13 VC firms investing in gaming and healthcare & digital health at the Series B stage.
F4 Fund tracks 13 VC firms that actively invest in gaming + healthcare & digital health at the Series B stage, with check sizes ranging from $200K – $350M (median: $13M – $13M). As of June 2026, and 92% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,358+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Atinum Investment Atinum Investment identifies and invests in companies solving fundamental problems through technology innovation and market disruption. The firm specializes in growth-stage startups and paradigm-shifting companies across diverse sectors. | $500K – $10M | 56 | Leads | Active | ~2 wks | Open |
| 2 | ▶ Makers Fund Backing builders of the future of interactive entertainment. We invest across games, content, platforms, and ecosystem technologies with conviction that visionary founders are driving transformation in how we play, watch, create, and live. | $500K – $5M | 158 | Leads | Active | ~2 wks | Open |
| 3 | ▶ Headline We invest in top founders everywhere building the next generation of technology companies. We provide capital, operational expertise, and a truly global platform to scale with hands-on support through specialized teams. | $2M – $50M | 51 | Leads | Active | ~2 wks | Open |
| 4 | ▶ Andreessen Horowitz Backing the builders of the next layer of computing across AI infrastructure, defense, biotech, and American dynamism. Former 'Software is Eating the World' thesis evolved to 'AI is Eating Software'. Partners with technical founders building foundation models, cloud systems, and infrastructure for the AI era. Menlo Park | $1M – $200M | 48 | Both | Active | ~2 wks | Open |
| 5 | ▶ Bling Capital The hardest thing in seed is finding product-market fit. We help you find it. If you already have product-market fit, we will help you scale. We partner with exceptionally ambitious founders for the long run and provide capital combined with operational expertise through our 100+ member Product Council. San Francisco | $500K – $3M | 33 | Leads | Active | ~2 mo | Open |
| 6 | ▶ IVP We supercharge growth in breakout companies, converting momentum into market dominance. We invest exclusively at Series B and beyond in companies that have achieved product-market fit and are ready to scale from millions to hundreds of millions in revenue. San Francisco | $1M – $25M | 31 | Leads | Active | ~2 mo | Req'd |
| 7 | ▶ Lightbox Early-growth brands that India will obsess over tomorrow — technology-led consumer businesses where product is the champion and tech a catalyst. Lightbox takes concentrated bets in select entrepreneurs and partners beyond capital through deep operational involvement. Mumbai | $5M – $30M | 20 | Leads | Slowing | ~2 mo | Open |
| 8 | ▶ Coatue The best investment opportunities emerge at the intersection of innovation and scale. We invest across the full lifecycle from seed to public markets, focusing on technology companies that will transform sectors globally with particular conviction in AI-enabled platforms and infrastructure. New York | $1M – $100M | 30 | Both | Active | ~2 wks | Open |
| 9 | ▶ HOF Capital HOF Capital invests in relentlessly ambitious founders building world-changing technologies that accelerate abundance: sustained technological progress that expands access to opportunity, health, and economic prosperity. Its current public thesis emphasizes AI and agentic systems as amplifiers of discovery, engineering, and knowledge creation, alongside frontier infrastructure and applications that can shorten scientific and technological invention timelines. New York | $500K – $10M | 29 | Both | Active | ~2 wks | Req'd |
| 10 | ▶ Goodwater Capital Consumer technology has the power to measurably improve billions of lives across the globe. We invest in exceptional entrepreneurs building digital utilities that provide better access to housing, healthcare, food, financial services, transportation, education, and entertainment globally. Burlingame, California | $5M – $50M | 29 | Leads | Active | ~1 mo | Req'd |
| 11 | ▶ Insight Partners Software founders need more than capital to scale successfully. Insight Partners combines investment capital with hands-on operational expertise, embedded teams, and network access to accelerate company growth across all stages. New York | $10M – $350M | 28 | Leads | Active | ~1 mo | Open |
| 12 | ▶ Gaingels Equity of access and representation in venture capital delivers positive returns. Diverse and underrepresented (including LGBTQ+) leaders of high-growth companies deserve capital access. When these founders succeed, they influence ecosystems and open doors for historically excluded groups. New York | $200K – $500K | 29 | Follows | Active | ~2 wks | Open |
| 13 | ▶ Evolution Venture Capital Partners Culture-Tech companies that disrupt and define how we live, work, play, and interact with the world every day. We invest in passionate founders building transformative products that change cultural behaviors. New York | $500K – $6M | 28 | Leads | Active | ~1 wk | Open |
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Firms that frequently co-invest with investors on this page
F4 Fund tracks 13 VC firms that actively invest in gaming + healthcare & digital health at the Series B stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for series b gaming + healthcare & digital health investors is $13M – $13M, with a full range from $200K – $350M. The distribution breaks down as: 1 firms in the <$500K range, 1 firms in the $1M-$2M range, 2 firms in the $2M-$5M range, 2 firms in the $5M-$10M range, 7 firms in the $10M+ range.
Among the 13 firms tracked, 92% lead or co-lead rounds, and 8% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best series b gaming + healthcare & digital health investors combine domain expertise with an active portfolio in the space. Among these firms, 23% prefer warm introductions, and the average firm has 44 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.