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Polytechnique Ventures

polytechnique-ventures.fr · Paris, France

Investment thesis

Alumni-funded seed fund backing ambitious deep tech start-ups from the École polytechnique ecosystem: alumni-founded, lab spin-outs or incubated at the School.

$50K – $1M
Check Size
Leads & Follows
Lead Tendency
01Investment Thesis

Alumni-funded seed fund backing ambitious deep tech start-ups from the École polytechnique ecosystem: alumni-founded, lab spin-outs or incubated at the School.

Exclusion Criteria

Companies with no tie to the École polytechnique ecosystem are not the focus.

02Investment Team
DL
Denis Lucquin
Founder & Chairman
CT
Cécile Tharaud
Managing Partner
MC
Maxime Cardinal
Partner
GD
Gaspard Devissaguet
Principal
MD
Marius Dissler
Analyst
RE
Raphaëlle Ezeghian
Analyst
03F4 Research Brief

Polytechnique Ventures Research

Investment Thesis

Polytechnique Ventures is the alumni-funded seed fund of the École polytechnique. It invests in start-ups that come out of the School's innovation and entrepreneurship ecosystem: companies founded by one or more alumni (engineering degree, Bachelor, Master, Exed or PhD), companies incubated at the School (incubator, nursery, prototyping lab), and companies spun out of the School's laboratories. The stated priority is ambitious deep tech teams able to transform the industrial sectors they target. Selection criteria are the quality of the founding team, the uniqueness of the technology, the company's development potential and its societal contribution.

Stage Focus

The fund finances pre-seed, seed and Series A companies. Its main strategy is seed and Series A. A side strategy, the Denis Lucquin Catalyst Initiative, is dedicated to pre-seed. It tries to follow on in later rounds and can exceptionally join a Series B.

Check Size

The firm's own FAQ gives two ranges:

  • Pre-seed (Denis Lucquin Catalyst Initiative): EUR 50K to EUR 200K
  • Seed and Series A: EUR 500K to EUR 1M
  • Follow-on capacity up to EUR 3M invested per company in total

Third-party profiles describe initial tickets of EUR 250K to EUR 1M for Fund II; the website figures are used for the structured fields.

Lead Tendency

The fund prefers co-investing alongside professional early-stage VCs. It does not rule out leading, but says leading is not its first vocation. A Jimini co-founder's testimonial on the homepage says the fund led Jimini's seed round, so the lead tendency is recorded as both.

Recent Activity

Fund I (EUR 36M) made 18 investments. Fund II is raising: a EUR 21M first close was reported, and a later report puts it at about EUR 28M against a EUR 30M to EUR 40M target, to back 15 to 20 start-ups. Recent portfolio entries listed on the site include Gobano Robotics (pre-seed, April 2025), BYoRNA (pre-seed, March 2025), OneBiosciences (Series A, May 2025) and VSora (Series A, May 2025). Fund status is treated as actively deploying.

Portfolio Highlights

The portfolio page lists 21 companies across energy, biotech, robotics, semiconductors, AI and cleantech: Airthium (high-temperature heat pumps), BYoRNA (in vivo mRNA production), Docent (AI art platform), Galam Robotics (urban automated storage), Gobano Robotics (imitation-learning robots), Goodvest (Paris-aligned savings), H Company (AI agents), Hyperplan (agri supply analytics), Jimini (legal AI), Jimmy Energy (HTR microreactors for industrial heat), Mirsense (lasers and sensing), Mithril Security (confidential AI), Néolithe (waste to aggregates), Okomera (precision oncology chips), OneBiosciences (single-cell oncology AI), Pact (collagen leather), Qivia (mobility payments), Reev (robotic knee orthosis), Spinergie (maritime analytics), Verra (strategy AI) and VSora (AI inference chips).

Team

  • Denis Lucquin, Founder and Chairman (X77): 17 years at Sofinnova Partners, including 10 as its Chairman; founded France Biotech; initiated Inserm Transfert Initiative. Serves without pay.
  • Cécile Tharaud, Managing Partner (X84): ex-pharma and biotech operator, rebuilt Inserm's technology transfer arm and raised EUR 35.5M for Inserm Transfert Initiative; PhD and INSEAD MBA.
  • Maxime Cardinal, Partner (X2010): eight years in innovation and international roles at EDF, energy access investments.
  • Gaspard Devissaguet, Principal: previously Demeter Partners and Bpifrance.
  • Marius Dissler, Analyst (X2022).
  • Raphaëlle Ezeghian, Analyst: previously Bpifrance and AstraZeneca.

Decision Process

The team decides with the help of an advisory committee of VC professionals (ISAI, Auriga Partners, Iris Capital, Tikehau Capital, Seven2, Partech Impact) that meets start-ups under consideration, and a strategic committee that oversees conflicts of interest and investment policy. Decision process is recorded as partnership.

Founder Preferences

Founders tied to the School: alumni, lab spin-outs or incubated teams, with differentiated technology and ambitious strategies. The fund offers campus access, the incubator and Fab Lab, an alumni mentor network and early-stage financing rigor. Half of the team's carried interest goes to the École polytechnique Foundation.

Geographic Focus

France and Europe first, but start-ups based elsewhere are possible if tied to the School. The fund is managed by IQEQ Management and based at 12 rue de Poitiers, Paris.

Gaps

The site's news page was too large to read in full and was not used. Assets under management are not stated on the site and are left unset because the two funds are in euros and the fund II size is still moving. Portfolio company domains were not resolved except VSora.

04Selected Portfolio
AgTech & Agriculture
Hyperplan
Biotech & Life Sciences
BYoRNA·Okomera·OneBiosciences
Climate & Sustainability
Airthium·Néolithe
Energy & Power
Jimmy Energy·reev
Enterprise Software
H·mirSense·Pact·Spinergie·Verra
Fintech & Payments
Goodvest
Healthcare & Digital Health
Docent
Legal & Regtech
Jimini
Logistics & Supply Chain
Galam Robotics
Mobility & Transportation
Qivia
Robotics & Automation
Gobano Robotics
Security & Cybersecurity
Mithril Security
Semiconductors & Hardware
VSORA
Open the full portfolio→
05Recent Updates

Fresh signals from public announcements, essays, and portfolio activity.

Fund II stood at about EUR 28M and dedicates a share to pre-seed deep tech start-ups.
NEWS·app.dealroom.co
Added recently
Raised EUR 21M for Fund II, targeting a final close of EUR 30-40M.
NEW FUND·sifted.eu
Added recently
Announced the final closing of its first early-stage fund at EUR 36M.
NEW FUND·polytechnique.edu
Added recently
06Frequent co-investors
AC
Auriga Cyber Ventures
Both backed 2 of the same companies
H, Mithril Security
OC
Omnes Capital
Both backed 2 of the same companies
VSORA, Jimmy Energy
SC
Serena Capital
Both backed 2 of the same companies
Goodvest, H
SI
Supernova Invest
Both backed 2 of the same companies
Galam Robotics, mirSense
X
XAnge
Both backed 2 of the same companies
VSORA, mirSense
Find the investors for your round→
07Similar Firms
DC
Divergent Capital
$250K – $1M · Pre-Seed · Seed
→
VV
Valo Ventures
$2M – $10M · Seed · Series A
→
FP
Future Planet Capital
Pre-Seed · Seed
→
NV
Norrsken VC
$1M – $10M · Seed · Series A
→
C
Cantos
$400K – $1.5M · Pre-Seed · Seed
→
Quick Reference
Check Size
$50K – $1M
Stages
Pre-Seed · Seed · Series A
Decision
Partnership
Warm Intro
Not Required
Location
Paris, France
Sector Focus
Biotech & Life SciencesSemiconductors & HardwareRobotics & AutomationClimate & SustainabilitySecurity & CybersecurityEnergy & PowerHealthcare & Digital Health
Models
Deep TechUniversity Spinouts
Technology
AI/MLRoboticsSemiconductorsBiotechEnergy Tech
See all Biotech & Life Sciences investors →See all Semiconductors & Hardware investors →See all Robotics & Automation investors →
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Focus Areas
Biotech & Life SciencesSemiconductors & HardwareRobotics & AutomationClimate & SustainabilitySecurity & CybersecurityEnergy & PowerHealthcare & Digital Health

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F4 Intelligence Report · Last Researched November 6, 2026F4 Research Engine