive companies. Invest globally, particularly strong in US and Latin America. Combine capital with operational support through venture studio model, helping build groundbreaking companies from inception through scale.

Seeking early-stage alpha through institutional discipline. ATX VP invests in people pioneering the future by combining Wall Street rigor with deep operating experience. Core focus on disruptive B2B software, APIs, frontier tech, and marketplaces across Supply Chain, FinTech, InsurTech, HR Tech, Aerospace, and Future of Work.

Fund economic resilience of underserved entrepreneurial households through early-growth capital in businesses where impact and commercial performance are structurally aligned. Invest in companies democratizing access to essential products and services across financial inclusion, education, healthcare, agri-supply chains, and MSME solutions.

Founders closest to the problem—particularly those from historically overlooked communities—are best positioned to solve it. We invest at the intersection of innovation and inclusion in the building blocks of shared prosperity: economic mobility, healthcare access, and community infrastructure. Perspective and proximity are power.

Mercury backs disruptive AI and Blockchain-enabled startups outside Silicon Valley, with a focus on capital-efficient founders in the Central US reimagining core industries including fintech, enterprise software, healthcare, energy, manufacturing, and logistics through their five investment themes: Work, Build, Journeys, Data, and Power.

Venture capital can achieve both financial returns and positive social impact. Founders with lived experience in underrepresented communities identify rapidly-scalable solutions others overlook. Diversity and inclusive business practices drive superior returns and competitive advantage.

We back founders building commercially successful businesses that expand economic mobility in America. We invest where capitalism's incentives align with social benefit, embedding mobility impact in core product, not as an afterthought.

Close the funding gap for women-led ventures at early and growth stages. Investing in women is an economic opportunity, good for business, and the right thing to do. Build a portfolio of diverse founders and industries.

Invest in the future of software built on AI. We partner with technical founders to provide capital, unfair shortcuts, and operational support to accelerate their learning and help them reach their potential. We position ourselves as the first institutional investor for v0.9 stage founders.

Help founders build companies of which they can be proud. We invest in mission-driven founders solving large, urgent problems using technology to create substantive change. Capital is necessary but not sufficient—sweat, reputation, and accountability are our core commitments.

Partner with founders building generational software companies. We provide capital, operational support, and genuine partnership. Focus on technology-driven solutions addressing large and growing markets. Invest across enterprise and consumer software, with depth in AI-native software, fintech, infrastructure, security, vertical SaaS, healthcare, and future of work.

Back Latin American founders with global ambitions who use technology and AI to solve hard, inefficient markets in fintech, commerce, human capital, health, smart cities, and related large regional opportunities.

Exceptional founder-led B2B technology businesses exist outside traditional coastal venture and PE systems. We back gritty founders who think differently and approach sustainable, balanced growth without venture-style moonshot pressure or traditional PE playbooks.

The hardest thing in seed is finding product-market fit. We help you find it. If you already have product-market fit, we will help you scale. We partner with exceptionally ambitious founders for the long run and provide capital combined with operational expertise through our 100+ member Product Council.

Coach and invest in entrepreneurial leaders building world-class, purpose-driven organizations. Combines financial investment with active leadership coaching and organizational development using LinkedIn's proven playbook. Believes great companies are built by great leaders who manage compassionately and combine doing well with doing good.

We back the companies of tomorrow before it's obvious. We combine early-stage European investing with a permanent San Francisco presence to help founders build category-defining global companies. We invest in ambitious technical founders who deeply understand industry transformation.

We invest financial and social capital into exceptional ventures led by visionary, values-aligned teams. Technology is the 'new West' - we seek to broaden opportunities by partnering with pioneering founders to bring entire communities along on their journey of reimagining the world.

Cherryrock Capital backs underinvested entrepreneurs — specifically Black and Latine founders — building transformative software companies. They invest in the possible, seeking founders with domain expertise, compelling right-to-win stories, and products that generate measurable customer outcomes in structurally underserved markets.

The best investment opportunities emerge at the intersection of innovation and scale. We invest across the full lifecycle from seed to public markets, focusing on technology companies that will transform sectors globally with particular conviction in AI-enabled platforms and infrastructure.

Early-stage technology companies solving hard business problems with SaaS, cloud, mobile, and disruptive technologies. We back technical founders with domain expertise and market understanding across diverse sectors.

Early-stage venture capital for IT and Biotech companies in Colorado Front Range and Mid-Atlantic. Focus on experienced founding teams solving important problems with potential for significant financial returns. Patient capital approach with operational support and deep regional networks.

Latino founders represent an underserved but exceptionally talented segment of the entrepreneurial ecosystem. We invest in visionary founders who combine bold ideas with execution excellence to build scalable, high-impact businesses that create both economic and social value. We believe institutional capital paired with strategic partnership from Fortune 100 executives and operating experts can unlock the full potential of Latino-led innovation.

Underestimated founders are systematically mispriced assets that create alpha rather than requiring concessionary returns. We invest in the very best founders who identify as women, people of color, or LGBTQ, treating capital allocation as activism.

We build category-defining companies through a combination of design, product, operations, and capital. We identify market gaps, pair brilliant founders with Expa's studio resources, and help them build companies that reshape entire industries.

Consumer technology has the power to measurably improve billions of lives across the globe. We invest in exceptional entrepreneurs building digital utilities that provide better access to housing, healthcare, food, financial services, transportation, education, and entertainment globally.

Empowering entrepreneurs to reimagine the way we live and work by investing in daring technology companies challenging the status quo with permanent capital, lifelong sparring partnership from pre-seed through IPO and beyond.

Elevate Ventures partners with innovation-driven founders to provide strategic capital, mentorship, and ecosystem access. Founded by a former founder (Governor Mitch Daniels), the firm believes the best founders exhibit grit, creativity, and coachability. They invest across all sectors and geographies but maintain primary focus on Indiana and Great Lakes Region entrepreneurs building cross-sector innovations.

Software founders need more than capital to scale successfully. Insight Partners combines investment capital with hands-on operational expertise, embedded teams, and network access to accelerate company growth across all stages.

Great startups can be built anywhere. We believe in founder-centric investing with operational support from a team of successful founders. We serve undernetworked geographic regions.

Exceptional founders applying unique talents and backgrounds to produce disruptive and differentiated products and services. Minimum $500K ARR at entry. Generalist across AI, B2B SaaS, logistics, healthcare, and advanced manufacturing.