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Hike Ventures

hikevc.com · San Francisco, CA

Investment thesis

LLMs have learned the public internet; the next frontier is private, operational context. Back seed-stage AI startups with proprietary data born in real-world operations, plus the AI-native execution layer for agents.

01Investment Thesis

LLMs have learned the public internet; the next frontier is private, operational context. Back seed-stage AI startups with proprietary data born in real-world operations, plus the AI-native execution layer for agents.

02Investment Team
MY
Mikihiro Yasuda
General Partner (San Francisco)
TS
Taka Shoji
General Partner (Tokyo)
03F4 Research Brief

Hike Ventures Research

Investment Thesis

Hike Ventures is a seed-stage venture firm investing in AI startups across North America, run from San Francisco and Tokyo. It has invested in AI since 2018. The stated thesis is that large language models have learned the public internet, and the next frontier is private, operational context: proprietary data created in real-world operations, customer workflows, and industry-specific environments. The firm says it backs startups that solve real-world problems with proprietary data, not foundation models themselves. Its founding principle is "Algorithm + Human > Algorithm or Human": it prefers companies where AI amplifies people rather than replacing them.

The site frames two themes. The first is AI built on operational data, with examples such as radiology images (Rad AI), wildfire frontlines (BurnBot), ship decks (ShipIn), farms (Greeneye), ICUs (Calmwave) and police patrols (Barricade). The second is the AI-native execution layer: verification, integration, permissions and operations that let AI agents execute work safely and continuously.

Stage Focus

Seed stage, per the site header ("Seed-stage AI, North America"). Several portfolio companies are shown going from seed to Series A, B or C with Hike staying in, so the firm appears to follow on in winners. No explicit check size is published; none is claimed here.

Check Size

Not disclosed on the website. Left blank rather than inferred.

Lead Tendency

Not stated. Recorded as unknown.

Recent Activity

The firm's news page lists four items in 2026, all portfolio milestones rather than new Hike investments:

  • Oct 2026: Charter Space announced a $5M seed round for space-industry insurance.
  • Aug 2026: Matic Robots launched Matic Cues voice and gesture control for its home cleaning robot.
  • Aug 2026: ShipIn Systems raised $52M for its AI platform for commercial shipping, deployed on 1,300+ vessels.
  • May 2026: Human Archive raised $8.2M for human work data for physical AI, with 1,000+ headsets deployed.

The site says it has run three funds. Fund sizes and the current fund status are not published, so fund status is recorded as unknown.

Portfolio Highlights

The site claims 70+ portfolio companies in total and lists 57 organized by theme. Highlights called out on the homepage are Rad AI (Fund I, seed to Series C; used by over 55% of the U.S. radiology market), Matic (Fund I, seed through Series A+), and Mesh (Fund II, seed to Series C; crypto and stablecoin payment interconnect supporting Google's AP2). Marked exits on the portfolio page are Medmain, Pitstop, Konnecto, Percept.AI and Readlee. Other named companies include Calmwave, Legion Health, BurnBot, Greeneye, Paladin, Barricade, Ragas, Botpress, Cekura, Firmly, Antigen and Cyberdesk.

Portfolio themes: Healthcare (11), Physical and Operational World (16), Money and Commerce (7), Creative Work (3), AI Stack (11), and AI-Native Applications (9).

Team

  • Mikihiro Yasuda, General Partner, San Francisco. Started as a programmer at Netscape Japan, then board member, CTO and COO of Kakaku.com. Later board member at Digital Garage, CEO of Open Network Lab, and head of DeNA's Silicon Valley investment team. Co-founded Hike Ventures. Board member of UCSF Health Hub.
  • Taka Shoji, General Partner, Tokyo. Worked on search products at Baidu Japan, then helped U.S. startups enter Japan at Digital Garage. Managing Director of DG Incubation, leading seed investing across North America and Asia. Co-founded MUSIC FOR MUSIC, then co-founded Hike Ventures.

Decision Process

Two general partners who co-founded the firm. The process is not described publicly; recorded as partnership.

Founder Preferences

Founders with access to data the internet cannot see, built through trust and repeated interaction with customers and industries. The GPs say they understand the value of operational data because they come from the operating side as programmers, product managers and company builders.

Limited Partners and Geography

Hike is backed by Japanese corporations and financial institutions and offers LPs monthly briefings, working sessions, deal and PoC sourcing, and San Francisco ecosystem access. Investments target North America; the firm operates between San Francisco and Tokyo, and a few portfolio companies are Tokyo-based (X-Locations, UPBOND, 6over3).

04Selected Portfolio
AgTech & Agriculture
Greeneye
Biotech & Life Sciences
Phenomic AI·Pragma Bio·CYTK·Antigen
Climate & Sustainability
Burnbot
Consumer Apps & Social
Readlee
Crypto & Web3
UPBOND
Developer Tools & Infrastructure
Ragas
E-commerce & Marketplaces
Nectar·Defog
Enterprise Software
ShipIn·Barricade·Ethosphere·InspectMind·X-Locations Inc.·Charter Space·Pitstop·Truewind·Shuffll·BeatDapp·Cekura·Botpress·MLTwist·Typewise·Salmon Labs·Futurepath AI·6over3·Tradespace·Percept.ai
Fintech & Payments
Balance·Photon Commerce
Food & Beverage
Chef Jasper·Nowadays
Healthcare & Digital Health
Rad AI·CalmWave·Legion Health·Preemptive·MedMain·Optina Dx·Kangaroo Health·Petal Surgical·Cura.fi
Legal & Regtech
Cognition IP
Marketing & Adtech
Konnecto
Media & Entertainment
Intangible
Real Estate & PropTech
Swiftlane
Robotics & Automation
Matic·EverestLabs
Security & Cybersecurity
Mesh·LoginID·Oort·CyberDesk
Semiconductors & Hardware
Subtle
Other
Paladin·Doorvest·Firmly
Open the full portfolio→
05Recent Updates

Fresh signals from public announcements, essays, and portfolio activity.

Portfolio company Charter Space announced a $5M seed round to expand space insurance, serving 50+ U.S. space and defense companies.
MILESTONE·hikevc.com
OCT 1, 2026
Portfolio company Matic Robots launched Matic Cues voice and gesture control, covered by The Verge and Bloomberg.
MILESTONE·hikevc.com
AUG 14, 2026
Portfolio company ShipIn Systems raised $52M for its commercial shipping AI platform, deployed on 1,300+ vessels.
MILESTONE·hikevc.com
AUG 4, 2026
Portfolio company Human Archive raised $8.2M for human work data for physical AI, with 1,000+ headsets deployed.
MILESTONE·hikevc.com
MAY 26, 2026
06Frequent co-investors
AI
Allen Institute for AI (AI2) Incubator
Both backed 3 of the same companies
Preemptive, Ethosphere, CalmWave
RV
Real Ventures
Both backed 3 of the same companies
Nectar, Chef Jasper, Botpress
AV
AIN Ventures
Both backed 2 of the same companies
Tradespace, MLTwist
A
Ascend
Both backed 2 of the same companies
Mesh, Preemptive
H
Hawktail
Both backed 2 of the same companies
Burnbot, Matic
Find the investors for your round→
Quick Reference
Stages
Seed
Decision
Partnership
Location
San Francisco, CA
Sector Focus
Fintech & PaymentsBiotech & Life SciencesRobotics & AutomationEnterprise SoftwareDeveloper Tools & InfrastructureSecurity & CybersecurityHealthcare & Digital HealthLegal & Regtech
Models
Proprietary-Data AIVertical AIAI Agent Infrastructure
Technology
AI/MLLLMComputer VisionRobotics
See all Fintech & Payments investors →See all Biotech & Life Sciences investors →See all Robotics & Automation investors →
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Focus Areas
Fintech & PaymentsBiotech & Life SciencesRobotics & AutomationEnterprise SoftwareDeveloper Tools & InfrastructureSecurity & CybersecurityHealthcare & Digital HealthLegal & Regtech

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F4 Intelligence Report · Last Researched November 6, 2026F4 Research Engine