12 VC firms investing in agetech & longevity at the Pre-Seed stage.
Ranked by sector depth: the share of each firm's classified portfolio in this sector, its absolute count of investments here, and how recently it last invested. Firms need at least three portfolio companies in the sector to appear.
F4 Fund tracks 12 VC firms that actively invest in agetech & longevity at the Pre-Seed stage, with check sizes ranging from $100K – $40M (median: $1.1M). As of September 2026, 75% of these firms lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 2,037+ researched VC firms. Ranked by how much of each firm's portfolio is actually in this sector, and how recently it invested.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Pacific Channel Investing in great people using breakthrough science and advanced engineering to create transformative impact across the future of food, health, and the environment. Long-term, active partner providing capital, expertise, and networks rather than passive investment. Auckland | $500K – $13M | 49 | Leads | Active | N/A | Open |
| 2 | ▶ Verdex Capital Dedicated to advancing Canadian agriculture, Verdex invests in the entrepreneurs, technologies, and businesses shaping the future of food and agriculture, providing patient capital suited to agriculture's seasonal cycles and long validation timelines. Calgary, AB, Canada | $500K – $1M | 16 | Follows | Active | N/A | Open |
| 3 | ▶ Galvanize Climate Solutions Galvanize invests at the intersection of energy innovation, resilience, and intelligence, backing the 'New Economy' companies essential to electrification, rising power demand, industrial modernization, and digitization -- from pre-seed food/agriculture/ocean/forestry ventures (Ponderosa) through growth-stage energy transition and AI-infrastructure companies (Venture & Growth). San Francisco | $1M – $40M | 70 | N/A | Active | N/A | Req'd |
| 4 | ▶ Tenacious Ventures Australia's first and only specialist agrifood tech VC, backing early-stage founders solving practical problems for Australian and comparable farming conditions to accelerate a resilient, regenerative agri-food future. Manly, Australia | $200K – $1M | 13 | Both | Active | N/A | Req'd |
| 5 | ▶ Jazz Venture Partners Breakthroughs at the convergence of technology, science, and humanity improve how we live, work, and experience the world. We invest in transformative technologies for human performance and wellbeing. San Francisco | $100K – $5M | 51 | Both | Active | ~2 wks | Req'd |
| 6 | ▶ Primetime Partners The longevity economy is a massive addressable market. Companies transforming quality of life for aging adults will be highly profitable and impactful. Experienced founders over 50 solve aging problems better because they understand them firsthand. New York | $250K – $1M | 36 | Leads | Active | ~1 mo | Open |
| 7 | ▶ Town Hall Ventures #41 · Emerging 100 · 2026 Using innovation to fix health inequities: partnering with founders building technology and service solutions that expand access to high-quality healthcare for underserved populations (Medicaid/dual-eligible seniors, rural communities, school-age youth) across primary care, mental health, kidney care, palliative care, and maternity health. New York | $3M – $30M | 41 | Both | Active | N/A | N/A |
| 8 | ▶ Heartfelt Capital Europe's first cheque fund: the first institutional investor for exceptional European (and European-origin) founders, helping them go from 0 to 1 and reach product-market fit, backed by anchor corporate relationships with Axel Springer and Porsche. Berlin | $100K – $400K | 161 | Both | Active | N/A | Open |
| 9 | ▶ Astanor The agrifood value chain has reached a tipping point where incremental change is not enough; systemic disruption and regeneration of the food and agriculture system is required to restore human, planetary, and economic health. Brussels, Belgium | $1M – $25M | 52 | Leads | Active | N/A | N/A |
| 10 | ▶ Tip Top VC The future of AI is vertical. We back founders reinventing large, often overlooked industries end-to-end with AI-native, embedded software rather than generic horizontal tools. Austin | $100K – $500K | 16 | Follows | Active | N/A | Open |
| 11 | ▶ TitletownTech Invest in early-stage, scalable ventures with exceptional founders building emerging technology across Digital Health, Manufacturing, Supply Chain, Agriculture, and Energy, digitally transforming industries core to the strengths of our Green Bay Packers and Microsoft partners and the Midwest region. Green Bay, WI | $200K – $2M | 39 | Both | Active | N/A | Open |
| 12 | ▶ Next Age The Silver Economy is a large, fast-growing, and underfunded market. Next Age accelerates pre-seed/seed startups building products for older adults across health, finance, leisure, aging-in-place, aging-at-work, and age-friendly-city use cases, staging investment from an initial convertible through follow-on capital from SOSV and CDP Venture Capital. Ancona, Italy | $120K – $1.5M | 22 | Leads | Active | ~2 mo | Open |
What other stages do these firms also invest in?
What other sectors do these firms also invest in?
F4 Fund tracks 12 VC firms that actively invest in agetech & longevity at the Pre-Seed stage. Ranked by sector depth: the share of each firm's classified portfolio in this sector, its absolute count of investments here, and how recently it last invested. Firms need at least three portfolio companies in the sector to appear.
Based on F4's analysis, the median check size for pre-seed agetech & longevity investors is $1.1M, with a full range from $100K – $40M. The distribution breaks down as: 2 firms in the <$500K range, 4 firms in the $500K-$1M range, 1 firms in the $1M-$2M range, 1 firms in the $2M-$5M range, 1 firms in the $5M-$10M range, 3 firms in the $10M+ range.
Among the 12 firms tracked, 75% lead or co-lead rounds, and 17% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best pre-seed agetech & longevity investors combine domain expertise with an active portfolio in the space. Among these firms, 30% prefer warm introductions, and the average firm has 47 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.
Investors on this page also frequently invest in these sectors