38 VC firms investing in insurance and healthcare & digital health at the Seed stage.
F4 Fund tracks 38 VC firms that actively invest in insurance + healthcare & digital health at the Seed stage, with check sizes ranging from $50K – $500M (median: $2.6M – $2.6M). As of June 2026, and 84% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,358+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ OCA Ventures We help bold, creative, and humble founders build great companies by providing hands-on operational support, strategic guidance, and valuable ecosystem connections. We specialize in fintech, insurtech, digital health, and enterprise software where we can add deep value beyond capital. Chicago | $1M – $3M | 74 | Both | Active | ~2 wks | Open |
| 2 | ▶ Core Innovation Capital The greatest returns come from the most overlooked markets where businesses outperform because they create value. We invest in early-stage technology companies that unlock wealth and health for the mass market — in massively regulated, operationally complex sectors that are broken and overdue for reinvention: financial services, healthcare, real estate, insurance, and work. Los Angeles | $1M – $5M | 66 | Leads | Active | ~1 mo | Req'd |
| 3 | ▶ Distributed Ventures Risk becomes opportunity when paired with the right capital. Distributed Ventures invests in early-stage companies transforming health, insurance, and wealth through technology, partnering with founders to provide not just capital but strategic guidance, distribution channels, and operational expertise. The firm's unique LP base of insurance carriers, wealth managers, and brokers creates direct customer access and validation opportunities. New York | $1M – $5M | 22 | Leads | Active | ~1 mo | Open |
| 4 | ▶ SixThirty We invest at the intersection of health, wealth, and privacy. The next generation of financial infrastructure, healthcare, and data security solutions will emerge from early-stage startups addressing this convergence. We partner with founders and leverage corporate LP relationships for distribution and go-to-market. St. Louis | $500K – $5M | 39 | Leads | Active | ~1 mo | Open |
| 5 | ▶ Abstract Ventures Backing transformative founders building exceptional companies across all sectors San Francisco | $100K – $1M | 275 | Both | Active | — | — |
| 6 | ▶ Tusk Venture Partners Early-stage technology companies operating in highly regulated markets can achieve extraordinary growth when founders understand how to turn regulatory and political risk into a competitive advantage. We provide not just capital but also political expertise and government relations support to help solve the regulatory gating issues that unlock growth. New York | $750K – $10M | 29 | Leads | Active | ~2 mo | Req'd |
| 7 | ▶ MS&AD Ventures MS&AD Ventures partners with visionary entrepreneurs to create innovative solutions across insurance, financial services, healthcare, and sustainability. Backed by the 5th largest global insurance conglomerate, they bring capital plus global distribution across 47 countries. They move fast (2-week decisions), focus on partnerships over ownership, and help companies scale internationally. Menlo Park | $500K – $5M | 57 | Both | Active | ~2 wks | Open |
| 8 | ▶ Mundi Ventures Mundi backs bold, purpose-driven founders building technology companies at the intersection of deep tech and critical global challenges. Core thesis: Europe has world-class talent and ecosystem but suffers from a scale-up funding gap at growth stages. Kembara fund (€750M) bridges this by providing Series B/C growth capital to European deep tech and climate champions. Madrid | $1M – $40M | 53 | Leads | Active | ~2 mo | Open |
| 9 | ▶ Montage Ventures Montage Ventures aims to support radical thinkers who are bringing new ideas and platforms to foster change within the financial services, commerce and health sectors, leveraging AI as a key transformative agent. | $250K – $1M | 51 | — | 2mo | — | — |
| 10 | ▶ Artem Ventures Investing in tomorrow's needs—promoting financial inclusion and social security for underserved communities through early-stage fintech, insurtech, and Islamic fintech. We enhance entrepreneurs' capacity to build sustainable, adaptable businesses and provide market access support, ESG mentoring, and operational advisory alongside capital. Kuala Lumpur | $250K – $1M | 13 | Follows | Active | ~2 mo | Open |
| 11 | ▶ Munich Re Ventures Funding the future of risk for the human endeavor. Munich Re Ventures invests in technologies and business models tackling the biggest risks facing the world, operating at the intersection of technology, venture capital, and the insurance industry. San Francisco | $500K – $10M | 20 | — | 2mo | ~2 mo | Req'd |
| 12 | ▶ Emergence Capital Emergence invests in early-stage B2B software companies that will define the next era of enterprise technology. Founded in 2003 as the original cloud/SaaS-focused VC firm, they have pioneered investing through technology transitions: horizontal SaaS (Salesforce, Zoom), vertical SaaS (Veeva, Doximity), and now AI-native services — companies that sell outcomes rather than software, powered by AI that compounds competitive advantage over time. San Francisco | $5M – $50M | 55 | Leads | Active | ~1 mo | Open |
| 13 | ▶ AltaIR Capital Back focused founders solving real problems in markets they understand deeply, with clarity, discipline, and drive. Seek companies with motivated teams, strong product vision, scalable business models, and large addressable markets. San Francisco | $1M – $25M | 40 | Leads | Active | ~1 mo | Open |
| 14 | ▶ MGV Top-performing SaaS venture fund that identifies exceptional founding talent at the earliest stages and takes an active role in their growth — particularly in scaling go-to-market and sales teams. Prioritizes founding team potential over traction or revenue metrics. San Francisco | $500K – $750K | 28 | Follows | Active | ~2 wks | Open |
| 15 | ▶ Vertical Venture Partners Back founders with deep, first-hand domain expertise in specific industry verticals — those who have 'lived' the problem they are solving. Vertical-first software delivers faster time-to-value and stronger retention versus horizontal tools requiring heavy customization. Palo Alto | $500K – $4M | 47 | Both | Active | ~1 mo | Open |
| 16 | ▶ Figure 8 Investments Catalyzing systemic change through investments in inclusive education, healthcare accessibility, and climate solutions linked to social mobility. Investment capital as a tool for systemic change when deployed with intentionality around expanding accessibility, reducing costs of essential services, breaking down geographic barriers, and building sustainable systems. Unique commitment to 10% profits-to-nonprofits creating a virtuous cycle of impact. Boulder, Colorado | $50K – $500K | 16 | Leads | Active | ~2 wks | Req'd |
| 17 | ▶ ATX Venture Partners Seeking early-stage alpha through institutional discipline. ATX VP invests in people pioneering the future by combining Wall Street rigor with deep operating experience. Core focus on disruptive B2B software, APIs, frontier tech, and marketplaces across Supply Chain, FinTech, InsurTech, HR Tech, Aerospace, and Future of Work. Austin | $250K – $5M | 42 | Leads | Active | — | Open |
| 18 | ▶ Elevar Equity Fund economic resilience of underserved entrepreneurial households through early-growth capital in businesses where impact and commercial performance are structurally aligned. Invest in companies democratizing access to essential products and services across financial inclusion, education, healthcare, agri-supply chains, and MSME solutions. Seattle | $1M – $2.5M | 23 | Leads | Active | ~2 mo | Open |
| 19 | ▶ AV8 Ventures Partner with visionary founders to build category-defining companies in healthcare, enterprise software, fintech/insurtech, and deep technology. Provide deep operational support, board participation, and access to domain expert network. Focus on companies solving problems in regulated or data-rich industries. Leverage Allianz's unique vantage point on risk, data, and regulation to identify opportunities at intersection of innovation and regulatory necessity. Palo Alto | $500K – $10M | 22 | Leads | Active | ~2 wks | Open |
| 20 | ▶ ResilienceVC Seed-stage embedded fintech startups that build financial resilience for Americans by improving income generation and expense management, risk mitigation and recovery, and asset and wealth building. Washington | $500K – $2M | 14 | Leads | Active | — | Open |
| 21 | ▶ Kindred Ventures Kindred backs visionary and relentless founders building the future using technology and science at the earliest stages, often helping form companies before they exist. With Kindred Ventures IV and Kindred Selector II, the firm is emphasizing the novel intelligence frontier: AGI-capable models and harnesses that extend human capabilities, new AI-native consumer and enterprise experiences, physical AI, compute, infrastructure, energy, science, outer space, and inner space. San Francisco | $500K – $5M | 54 | Leads | Active | ~2 wks | Req'd |
| 22 | ▶ Anthemis Group Architect a more equitable, sustainable and human-centered digital economy where technology and innovation work together in service of a better society. We deploy financial, human and intellectual capital in service of a better system, backing early-stage founders at intersections of industry, technology and society. London | $1M – $10M | 19 | Leads | Active | ~1 mo | Req'd |
| 23 | ▶ Inertia Ventures Inertia invests in AI-native companies built to become core infrastructure for legacy industries, especially platforms operating in regulated, context-heavy, and physical-world workflows where durable data, compliance, audit trails, or embodied operations create compounding advantages. New York | $2M – $15M | 66 | Leads | Active | ~2 wks | Req'd |
| 24 | ▶ Impact America Fund Tech-enabled businesses built for and by people in marginalized communities create new frameworks of ownership and opportunity. Traditional VCs miss billion-dollar markets in overlooked communities. Oakland | $250K – $3M | 32 | Leads | Active | ~1 mo | Req'd |
| 25 | ▶ AIX Ventures AI-native companies where artificial intelligence is the core product and competitive moat, not just a feature. Three investment baskets: (1) AI infrastructure (vector databases, model serving, optimization), (2) vertical applications with 20%+ performance advantages, and (3) frontier research with clear commercialization paths. Palo Alto | $750K – $3M | 25 | Leads | Active | ~1 wk | Open |
| 26 | ▶ White Star Capital Technology companies are becoming intertwined with the global economy more so than ever before. The most compelling founders build businesses through a broader world view. White Star Capital backs globally ambitious entrepreneurs at Series A, B, and Seed stages across North America, Europe, and Asia, helping them scale internationally through deep local presence on three continents. London | $1M – $25M | 41 | Leads | Active | ~1 mo | Open |
| 27 | ▶ Cake Ventures We invest in founders with global ambitions creating products that meet tomorrow's internet users' needs through demographic change. Focus on aging & longevity, spending power of women, and the new majority (majority-minority shift). San Francisco | $200K – $750K | 20 | Both | Active | ~2 wks | Open |
| 28 | ▶ Debut Capital Early-stage venture capital for IT and Biotech companies in Colorado Front Range and Mid-Atlantic. Focus on experienced founding teams solving important problems with potential for significant financial returns. Patient capital approach with operational support and deep regional networks. New York | $500K – $5M | 48 | Leads | Active | ~2 wks | Req'd |
| 29 | ▶ Expansion Venture Capital Entrepreneurs, not VCs, build great companies. We invest early in great & passionate entrepreneurs and serve as long-term partners. Available 24/7 to help founders with mentorship, product-market fit, fundraising, business development, customer acquisition, talent sourcing, and strategic partnerships. New York | $250K – $1M | 30 | Leads | Active | ~1 wk | Open |
| 30 | ▶ Expa We build category-defining companies through a combination of design, product, operations, and capital. We identify market gaps, pair brilliant founders with Expa's studio resources, and help them build companies that reshape entire industries. San Francisco | $500K – $5M | 60 | Leads | Active | ~1 wk | Open |
| 31 | ▶ Euclid Ventures Vertical AI will create hundreds of billions of enterprise value over the next decade. We back domain-expert founders building purpose-built AI solutions for specific industries from Day Zero — pre-product, pre-traction, pre-everything. San Francisco | $500K – $2M | 18 | Leads | Active | — | Open |
| 32 | ▶ TenOneTen Ventures Technical founders backing technical founders. We invest early in technical teams transforming major industries facing existential threats and tremendous opportunities. We target essential sectors—healthcare, logistics, real estate, manufacturing—where technical innovation solves critical problems. Los Angeles | $250K – $5M | 24 | Leads | Active | ~2 wks | Open |
| 33 | ▶ Daring Ventures Extraordinary talent is equally distributed. Extraordinary opportunity is not. We invest in non-obvious founders building critical infrastructure for overlooked markets—solving operational friction in complex industries with real relationships, judgment, and expertise. | $250K – $1M | 4 | Follows | Active | ~1 wk | Req'd |
| 34 | ▶ Kaedan Capital Entrepreneur-centric private investment firm backing Israeli-related seed to early-stage ventures across diverse technology areas. Patient partners who allow founders to build global tech companies at their own pace. Tel Aviv | $250K – $1.5M | 21 | — | Active | ~1 mo | Open |
| 35 | ▶ Cathay Innovation Startups positioned as transformation partners with Fortune 500 corporates create the most impactful solutions. We believe the next generation of market leaders will emerge through collaborative innovation between startups and incumbent enterprises, supported by global expertise and capital. Paris | $5M – $100M | 16 | Both | Active | ~1 mo | Req'd |
| 36 | ▶ Gigafund Back the world's most ambitious and transformative entrepreneurs capable of building world-defining companies over 20+ years. Invest in founders with independent thought and first-principles vision to solve humanity's biggest problems across all sectors and geographies. Austin | $1M – $500M | 18 | Leads | Active | 3+ mo | Open |
| 37 | ▶ TheoryForge Operator-led fund investing in ambitious founders building transformative AI applications. We partner with technical founders who understand AI/ML deeply and are solving real customer problems with capital efficiency. Great product is always the best marketing. | $200K – $500K | 38 | Both | Active | ~2 wks | Req'd |
| 38 | ▶ Made by Bread Great companies are built through boring magic — systematic, unglamorous work combining exceptional product design with operational excellence. We pair capital with hands-on product/design expertise and team-building support to help founders execute at venture scale. | $300K – $3M | 4 | Leads | Active | ~2 wks | Open |
Investors on this page also frequently invest in these sectors
What other stages do these firms also invest in?
What other sectors do these firms also invest in?
Firms that frequently co-invest with investors on this page
F4 Fund tracks 38 VC firms that actively invest in insurance + healthcare & digital health at the Seed stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for seed insurance + healthcare & digital health investors is $2.6M – $2.6M, with a full range from $50K – $500M. The distribution breaks down as: 3 firms in the <$500K range, 7 firms in the $500K-$1M range, 6 firms in the $1M-$2M range, 11 firms in the $2M-$5M range, 5 firms in the $5M-$10M range, 6 firms in the $10M+ range.
Among the 38 firms tracked, 84% lead or co-lead rounds, and 8% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best seed insurance + healthcare & digital health investors combine domain expertise with an active portfolio in the space. Among these firms, 33% prefer warm introductions, and the average firm has 40 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.