29 VC firms investing in food & beverage and biotech & life sciences at the Series A stage.
F4 Fund tracks 29 VC firms that actively invest in food & beverage + biotech & life sciences at the Series A stage, with check sizes ranging from $20K – $100M (median: $2.5M – $2.5M). As of June 2026, and 93% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,358+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Big Idea Ventures Solving the world's biggest challenges by supporting the world's best entrepreneurs in food and agriculture. Focus on sustainable, scalable solutions to global food security through innovation in alternative proteins, ingredients, and food technology. New York | $125K – $2M | 33 | Leads | Active | ~2 wks | Open |
| 2 | ▶ Digitalis Ventures Complex health problems require multidisciplinary teams combining deep technical, financial, and domain expertise. We invest in breakthrough science and technology-enabled solutions across human and animal health. New York | $250K – $50M | 54 | Leads | Active | ~2 mo | Req'd |
| 3 | ▶ Stray Dog Capital Explicitly structured to eliminate animals from food supply chain. Invests in innovative early-stage companies across food, beverage, and biotech driving healthier, humane, sustainable future. Optimizes for impact on animal numbers alongside commercial success. Leawood, Kansas | $100K – $1M | 22 | Leads | Active | ~2 wks | Req'd |
| 4 | ▶ Cultivian Sandbox Ventures Building next-generation food and agriculture technology companies that commercialize solutions for sustainable production, equitable distribution, and healthy consumption. Partners with strategic investors to drive systemic impact in food systems. Chicago | $1M – $10M | 21 | Both | Active | ~2 mo | Open |
| 5 | ▶ Humboldt Fund Apply revolutionary biotechnology to replace industrial inputs with biology-based alternatives, transforming how the world manufactures chemicals, materials, foods, and medicines. Synthetic biology is a $25T opportunity spanning industrial inputs, food & agriculture, pharmaceuticals, and specialized applications. New York | $500K – $2M | 19 | Both | Active | ~1 mo | Req'd |
| 6 | ▶ Acre Venture Partners Driving positive, lasting change in food and agriculture creates exceptional financial outcomes. Impact and return aren't trade-offs—they're intertwined. Both are essential. We invest in technologies and companies addressing human health, planetary well-being, responsible production, and climate solutions. Santa Monica | $500K – $5M | 29 | Leads | Active | ~1 mo | Req'd |
| 7 | ▶ DBL Partners Top-tier venture capital returns alongside meaningful social, environmental, and economic impact — the Double Bottom Line — with no tradeoff. DBL invests in mission-driven founders across clean energy, agriculture, nature-based solutions, health, economic opportunity, mobility, and the space/Earth nexus. San Francisco | $2M – $50M | 46 | Leads | Active | ~2 mo | — |
| 8 | ▶ Bluestein Ventures We invest in the future of food — backing game-changing early-stage ventures (Pre-Seed to Series A) that redefine how consumers achieve health and wellness across the entire food value chain: high-growth consumer brands, proprietary foodtech, next-gen commerce, and value-add digital technology. Fund III ($45M, 2024) emphasizes nutrition, sustainability, and digitization, with a thematic focus on food-as-medicine. Chicago | $250K – $5M | 37 | Leads | Active | — | — |
| 9 | ▶ Babel Ventures Biology is the next frontier of technology. BABEL believes early-stage consumer biotech can solve macro problems (food security, climate, health) while delivering outsized returns. The best outcomes come from diverse, science-credentialed founder teams with deep domain expertise and commitment to sustainability and impact. San Francisco | $100K – $3M | 19 | Leads | Active | ~2 wks | Req'd |
| 10 | ▶ AgFunder Progress in food, agriculture, and human health lags other sectors due to structural constraints. We invest in deep technologies that remove these bottlenecks at scale—whether AI, biology, robotics, or materials science. We're not intimidated by threats to the status quo. Silicon Valley | $500K – $5M | 34 | Both | Active | ~1 mo | Open |
| 11 | ▶ Collab Fund Investing at the intersection of for-profit and for-good. Companies that make the world better AND deliver strong financial returns. The Villain Test ensures both impact and profit alignment. New York | $500K – $10M | 44 | Leads | Active | ~2 wks | Open |
| 12 | ▶ Ataraxia VC Fund companies that help people live longer and live better through science and technology. We support exceptional technical founders solving real health and happiness problems with scientific rigor and consumer appeal. Our data-driven methodology and proprietary ML platform identify outsize return potential in complex early-stage companies. San Francisco | $500K – $5M | 11 | Both | Active | ~2 wks | Open |
| 13 | ▶ Prelude Ventures Climate is the biggest challenge of our lifetime and the greatest business opportunity of the coming decades. We back visionaries accelerating climate innovation that will reshape our global economy for the betterment of people and planet. The most successful companies are born from a vision for a better future and the ability of that vision to create large, lasting positive impact. We invest in frontier technologies addressing climate across seven sectors: Built Environment, Carbon Management, Compute, Energy, Food & Agriculture, Manufacturing & Industrials, and Mobility. The best ideas come from everywhere—we operate where many venture firms can't or won't. San Francisco | $100K – $5M | 51 | Both | Active | ~2 mo | Open |
| 14 | ▶ Lerer Hippeau As founder-operators, we see returns in relationships. We back ambitious founders with exceptional vision at the earliest stages with capital, mentorship, and network access. | $100K – $1M | 73 | Leads | Active | ~1 mo | Open |
| 15 | ▶ SoGal Ventures First women-led VC investing in underrepresented founders solving underserved problems in undercapitalized geographies. We capitalize on three biggest arbitrage opportunities: diversity of founders, geographic expansion beyond Silicon Valley, and problems with meaningful social impact. We back exceptional teams in consumer tech, digital health, and future of work sectors. New York | $250K – $2M | 16 | Leads | Active | ~2 wks | Open |
| 16 | ▶ FTW Ventures The $12 trillion food and agriculture industries still rely on centuries-old methods. We back disruptive science and technology to modernize the food system—from biotech and sensors to automation and software—to feed 10 billion people by 2050 while preserving nature and nurturing humankind. San Francisco | $500K – $5M | 24 | Leads | Active | ~2 mo | Req'd |
| 17 | ▶ E2JDJ Entrepreneurship × Exponential Growth. We back visionary founders solving systemic inefficiencies across the food and agriculture value chain. Our co-founders combine operational expertise (Providence growth equity, White House service, corporate law) with deep commitment to founder success. San Francisco | $100K – $3M | 14 | Leads | Active | ~2 wks | Req'd |
| 18 | ▶ Manta Ray Back mission-driven founders addressing significant global challenges through leading-edge technology. Provide flexible and patient capital, leveraging our time, resources, and networks to support portfolio company success. Focus on founders with authentic social and environmental missions alongside commercial viability. London | $250K – $3M | 55 | Both | Active | ~1 mo | Open |
| 19 | ▶ 1955 Capital Invest in advanced technologies solving the world's greatest challenges in energy, environment, food safety, sustainable manufacturing, healthcare, and education. Back contrarian founders building capital-intensive, deep-tech ventures that address survival-driven global needs. Bridge breakthrough technologies from developed markets into emerging economies and vice versa. Create high-return, high-impact outcomes through hard technology. Los Altos, California | $5M – $10M | 11 | Leads | Active | ~2 mo | Req'd |
| 20 | ▶ BoxOne Ventures Back passionate, emerging talent solving deep technology challenges. Support founders from napkin-stage through IPO with patient, flexible evergreen capital. Focus on biotechnology, frontier software, food innovation, longevity, and AI that maximize impact and potential. Montreal | $100K – $5M | 17 | Both | Active | ~2 mo | Open |
| 21 | ▶ The Helm Women receive only 2% of venture capital despite female-founded startups delivering 2x return per dollar vs. all-male teams. The Helm invests in game-changing, undervalued companies at seed stage founded by women, providing not just capital but operational support and ecosystem access. New York | $250K – $1.5M | 26 | Leads | Active | ~2 wks | Open |
| 22 | ▶ Snatched Ventures Backs DeepTech startups at the intersection of AI/ML, materials science, advanced manufacturing, biotechnology, optics, electronics, robotics, and blockchain — driving sustainable operational transformation across six thematics: transportation & logistics, energy & water, food & agriculture, fashion & beauty, precision medicine & aging, and retail & e-commerce. Requires commercial traction (min $1M revenue, 50%+ gross margins) and a minimum 10% ownership stake. San Francisco | $500K – $5M | 25 | Leads | Active | — | — |
| 23 | ▶ SVG Ventures We back bold founders and AI-enabled, game-changing innovations that improve planetary and population health. We target capital-efficient, highly scalable startups reimagining sectors like agri-food, climate, fintech, life sciences and nutrition through deep tech and proprietary IP. We engineer outcomes through operational support, strategic partnerships, and sector expertise. Los Gatos, California | $500K – $100M | 16 | Both | Active | ~2 mo | Req'd |
| 24 | ▶ Debut Capital Early-stage venture capital for IT and Biotech companies in Colorado Front Range and Mid-Atlantic. Focus on experienced founding teams solving important problems with potential for significant financial returns. Patient capital approach with operational support and deep regional networks. New York | $500K – $5M | 48 | Leads | Active | ~2 wks | Req'd |
| 25 | ▶ Vast Ventures We invest in companies organized around five concrete objectives: improving worldwide health and happiness, promoting resource sustainability, increasing human potential and productivity, increasing knowledge/empathy/connectedness, and disrupting industries that resist these goals. We operate as both investors and company-builders, providing operational expertise and hands-on support far beyond capital. New York | $250K – $3M | 26 | Leads | Active | ~2 wks | Req'd |
| 26 | ▶ Noon Ventures We invest in proven, transformative technologies that have the potential to be industry-defining while driving meaningful impact on the climate and environment. We partner with founders as active co-developers, not passive investors. Copenhagen | $500K – $10M | 5 | Leads | Active | ~1 mo | Open |
| 27 | ▶ Elevate Ventures Elevate Ventures partners with innovation-driven founders to provide strategic capital, mentorship, and ecosystem access. Founded by a former founder (Governor Mitch Daniels), the firm believes the best founders exhibit grit, creativity, and coachability. They invest across all sectors and geographies but maintain primary focus on Indiana and Great Lakes Region entrepreneurs building cross-sector innovations. Indianapolis | $20K – $2M | 28 | Leads | Active | ~1 mo | Open |
| 28 | ▶ Creative Destruction Lab The primary constraint for seed-stage, science-based entrepreneurs is access to experienced business judgment. CDL provides objective-based mentoring from accomplished entrepreneurs, angels, and scientists to help founders prioritize tasks and de-risk their businesses. Toronto | $50K – $250K | 20 | — | 1mo | ~2 wks | Open |
| 29 | ▶ Levante Capital Invest in the most promising Southern European (primarily Italian) deep-technology companies across Advanced Manufacturing, Life Science, and Energy & Environment, and actively support their expansion into Asian markets (China, South Korea, Japan, South-East Asia). The fund uses a proprietary evaluation framework and a 'pull model' — companies must demonstrate genuine Asian market interest before investment. Milan, Italy | $500K – $3M | 8 | — | Active | ~2 mo | Open |
Investors on this page also frequently invest in these sectors
What other stages do these firms also invest in?
What other sectors do these firms also invest in?
F4 Fund tracks 29 VC firms that actively invest in food & beverage + biotech & life sciences at the Series A stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for series a food & beverage + biotech & life sciences investors is $2.5M – $2.5M, with a full range from $20K – $100M. The distribution breaks down as: 1 firms in the <$500K range, 3 firms in the $500K-$1M range, 9 firms in the $1M-$2M range, 9 firms in the $2M-$5M range, 4 firms in the $5M-$10M range, 3 firms in the $10M+ range.
Among the 29 firms tracked, 93% lead or co-lead rounds. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best series a food & beverage + biotech & life sciences investors combine domain expertise with an active portfolio in the space. Among these firms, 42% prefer warm introductions, and the average firm has 29 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.