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#45 · Biotech 50 · 2026

Decheng Capital

decheng.com · Menlo Park, CA

“Decheng Capital provides capital and strategic support to early-stage life science companies with revolutionary technologies and growth-stage healthcare companies with strong market presence, capitalizing on the rapid growth of the healthcare industry and breakthroughs in life science research. A cross-border US-China network and dealflow advantage differentiates the firm.”

$5M – $20M
Check Size
Leads
Lead Tendency
$2.5B
AUM
01Investment Thesis

Decheng Capital provides capital and strategic support to early-stage life science companies with revolutionary technologies and growth-stage healthcare companies with strong market presence, capitalizing on the rapid growth of the healthcare industry and breakthroughs in life science research. A cross-border US-China network and dealflow advantage differentiates the firm.

Exclusion Criteria

Not a generalist tech investor; focused exclusively on life sciences, biopharma, diagnostics, medical devices, and healthcare services.

02Investment Team
MC
Min Cui
Founder and Managing Director
VT
Victor Tong, Jr.
Managing Director
PC
Peter Colabuono
Managing Director
DM
Dayton Misfeldt
Partner
TT
Tony Tong
Partner
QX
Qiang Xu
Partner
WX
Wei Xu
Partner
AL
Aaron Li
Principal
SJ
Shengyang Jin
Vice President
MN
Michael Notaras
Vice President
JC
Joan Chen
Vice President
CZ
Claire Zhang
Senior Associate
NP
Nick Pliam
Venture Partner
03F4 Research Brief

Decheng Capital Research

Investment Thesis

Decheng Capital is a global life sciences investment firm founded in 2012 and headquartered in Menlo Park, CA, with additional offices in Shanghai and New York. The firm describes its mission as providing capital and strategic support to early-stage life science companies with revolutionary technologies and growth-stage healthcare companies with strong market presence. Decheng's stated thesis is to capitalize on the rapid growth of the healthcare industry and breakthroughs in life science research, positioning itself as a "preferred partner for entrepreneurs, world-class scientists and strategic partners." A defining feature of the firm's strategy is a cross-border focus, leveraging deep networks and market access in both the United States and China to source and support healthcare and life science companies.

Stage Focus

Decheng invests across the company lifecycle, from early-stage private rounds (seed, Series A) through growth equity and into public-market follow-on investing (the portfolio includes numerous companies the firm backed pre-IPO and continued to hold or add to post-listing). The firm is comfortable investing in companies with "revolutionary technologies" pre-revenue as well as growth-stage healthcare businesses that already have commercial traction.

Check Size

No explicit check-size range is published on the firm's site. Third-party coverage describes the firm's range as spanning pre-seed to growth equity, consistent with a multi-stage life sciences generalist. Existing F4-OS records show a working range of roughly $5M-$20M per investment, which is a reasonable mid-range estimate for a firm of this AUM but should be treated as a moderate-confidence estimate absent a primary-source figure.

Lead Tendency

Decheng frequently leads or co-leads syndicates. Most recently, Decheng led the ~$100M private placement financing for Remix Therapeutics (announced June 24, 2026, ahead of its reverse merger with Passage Bio and Nasdaq listing as RMTX), with participation from Lynx1 Capital Management, Forge Life Science Partners, and other investors. This lead role is consistent with the firm's pattern in earlier rounds like Aardvark Therapeutics' oversubscribed $85M Series C.

Recent Activity

Decheng has been actively deploying, with 2 new investments in 2025 and 2 more logged as of March 2026, and its most recent disclosed investment (Remix Therapeutics) closing in June 2026. The firm is simultaneously in market with its fifth flagship fund, Decheng Capital Global Life Sciences Fund V, targeting $700M (larger than the $650M target for its 2020-vintage predecessor fund); as of an October 2025 SEC filing, the fund had raised roughly $450M toward that target, indicating the fund is still actively fundraising and deploying rather than fully closed.

Portfolio Highlights

Decheng's portfolio spans roughly 80+ companies with a strong exit track record: 18+ IPOs and 19+ acquisitions, including marquee names like Invitae, Adaptive Biotechnologies, and GRAIL (acquired by Illumina). Standout recent exits include Prometheus Biosciences (acquired by Merck for $10.8B, closed June 2023) and Alpine Immune Sciences (acquired by Vertex Pharmaceuticals for ~$4.9B, announced April 2024). Other notable active portfolio companies include Mammoth Biosciences (CRISPR gene editing, with a $100M upfront Regeneron collaboration), Cellares (automated cell therapy manufacturing, with a $380M Bristol Myers Squibb supply deal), Upstream Bio, Hummingbird Bioscience, Mirvie, and Shape Therapeutics.

Team

  • Min Cui, Ph.D. — Founder and Managing Director
  • Victor Tong, Jr. — Managing Director
  • Peter Colabuono — Managing Director
  • Dayton Misfeldt — Partner
  • Tony Tong, Ph.D. — Partner
  • Qiang Xu, Ph.D. — Partner
  • Wei Xu — Partner
  • Aaron Li, MBA — Principal
  • Shengyang Jin, Ph.D. — Vice President
  • Michael Notaras, Ph.D. — Vice President
  • Joan Chen, Ph.D. — Vice President
  • Claire Zhang, M.B.A. — Senior Associate
  • Nick Pliam, M.D., Ph.D. — Venture Partner

The firm's site does not publish individual bios, prior-firm history, or LinkedIn URLs, so founder-facing background beyond name, title, and academic credentials is not independently verifiable from the primary source.

Decision Process

With a partner-level team of this size (7 partners/MDs plus a bench of VPs and principals), Decheng operates as a partnership rather than a solo-GP shop. No public detail on decision timeline was found.

Founder Preferences

Decheng backs founding teams built around "revolutionary technologies," which in practice skews toward scientist-founders and academic spinouts (e.g., CRISPR platforms, novel modalities) as well as experienced healthcare operators building growth-stage commercial businesses. The firm's cross-border network makes it a natural fit for founders with US-China commercialization ambitions.

Geographic Focus

Primary geography is the United States (Silicon Valley HQ) and China (Shanghai office), with a New York office supporting East Coast biotech and capital-markets relationships. The firm explicitly positions cross-border US-China dealflow and market access as a differentiator.

04Selected Portfolio
Biotech & Life Sciences
Mammoth Biosciences·Cellares·Upstream Bio·Prometheus Biosciences·Adaptive Biotechnologies·Alpine Immune Sciences·Arcus Biosciences·Grail·CG Oncology·Zentalis Pharmaceuticals·Terns Pharmaceuticals·Everest Medicines·Remix Therapeutics·Scynexis·Acelyrin·Aadi Bioscience·Hummingbird Bioscience·Shape Therapeutics·Watchmaker Genomics·Firefly Bio·KeChow Pharma·AnHeart Therapeutics·Aardvark Therapeutics
Healthcare & Digital Health
Invitae·Nalu Medical·Cue Health·Mirvie
Open the full portfolio→
05Recent Updates

Fresh signals from public announcements, essays, and portfolio activity.

See full activity (12) →
Led a ~$100M oversubscribed private placement in Remix Therapeutics ahead of its reverse merger with Passage Bio and Nasdaq listing as RMTX.
INVESTMENT·globenewswire.com
JUN 24, 2026
Targeting $700M for its fifth flagship life sciences fund, larger than the $650M target for its 2020-vintage predecessor.
NEW FUND·dealstreetasia.com
OCT 6, 2025
Aardvark Therapeutics announced an oversubscribed $85M Series C financing.
INVESTMENT·decheng.com
MAY 9, 2024
Mammoth Biosciences signed a gene-editing collaboration with Regeneron worth $100M upfront.
MILESTONE·decheng.com
APR 25, 2024
Cellares signed a $380M CAR-T cell therapy manufacturing supply deal with Bristol Myers Squibb.
MILESTONE·decheng.com
APR 22, 2024
06Frequent co-investors
FC
Foresite Capital
Both backed 3 of the same companies
Grail, CG Oncology, Mammoth Biosciences
CC
Casdin Capital
Both backed 2 of the same companies
Adaptive Biotechnologies, Invitae
OF
Omega Funds
Both backed 2 of the same companies
Alpine Immune Sciences, Upstream Bio
SB
Samsara BioCapital
Both backed 2 of the same companies
Upstream Bio, Acelyrin
SA
SV Angel
Both backed 2 of the same companies
Grail, Mammoth Biosciences
Find the investors for your round→
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RV
Roche Venture Fund
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JC
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Quick Reference
Check Size
$5M – $20M
Stages
Seed · Series A
AUM
$2.5B
Decision
Partnership
Location
Menlo Park, CA
Sector Focus
Biotech & Life SciencesHealthcare & Digital Health
Models
BiopharmaDiagnosticsMedical DevicesHealthcare ServicesB2B
Technology
Gene EditingCell Therapy ManufacturingGenomics
See all Biotech & Life Sciences investors →See all Healthcare & Digital Health investors →
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Focus Areas
Biotech & Life SciencesHealthcare & Digital Health

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F4 Intelligence Report · Last Researched September 1, 2026F4 Research Engine