16 VC firms investing in fintech & payments and biotech & life sciences at the Growth stage.
F4 Fund tracks 16 VC firms that actively invest in fintech & payments + biotech & life sciences at the Growth stage, with check sizes ranging from $100K – $5000M (median: $25.1M – $25.1M). As of June 2026, and 88% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,358+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Giant Ventures The biggest companies of the century will be built solving the world's most pressing problems. We champion ambitious founders using technology to reshape civilization around climate, health, and inclusive capitalism. London | $500K – $15M | 35 | Both | Active | ~2 mo | Open |
| 2 | ▶ Founders Fund Back revolutionary technologies and visionary founders who think in first principles. We invest across all stages when conviction exists, providing patient capital and board-level partnership to founders building consequential companies that reshape industries. San Francisco | $500K – $50M | 33 | Leads | Active | ~2 wks | Req'd |
| 3 | ▶ iGlobe Partners Unearth, invest and grow startups into global leaders. iGlobe targets game-changing innovations at the frontier of deep tech — semiconductors, AI, quantum computing, and biotech — with a global orientation and a Singapore hub. Founded by Soo Boon Koh, Singapore's first female VC, the firm brings 25+ years of cross-border investing expertise and a top-quartile performance record. Singapore | $1M – $15M | 49 | Both | Active | ~2 mo | Open |
| 4 | ▶ B Capital Group Back extraordinary entrepreneurs throughout the company-building lifecycle from seed to IPO. Combine venture capital expertise with BCG management consulting to accelerate value creation. Support founders with capital, strategic guidance, and access to global networks. San Francisco | $250K – $50M | 34 | Leads | Active | ~2 wks | Req'd |
| 5 | ▶ Upfront Ventures Early investors and long-term partners. We back exceptional founders solving real problems across sectors. When you hit a bump in the road, we're there solving problems alongside you with operational expertise and network leverage. | $1M – $15M | 46 | Leads | Active | ~2 wks | Req'd |
| 6 | ▶ Lerer Hippeau As founder-operators, we see returns in relationships. We back ambitious founders with exceptional vision at the earliest stages with capital, mentorship, and network access. | $100K – $1M | 73 | Leads | Active | ~1 mo | Open |
| 7 | ▶ GV (Google Ventures) GV backs innovative founders moving the world forward, operating on long time horizons and dealing in decades, not rounds. Since 2023, GV has accelerated its focus on AI-native companies across infrastructure, applications, healthcare, and developer tools — with approximately 80% of new European investments now in AI. San Francisco | $500K – $50M | 30 | Both | Active | ~1 mo | Open |
| 8 | ▶ Alumni Ventures We democratize venture capital by providing individual accredited investors with professional-grade access to elite venture opportunities. We leverage our massive 850,000+ community network and 11,000+ investors to create unique value for founders, sourcing and diligencing deals alongside top-tier VCs (a16z, Sequoia, Khosla) without leading rounds. Our network is our competitive advantage—it compounds value for all stakeholders. Manchester, NH | $250K – $5M | 58 | Follows | Active | ~2 wks | Open |
| 9 | ▶ K5 Global K5 Global backs category-defining companies from inception to IPO. The firm leverages exceptional networks across media, entertainment, politics, finance, and technology to provide strategic value beyond capital. We believe the best companies are built by founders who can access world-class talent, capital, and strategic relationships. Los Angeles | $1M – $3M | 34 | Leads | Active | ~1 mo | Open |
| 10 | ▶ SpeedInvest Backs globally ambitious technology companies from pre-seed and seed through selected growth rounds using specialist EMEA sector teams and a platform model for capital, customers, talent, follow-on investors, and operational support. Vienna | $250K – $30M | 49 | Leads | Active | — | Open |
| 11 | ▶ Mubadala Mubadala partners with world-class companies and institutions to drive transformational growth across strategic sectors and geographies. We believe in long-term value creation through patient capital, operational expertise, and global partnerships aligned with Abu Dhabi's economic diversification. Abu Dhabi | $5M – $5000M | 41 | Both | Active | ~2 mo | Req'd |
| 12 | ▶ Andreessen Horowitz Backing the builders of the next layer of computing across AI infrastructure, defense, biotech, and American dynamism. Former 'Software is Eating the World' thesis evolved to 'AI is Eating Software'. Partners with technical founders building foundation models, cloud systems, and infrastructure for the AI era. Menlo Park | $1M – $200M | 48 | Both | Active | ~2 wks | Open |
| 13 | ▶ Battery Ventures Battery Ventures operates as a stage-agnostic firm backing technology-driven category leaders across all growth stages from seed to buyout. The firm believes the best tech investments span the entire founder journey, and they practice collaborative, research-focused investing with embedded operational support through their Portfolio Services platform. They seek technical founders with deep domain expertise and experienced operators building in four core sectors: Application Software, Infrastructure Software, Consumer, and Industrial Tech + Life Science Tools. Boston | $1M – $500M | 23 | Both | Active | ~2 wks | Open |
| 14 | ▶ Emerson Collective Emerson Collective invests in entrepreneurs and innovators driven by purpose, seeking consequential companies that deliver both generational impact and venture-scale returns. The firm targets sectors where biggest market opportunities meet meaningful impact levers: energy & environment, digital health, fintech, education, work, and media. Palo Alto | $10M – $700M | 16 | Both | Active | ~1 mo | Req'd |
| 15 | ▶ Gaingels Equity of access and representation in venture capital delivers positive returns. Diverse and underrepresented (including LGBTQ+) leaders of high-growth companies deserve capital access. When these founders succeed, they influence ecosystems and open doors for historically excluded groups. New York | $200K – $500K | 29 | Follows | Active | ~2 wks | Open |
| 16 | ▶ Cathay Innovation Startups positioned as transformation partners with Fortune 500 corporates create the most impactful solutions. We believe the next generation of market leaders will emerge through collaborative innovation between startups and incumbent enterprises, supported by global expertise and capital. Paris | $5M – $100M | 16 | Both | Active | ~1 mo | Req'd |
Investors on this page also frequently invest in these sectors
What other stages do these firms also invest in?
What other sectors do these firms also invest in?
F4 Fund tracks 16 VC firms that actively invest in fintech & payments + biotech & life sciences at the Growth stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for growth fintech & payments + biotech & life sciences investors is $25.1M – $25.1M, with a full range from $100K – $5000M. The distribution breaks down as: 1 firms in the <$500K range, 1 firms in the $500K-$1M range, 2 firms in the $2M-$5M range, 3 firms in the $5M-$10M range, 9 firms in the $10M+ range.
Among the 16 firms tracked, 88% lead or co-lead rounds, and 13% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best growth fintech & payments + biotech & life sciences investors combine domain expertise with an active portfolio in the space. Among these firms, 38% prefer warm introductions, and the average firm has 38 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.