F4 Champions · Season 1
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F4 Champions · Season 1
You're researching investors. We want to see what you're building.
Join the open accelerator where your standing changes with what you ship. Enrollment closes August 2.
18 VC firms investing in biotech & life sciences and climate & clean energy at the Growth stage.
F4 Fund tracks 18 VC firms that actively invest in biotech & life sciences + climate & clean energy at the Growth stage, with check sizes ranging from $100K – $5000M (median: $20.9M – $20.9M). As of July 2026, and 83% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,544+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ RA Capital Management Evidence-based, multi-stage investing in healthcare, life sciences, and planetary health. RA Capital pairs deep scientific diligence (via proprietary TechAtlas platform) with flexible multi-stage capital—from NewCo incubation through public markets—to support breakthrough companies from inception through commercialization. The firm's core belief is that rigorous landscape research and scientific depth consistently identify winners before the market recognizes them. Boston | $500K – $200M | 38 | Both | Active | ~1 mo | Open |
| 2 | ▶ Initialized Capital Passion and vision matter more than pedigree. We seek founders with grit, audacity, and a spark of rebellion—regardless of background. We invest early, before success is inevitable, and support founders from 0-to-1 through Series A. San Francisco | $250K – $2M | 185 | Leads | Active | ~2 wks | Open |
| 3 | ▶ Giant Ventures The biggest companies of the century will be built solving the world's most pressing problems. We champion ambitious founders using technology to reshape civilization around climate, health, and inclusive capitalism. London | $500K – $15M | 35 | Both | Active | ~2 mo | Open |
| 4 | ▶ B Capital Group Back extraordinary entrepreneurs throughout the company-building lifecycle from seed to IPO. Combine venture capital expertise with BCG management consulting to accelerate value creation. Support founders with capital, strategic guidance, and access to global networks. San Francisco | $250K – $50M | 34 | Leads | Active | ~2 wks | Req'd |
| 5 | ▶ Tesi Tesi (Finnish Industry Investment Ltd) is a state-owned investment company that helps Finland's most promising companies grow bigger. Tesi invests on market terms as a minority co-investor alongside private capital in Finnish startups, scale-ups, and industrial projects, as well as in VC and PE funds. Its mandate is both financial returns and economic impact — driving growth, jobs, and renewal in the Finnish economy. Helsinki | $1M – $30M | 31 | Follows | Active | 3+ mo | Open |
| 6 | ▶ Seventure Partners Seventure Partners identifies and backs innovative European companies in Life Sciences and Digital Technologies at all stages from seed to pre-IPO, serving as the lead investor and active board-level partner. The firm is a global pioneer in microbiome investing and has built a 25+ year track record of 150+ exits and 30 IPOs. Institutional backing from Natixis Investment Managers/Groupe BPCE provides unique co-investment and network access. Paris | $500K – $10M | 41 | Leads | Active | ~2 mo | Open |
| 7 | ▶ General Atlantic The dedicated partner for entrepreneurs and investors building long-term value: patient growth capital plus deep sector expertise and a global operating platform for category-leading, capital-efficient businesses at an inflection point. New York | $50M – $500M | 28 | Leads | Active | N/A | N/A |
| 8 | ▶ Lerer Hippeau As founder-operators, we see returns in relationships. We back ambitious founders with exceptional vision at the earliest stages with capital, mentorship, and network access. | $100K – $1M | 73 | Leads | Active | ~1 mo | Open |
| 9 | ▶ BGF BGF provides patient, minority growth capital to ambitious SMEs and deep tech/life sciences startups across the UK and Ireland. Founded to address the SME funding gap, BGF never takes controlling stakes, provides long-term support without fixed exit deadlines, and offers portfolio access to its talent network, operating specialists, and community platform. London | $3.8M – $38M | 22 | Both | Active | ~2 mo | Open |
| 10 | ▶ Alumni Ventures We democratize venture capital by providing individual accredited investors with professional-grade access to elite venture opportunities. We leverage our massive 850,000+ community network and 11,000+ investors to create unique value for founders, sourcing and diligencing deals alongside top-tier VCs (a16z, Sequoia, Khosla) without leading rounds. Our network is our competitive advantage—it compounds value for all stakeholders. Manchester, NH | $250K – $5M | 58 | Follows | Active | ~2 wks | Open |
| 11 | ▶ Mubadala Mubadala partners with world-class companies and institutions to drive transformational growth across strategic sectors and geographies. We believe in long-term value creation through patient capital, operational expertise, and global partnerships aligned with Abu Dhabi's economic diversification. Abu Dhabi | $5M – $5000M | 46 | Both | Active | ~2 mo | Req'd |
| 12 | ▶ SpeedInvest Backs globally ambitious technology companies from pre-seed and seed through selected growth rounds using specialist EMEA sector teams and a platform model for capital, customers, talent, follow-on investors, and operational support. Vienna | $250K – $30M | 49 | Leads | Active | N/A | Open |
| 13 | ▶ Redalpine Redalpine backs companies at the convergence of software and science — where rigorous engineering meets scientific breakthroughs. Half the team are scientists, half are operators, enabling them to engage deeply with highly technical founders and support them hands-on from day one through to exit. Primary focus areas: frontier science and biotech, digital health, AI and automation, fintech, synthetic biology, and climate tech. Zug | $500K – $5M | 40 | Leads | Active | N/A | N/A |
| 14 | ▶ Emerson Collective Emerson Collective invests in entrepreneurs and innovators driven by purpose, seeking consequential companies that deliver both generational impact and venture-scale returns. The firm targets sectors where biggest market opportunities meet meaningful impact levers: energy & environment, digital health, fintech, education, work, and media. Palo Alto | $10M – $700M | 16 | Both | Active | ~1 mo | Req'd |
| 15 | ▶ IDG Capital Backing founders and teams building lasting companies across TMT, healthcare, consumer & entertainment, and advanced manufacturing/clean tech, with a multi-decade time horizon and a bridge role between China and global capital markets. Hong Kong | $1M – $100M | 23 | Both | Active | ~2 mo | Req'd |
| 16 | ▶ Gaingels Equity of access and representation in venture capital delivers positive returns. Diverse and underrepresented (including LGBTQ+) leaders of high-growth companies deserve capital access. When these founders succeed, they influence ecosystems and open doors for historically excluded groups. New York | $200K – $500K | 29 | Follows | Active | ~2 wks | Open |
| 17 | ▶ Cathay Innovation Startups positioned as transformation partners with Fortune 500 corporates create the most impactful solutions. We believe the next generation of market leaders will emerge through collaborative innovation between startups and incumbent enterprises, supported by global expertise and capital. Paris | $5M – $100M | 16 | Both | Active | ~1 mo | Req'd |
| 18 | ▶ British Business Bank As the UK's state-owned economic development bank, British Business Bank exists to improve smaller and scaling businesses' access to finance and to support the transition to net zero, deploying public capital as a fund-of-funds, co-investor, and direct equity investor to fill gaps the private market leaves unfilled. Sheffield, UK | $12.5M – $50M | 7 | Both | Active | N/A | N/A |
Investors on this page also frequently invest in these sectors
What other stages do these firms also invest in?
What other sectors do these firms also invest in?
F4 Fund tracks 18 VC firms that actively invest in biotech & life sciences + climate & clean energy at the Growth stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for growth biotech & life sciences + climate & clean energy investors is $20.9M – $20.9M, with a full range from $100K – $5000M. The distribution breaks down as: 1 firms in the <$500K range, 1 firms in the $500K-$1M range, 1 firms in the $1M-$2M range, 2 firms in the $2M-$5M range, 2 firms in the $5M-$10M range, 11 firms in the $10M+ range.
Among the 18 firms tracked, 83% lead or co-lead rounds, and 17% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best growth biotech & life sciences + climate & clean energy investors combine domain expertise with an active portfolio in the space. Among these firms, 33% prefer warm introductions, and the average firm has 43 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.