41 VC firms investing in enterprise software and manufacturing & industrial at the Series A stage.
F4 Fund tracks 41 VC firms that actively invest in enterprise software + manufacturing & industrial at the Series A stage, with check sizes ranging from $10K – $500M (median: $2.8M – $2.8M). As of June 2026, and 93% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,358+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ The Council Fund We invest in proven operators reshaping essential industries. Our focus is on operator-founders who have deep scaling experience at companies like Uber, Flexport, and Northrop Grumman. We back First Builders—specialists and generalists who understand how to build and scale organizations. San Francisco | $500K – $5M | 28 | Leads | Active | ~2 wks | Open |
| 2 | ▶ Initialized Capital Passion and vision matter more than pedigree. We seek founders with grit, audacity, and a spark of rebellion—regardless of background. We invest early, before success is inevitable, and support founders from 0-to-1 through Series A. San Francisco | $250K – $2M | 185 | Leads | Active | ~2 wks | Open |
| 3 | ▶ Alpaca VC We invest in technology companies that reshape foundational industries – real estate, commerce, manufacturing, energy, logistics, and agriculture. Founded by entrepreneurs for entrepreneurs, we bring operational guidance, strategic insights from proprietary Field Studies research, and downstream capital access. We believe the startup journey is better together, providing hands-on support to exceptional founders building enduring companies. New York | $500K – $5M | 72 | Both | Active | ~2 wks | Open |
| 4 | ▶ Link Ventures We invest in early-stage AI-driven startups founded by top technical talent from MIT, Harvard, and Boston ecosystem. We believe transformative AI innovation is emerging from university-affiliated founders backed by comprehensive operational support, mentorship, and access to world-class networks. Cambridge | $1M – $8M | 76 | Leads | Active | ~2 wks | Req'd |
| 5 | ▶ Lorimer Ventures Builders first. We back experienced operators who understand business fundamentals and the pain points of scaling software companies. We invest at inception stage with 100+ operator LPs providing talent, customers, and capital beyond the check. Brooklyn | $50K – $300K | 59 | Both | Active | ~1 wk | Req'd |
| 6 | ▶ Building Ventures The physical world is programmable hardware. We invest in entrepreneurs transforming the built environment across design, build, operate, and experience. Deep AEC domain expertise combined with technical innovation creates structural value. We partner with visionary founders using our network of 100+ AEC executives for pilots, feedback, and distribution. Boston | $100K – $10M | 42 | Leads | Active | 3+ mo | Req'd |
| 7 | ▶ Root Ventures Root Ventures is composed entirely of practicing engineers and hardware hackers who explicitly underwrite 'engineering risk' in technically challenging areas like robotics, developer tools, and manufacturing tech that many generalist funds avoid. They provide capital, operational support, and serve as an 'invisible employee' to technical founding teams. San Francisco | $1M – $3M | 40 | Leads | Active | ~1 mo | Open |
| 8 | ▶ Energy Foundry Earth Foundry backs founders transforming critical industries, including energy, mobility, waste, water, agriculture, and infrastructure, using hardware, software, services, and material science innovations. Chicago | $1M – $5M | 23 | Leads | Active | ~2 mo | Req'd |
| 9 | ▶ Forward Deployed VC Backs mission-critical technology companies in Defense, Energy, Industrials, and AI — specifically applied AI solving tangible physical problems. Invests from a network of 150+ operators from Palantir, Anduril, and SpaceX. San Francisco | $100K – $5M | 23 | Follows | Active | ~1 mo | Req'd |
| 10 | ▶ Ardent Venture Partners Software will transform as AI-native applications unlock value in unstructured data (emails, contracts) that traditional software has sidelined. We back founders building the next generation of vertical operating systems, AI-native applications, and embedded finance solutions. Washington | $250K – $3M | 21 | Both | Active | ~2 mo | Req'd |
| 11 | ▶ Alpha Edison Identify and partner with visionary entrepreneurs building category-creating companies that unlock entirely new addressable markets. Focus on 'silent suffering' where customers tolerate suboptimal solutions. Use AI, data, and behavioral science to identify non-obvious market opportunities and founder-market fit. Los Angeles | $250K – $10M | 55 | Both | Active | ~2 wks | Open |
| 12 | ▶ Glasswing Ventures Early-stage founders using AI and frontier technology to reinvent enterprise and security markets. We seek technical founders who deeply understand their problem domain, have operating experience at scale, and are committed to responsible AI development. We provide not just capital but hands-on operational support through our Building Partners model. Boston | $250K – $15M | 41 | Leads | Active | ~2 wks | Open |
| 13 | ▶ True Ventures We invest in brilliant people who bring ideas that matter to life. We focus on AI-native founders building companies with strong founder-product fit, aligned on mission and meaning, seeking creative freedom and psychological safety. Great companies are built by diverse teams supported and empowered to be maximally creative. Palo Alto | $500K – $3M | 41 | Leads | Active | ~1 wk | Req'd |
| 14 | ▶ Launch NY Upstate New York can be the region for high-growth startup success. We provide mentorship, capital, and connections to fuel innovation, job creation, and regional economic growth. Founders aligned with community impact, job creation, and solving regional challenges are ideal. Buffalo, New York | $200K – $1M | 28 | Both | Active | ~1 mo | Req'd |
| 15 | ▶ VSC Ventures VSC Ventures backs founders using AI to fix data, labor, and safety challenges in Dirty, Dusty, Dangerous industries. They combine capital with integrated PR/media infrastructure to help portfolio companies build narrative and distribution as a competitive moat. San Francisco | $250K – $750K | 17 | Follows | Active | ~1 mo | Req'd |
| 16 | ▶ Contrary Identify and invest in the world's top talent before they start a company. Build lifelong relationships through a proprietary university scout network at Stanford, MIT, Harvard, and other elite universities. Back exceptional founders within 1-3 years of graduation before they are widely recognized. San Francisco | $100K – $15M | 55 | Both | Active | ~2 wks | Req'd |
| 17 | ▶ Origin Ventures Origin Ventures invests in bold founders leading humanity into the fifth economic era—the Artificial Intelligence Economy. AI is fundamentally transforming how we live, work, and play through infrastructure, software, applications, and services that drive productivity and enable autonomous systems. The firm is an early believer in extraordinary people with deep domain expertise who challenge norms and redefine economies. Chicago | $1M – $8M | 55 | Leads | Active | ~1 mo | Open |
| 18 | ▶ Myriad Venture Partners Back exceptional founders building transformational B2B companies in AI, enterprise software, cybersecurity, and clean technology. The Myriad Model combines capital with a curated ecosystem of 30+ Fortune 500 executives who accelerate commercial traction through introductions, POCs, and commercial contracts. Boston | $250K – $3M | 23 | Leads | Active | — | — |
| 19 | ▶ Growth Warrior Capital Dangerous founders building AI and automation for enterprise and industrial markets. The 4D Economy—where AI solves real operational challenges in manufacturing, workforce management, and public safety. We back founders with operator mentality and deep domain expertise, providing capital plus operational frameworks that help companies grow 200% faster. Austin | $1M – $5M | 8 | Both | Active | ~2 mo | Req'd |
| 20 | ▶ Mercury Fund Mercury backs disruptive AI and Blockchain-enabled startups outside Silicon Valley, with a focus on capital-efficient founders in the Central US reimagining core industries including fintech, enterprise software, healthcare, energy, manufacturing, and logistics through their five investment themes: Work, Build, Journeys, Data, and Power. Houston | $100K – $5M | 51 | Leads | Active | ~2 mo | Open |
| 21 | ▶ 8VC Partner with elite founders building transformational technologies that create lasting economic and societal value. Focus on Smart Enterprise across five sectors: Logistics, Life Sciences, Healthcare, IT Infrastructure, and Government/Defense. Invest in platforms that enable human experts to solve non-linear problems through data integration and network effects. Austin | $500K – $50M | 30 | Leads | Active | ~2 wks | Open |
| 22 | ▶ REMUS Capital Building, not betting, with rebels transforming massive traditional industries through applied AI. Hands-on operational partnership combining capital with customer acquisition, team building, and strategic guidance. Boston | $1M – $20M | 27 | Leads | Active | ~2 wks | Req'd |
| 23 | ▶ XYZ Venture Capital Great companies aren't born, they're made. XYZ invests in early-stage founders with exceptional execution capability, deep domain expertise, or lived experience insights. They specialize in helping founders navigate the earliest stages by providing capital plus strategic operational support. San Francisco | $10K – $5M | 27 | Leads | Active | ~2 wks | Req'd |
| 24 | ▶ Impact America Fund Tech-enabled businesses built for and by people in marginalized communities create new frameworks of ownership and opportunity. Traditional VCs miss billion-dollar markets in overlooked communities. Oakland | $250K – $3M | 32 | Leads | Active | ~1 mo | Req'd |
| 25 | ▶ Crosscut Ventures Partner with visionary founders building category-defining frontier technologies that address humanity's most pressing problems. We invest in deep tech, hardware, and climate solutions emerging from technical communities like SpaceX, focusing on founders with big ambitions, not incremental ideas. Los Angeles | $500K – $10M | 24 | Leads | Active | ~1 mo | Req'd |
| 26 | ▶ Wischoff Ventures Bringing physical-world operations online through 'the new supply chain.' Wischoff backs founders digitizing logistics, fintech infrastructure, manufacturing, and construction. Portfolio chemistry—companies becoming customers of each other. Solo GP with hands-on operational guidance, founder amplification, and regulated-market expertise. New York | $800K – $1.6M | 16 | Leads | Active | ~1 wk | Open |
| 27 | ▶ Foundry Group We invest in startups and venture funds, creating a symbiotic network that propels innovation. Our approach is characterized by long-term thinking and a 'give first' philosophy. Boulder, Colorado | $500K – $10M | 26 | Leads | Active | ~1 mo | Req'd |
| 28 | ▶ Khosla Ventures Technology-based economic disruption of large markets through black swan investments. We seek founders with domain expertise and unreasonable conviction to build billion-dollar companies solving the world's largest problems. Menlo Park | $500K – $50M | 38 | Both | Active | ~2 wks | Open |
| 29 | ▶ Battery Ventures Battery Ventures operates as a stage-agnostic firm backing technology-driven category leaders across all growth stages from seed to buyout. The firm believes the best tech investments span the entire founder journey, and they practice collaborative, research-focused investing with embedded operational support through their Portfolio Services platform. They seek technical founders with deep domain expertise and experienced operators building in four core sectors: Application Software, Infrastructure Software, Consumer, and Industrial Tech + Life Science Tools. Boston | $1M – $500M | 23 | Both | Active | ~2 wks | Open |
| 30 | ▶ Outsiders Fund Technological innovation is unevenly distributed. The hottest, most visible sectors attract talent and capital, while overlooked industries hide massive value creation opportunities. We back unconventional founders disrupting unglamorous, technology-inefficient, long-standing industries. New York | $500K – $8M | 34 | Both | Active | ~2 wks | Open |
| 31 | ▶ ff Venture Capital ffVC invests in driven problem-solvers building high-potential companies in emerging industries: AI, Manufacturing, Energy, Robotics, and Security. We provide capital alongside deep operational expertise, board participation, and access to a 35,000+ founder and investor ecosystem. We bet on founders with industry expertise, clear paths to $100M+ revenue, and defensible competitive advantages. New York | $300K – $700K | 22 | Leads | Active | ~2 mo | Req'd |
| 32 | ▶ Day One Ventures We help mission-driven pioneers win by harnessing the power of storytelling, art and culture. We back early-stage companies with customer obsession in their DNA and accelerate the mass adoption of technologies they create. Founders need more than capital—they need strategic support in building their narrative and leveraging media to accelerate adoption. San Francisco | $300K – $5M | 27 | Leads | Active | ~1 wk | Open |
| 33 | ▶ Argonautic Ventures AI is a milestone in data maturity progression, not a product category. Argonautic invests in founders building data-centric solutions across infrastructure (horizontal) and vertical markets. Multi-fund structure allows pre-seed to Series B deployment with unified thesis: recognizing verticals at different data adoption stages and deploying capital to those crossing inflection points into AI operationalization. | $250K – $1M | 7 | Both | Active | ~2 wks | Open |
| 34 | ▶ Skyview Capital Unlock value from overlooked corporate assets through operational excellence and strategic management. Partner with outstanding management teams to transform divisions into standalone, high-growth companies. Los Angeles | $100K – $75M | 11 | Leads | Active | ~1 wk | Open |
| 35 | ▶ Transpose Platform First-check investors to exceptional founders building category-defining companies and to emerging venture funds reshaping the industry. Formation-stage specialists operating as partners from inception, not simply deploying capital. Houston | $500K – $15M | 20 | Leads | Active | ~2 wks | Req'd |
| 36 | ▶ Fika Ventures Investing in subject matter experts shaping the future of their industries. We lead with our values and build trust through action. We believe the best founders have deep industry expertise and need tireless operational support, not just capital. We partner with founders for the long term, staying engaged 24/7. Los Angeles | $1M – $5M | 27 | Leads | Active | ~1 wk | Open |
| 37 | ▶ Pillar VC We invest in technical breakthroughs that overcome the world's greatest challenges. We partner at inception with technically brilliant dreamers who see past impossible to inevitable. We evaluate scientific opportunities through both commercial potential and human impact lenses. Boston | $100K – $10M | 22 | Leads | Active | ~2 mo | Open |
| 38 | ▶ Commonweal Ventures Entrepreneurs who work constructively with government to harness its unique strengths—scale, credibility, regulatory power, data, and funding—enjoy asymmetric advantages. 24% of venture-backed unicorns used government support. We partner with founders to unlock government as a growth lever. New York | $500K – $2M | 26 | Both | Active | ~1 mo | Req'd |
| 39 | ▶ Cathay Innovation Startups positioned as transformation partners with Fortune 500 corporates create the most impactful solutions. We believe the next generation of market leaders will emerge through collaborative innovation between startups and incumbent enterprises, supported by global expertise and capital. Paris | $5M – $100M | 16 | Both | Active | ~1 mo | Req'd |
| 40 | ▶ Sher Ventures Exceptional founders applying unique talents and backgrounds to produce disruptive and differentiated products and services. Minimum $500K ARR at entry. Generalist across AI, B2B SaaS, logistics, healthcare, and advanced manufacturing. Sugar Land, TX | $25K – $100K | 4 | Follows | Active | ~1 mo | Open |
| 41 | ▶ IGC - Innovative Growth Capital IGC pioneered the Reverse VC™ model — starting with corporate demand rather than capital deployment. Their ReverseVision platform identifies what Global 5000 companies want to buy, then matches emerging tech founders to those demand signals. Investment flow: Demand → Commercialization → Valuation → Capital → Exit. This approach claims higher success rates, better deal terms, and reduced downside risk by replacing intuition with engineered outcomes. San Francisco | $25K – $500K | 1 | Leads | Active | ~1 mo | Open |
Investors on this page also frequently invest in these sectors
What other stages do these firms also invest in?
What other sectors do these firms also invest in?
Firms that frequently co-invest with investors on this page
F4 Fund tracks 41 VC firms that actively invest in enterprise software + manufacturing & industrial at the Series A stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for series a enterprise software + manufacturing & industrial investors is $2.8M – $2.8M, with a full range from $10K – $500M. The distribution breaks down as: 3 firms in the <$500K range, 4 firms in the $500K-$1M range, 7 firms in the $1M-$2M range, 13 firms in the $2M-$5M range, 8 firms in the $5M-$10M range, 6 firms in the $10M+ range.
Among the 41 firms tracked, 93% lead or co-lead rounds, and 7% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best series a enterprise software + manufacturing & industrial investors combine domain expertise with an active portfolio in the space. Among these firms, 50% prefer warm introductions, and the average firm has 34 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.