7 VC firms investing in travel & hospitality and biotech & life sciences, ranked by portfolio depth and activity.
F4 Fund tracks 7 VC firms that actively invest in travel & hospitality + biotech & life sciences, with check sizes ranging from $50K – $50M (median: $625K – $625K). As of August 2026, and 57% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,644+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Montage Ventures Montage Ventures aims to support radical thinkers who are bringing new ideas and platforms to foster change within the financial services, commerce and health sectors, leveraging AI as a key transformative agent. | $250K – $1M | 51 | N/A | 2mo | N/A | N/A |
| 2 | ▶ New Enterprise Associates (NEA) NEA partners with ambitious founders at every stage of company building, from pre-seed through IPO. They invest at the intersection of technology and healthcare, believing the most transformational innovation occurs where deep domain expertise meets world-class technical founders. NEA serves as both capital provider and active operator. Menlo Park | $1M – $50M | 26 | Both | Active | ~2 mo | Open |
| 3 | ▶ Antler Backing exceptional people at the very start of their journey. We support founders from inception to scale through our global residency programs, providing capital, mentorship, and access to a network of 1,500+ companies across six continents. | $125K – $500K | 31 | Leads | Active | ~2 wks | Open |
| 4 | ▶ DeVC Back relentlessly resourceful founders with capital, wisdom, and networks from a collective of 50+ operators who have built and scaled companies like CRED, Haptik, Park+, OfBusiness, Razorpay, and Swiggy, favoring ground-reality operating experience over trend-chasing. Bengaluru, India | $50K – $500K | 26 | Follows | Active | N/A | N/A |
| 5 | ▶ Expa We build category-defining companies through a combination of design, product, operations, and capital. We identify market gaps, pair brilliant founders with Expa's studio resources, and help them build companies that reshape entire industries. San Francisco | $500K – $5M | 60 | Leads | Active | ~1 wk | Open |
| 6 | ▶ SEGO Venture Channel capital from a large base of retail and institutional investors into vetted, growth-stage Spanish companies with strong public narratives, giving individual investors direct equity access normally reserved for institutional VC. Madrid | $300K – $10M | 11 | N/A | Active | N/A | N/A |
| 7 | ▶ TheoryForge Operator-led fund investing in ambitious founders building transformative AI applications. We partner with technical founders who understand AI/ML deeply and are solving real customer problems with capital efficiency. Great product is always the best marketing. | $200K – $500K | 38 | Both | Active | ~2 wks | Req'd |
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Firms that frequently co-invest with investors on this page
F4 Fund tracks 7 VC firms that actively invest in travel & hospitality + biotech & life sciences. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for travel & hospitality + biotech & life sciences investors is $625K – $625K, with a full range from $50K – $50M. The distribution breaks down as: 3 firms in the <$500K range, 1 firms in the $500K-$1M range, 1 firms in the $2M-$5M range, 1 firms in the $5M-$10M range, 1 firms in the $10M+ range.
Among the 7 firms tracked, 57% lead or co-lead rounds, and 14% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best travel & hospitality + biotech & life sciences investors combine domain expertise with an active portfolio in the space. Among these firms, 25% prefer warm introductions, and the average firm has 35 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.