7 VC firms investing in travel & hospitality and biotech & life sciences at the Seed stage.
F4 Fund tracks 7 VC firms that actively invest in travel & hospitality + biotech & life sciences at the Seed stage, with check sizes ranging from $50K – $50M (median: $2.8M – $2.8M). As of August 2026, and 57% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,699+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Montage Ventures Montage Ventures aims to support radical thinkers who are bringing new ideas and platforms to foster change within the financial services, commerce and health sectors, leveraging AI as a key transformative agent. | $250K – $1M | 51 | N/A | 2mo | N/A | N/A |
| 2 | ▶ New Enterprise Associates (NEA) NEA partners with ambitious founders at every stage of company building, from pre-seed through IPO. They invest at the intersection of technology and healthcare, believing the most transformational innovation occurs where deep domain expertise meets world-class technical founders. NEA serves as both capital provider and active operator. Menlo Park | $1M – $50M | 26 | Both | Active | ~2 mo | Open |
| 3 | ▶ DeVC Back relentlessly resourceful founders with capital, wisdom, and networks from a collective of 50+ operators who have built and scaled companies like CRED, Haptik, Park+, OfBusiness, Razorpay, and Swiggy, favoring ground-reality operating experience over trend-chasing. Bengaluru, India | $50K – $500K | 26 | Follows | Active | N/A | N/A |
| 4 | ▶ Expa We build category-defining companies through a combination of design, product, operations, and capital. We identify market gaps, pair brilliant founders with Expa's studio resources, and help them build companies that reshape entire industries. San Francisco | $500K – $5M | 60 | Leads | Active | ~1 wk | Open |
| 5 | ▶ SEGO Venture Channel capital from a large base of retail and institutional investors into vetted, growth-stage Spanish companies with strong public narratives, giving individual investors direct equity access normally reserved for institutional VC. Madrid | $300K – $10M | 11 | N/A | Active | N/A | N/A |
| 6 | ▶ Construct Capital Foundational industries (manufacturing, logistics, defense, energy) have been neglected for decades. Tech founders can unlock trillions in value by applying software, AI, automation, and cloud infrastructure to transform these sectors. This is the largest venture opportunity: tripling the Industrials market cap from $3.7T to $55T by 2050. Washington | $2M – $6M | 27 | Leads | Active | ~1 mo | Open |
| 7 | ▶ TheoryForge Operator-led fund investing in ambitious founders building transformative AI applications. We partner with technical founders who understand AI/ML deeply and are solving real customer problems with capital efficiency. Great product is always the best marketing. | $200K – $500K | 38 | Both | Active | ~2 wks | Req'd |
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Firms that frequently co-invest with investors on this page
F4 Fund tracks 7 VC firms that actively invest in travel & hospitality + biotech & life sciences at the Seed stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for seed travel & hospitality + biotech & life sciences investors is $2.8M – $2.8M, with a full range from $50K – $50M. The distribution breaks down as: 2 firms in the <$500K range, 1 firms in the $500K-$1M range, 2 firms in the $2M-$5M range, 1 firms in the $5M-$10M range, 1 firms in the $10M+ range.
Among the 7 firms tracked, 57% lead or co-lead rounds, and 14% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best seed travel & hospitality + biotech & life sciences investors combine domain expertise with an active portfolio in the space. Among these firms, 25% prefer warm introductions, and the average firm has 34 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.