38 VC firms investing in gaming and healthcare & digital health at the Series A stage.
F4 Fund tracks 38 VC firms that actively invest in gaming + healthcare & digital health at the Series A stage, with check sizes ranging from $20K – $350M (median: $2.8M – $2.8M). As of June 2026, and 87% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,358+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Atinum Investment Atinum Investment identifies and invests in companies solving fundamental problems through technology innovation and market disruption. The firm specializes in growth-stage startups and paradigm-shifting companies across diverse sectors. | $500K – $10M | 56 | Leads | Active | ~2 wks | Open |
| 2 | ▶ Makers Fund Backing builders of the future of interactive entertainment. We invest across games, content, platforms, and ecosystem technologies with conviction that visionary founders are driving transformation in how we play, watch, create, and live. | $500K – $5M | 158 | Leads | Active | ~2 wks | Open |
| 3 | ▶ Delphi Ventures Delphi backs extraordinary founders at the bleeding edge of technology, operating at the intersection of crypto/blockchain and deep tech. Crypto is freedom technology enabling human coordination at scale without intermediaries. With AI and atomic breakthroughs, these forces will disintermediate legacy models and form foundations of civilizational change over the next decade. San Mateo, California | $50K – $25M | 33 | Leads | Active | ~1 wk | Open |
| 4 | ▶ Supernode Global We invest in early-stage consumer and B2B technologies that meaningfully enhance personal and professional lives. We back application-layer software with consumer-grade UX that people actually use every day. Our focus: Wellbeing (health & vitality, life optimization, community & social) and Productivity (intelligent workflows, creative enablement, professional augmentation). | $500K – $3M | 27 | Leads | Active | ~1 wk | Req'd |
| 5 | ▶ Muse Capital We invest in traditionally overlooked and untapped consumer technology opportunities across the future of how we care, play, and live. Demographic shifts (aging population, female wealth, cultural diversity) create massive new markets. We don't chase hype—we invest in what should exist. Los Angeles | $100K – $1M | 25 | Both | Active | ~2 wks | Open |
| 6 | ▶ Montage Ventures Montage Ventures aims to support radical thinkers who are bringing new ideas and platforms to foster change within the financial services, commerce and health sectors, leveraging AI as a key transformative agent. | $250K – $1M | 51 | — | 2mo | — | — |
| 7 | ▶ Spacecadet Ventures Founders building the possibly impossible deserve capital plus marketing support. Great technology combined with exceptional storytelling and narrative development creates world-changing moonshots. We provide both the capital and the story-telling expertise to help founders achieve escape velocity. New York | $250K – $1M | 99 | Leads | Active | ~2 wks | Open |
| 8 | ▶ SMOK Ventures CEE founders (Polish, Ukrainian, Romanian, etc.) are building the next generation of global software companies. We partner with experienced operators who combine deep industry expertise with serial entrepreneurship. Geographic arbitrage: exceptional technical talent in CEE with lower burn rates, global ambition. We provide early capital plus connections to Silicon Valley for follow-on funding (80% of portfolio follow-ons from SV/Europe/Asia). Goal: $500M+ exits in 8-10 years. | $100K – $1M | 35 | Leads | Active | ~1 wk | Open |
| 9 | ▶ Upfront Ventures Early investors and long-term partners. We back exceptional founders solving real problems across sectors. When you hit a bump in the road, we're there solving problems alongside you with operational expertise and network leverage. | $1M – $15M | 46 | Leads | Active | ~2 wks | Req'd |
| 10 | ▶ SNÖ Ventures Nordic-focused VC providing global access and local support for the region's most daring tech pioneers. We back transformative companies across gaming, AI, software infrastructure, and emerging technologies with founders who have global ambitions and shipping experience. | $250K – $5M | 21 | Leads | 2mo | ~2 wks | Open |
| 11 | ▶ MANTIS Venture Capital Mantis invests opportunistically in Seed and Series A technology-enabled startups, leveraging deep social capital across tech, media, entertainment, and finance to provide unmatched GTM support. The firm is founder-obsessed and differentiates through celebrity network access, customer introductions, talent acquisition help, and brand amplification. Santa Monica | $500K – $3M | 113 | Both | Active | ~2 wks | Open |
| 12 | ▶ Headline We invest in top founders everywhere building the next generation of technology companies. We provide capital, operational expertise, and a truly global platform to scale with hands-on support through specialized teams. | $2M – $50M | 51 | Leads | Active | ~2 wks | Open |
| 13 | ▶ Greycroft Partnering with brilliant founders to upend the status quo by investing in AI-driven software, sustainability technologies, and innovative consumer brands. We believe AI will dominate software over the next decade, and we seek to support founders reimagining industries across all three sectors. New York | $2M – $100M | 48 | Leads | Active | ~2 wks | Open |
| 14 | ▶ Presence Capital VR and AR are transformative technologies. We invest in early-stage companies creating novel experiences, content, and enabling infrastructure. We bring deep operational expertise from building FarmVille, Unreal Engine, Gears of War, and leading HTC's VR initiative. San Francisco | $25K – $100K | 21 | Follows | Active | ~2 wks | Req'd |
| 15 | ▶ WXR Fund Gender-diverse teams building spatial computing and AI companies represent the best founders and the next computing paradigm. Female-founded teams outperform all-male teams by 63% and are systematically underfunded. San Francisco | $100K – $1M | 20 | Leads | Active | ~1 mo | Req'd |
| 16 | ▶ Dreamers VC Where capital becomes culture. Dreamers VC bridges established Japanese corporate investors with early-stage US companies by combining entertainment, sports, and technology expertise. The fund leverages celebrity networks, entertainment channels, and Japanese corporate partnerships to amplify storytelling and enable cross-cultural market expansion. Los Angeles | $250K – $5M | 43 | Both | Active | ~1 mo | Req'd |
| 17 | ▶ Hummingbird VC We back outliers of the outliers - founders with unreasonable ambition who can filter out 95% of conventional VC advice. We seek category-defining companies aiming for $10B+ outcomes, not incremental improvements. Our conviction is deep, selective, and global. We don't meddle - we provide brutal honesty, talent upgrades, and capital for survival through near-death moments. London | $500K – $50M | 34 | Both | Active | ~2 wks | Open |
| 18 | ▶ Banana Capital Identify resilient, obsessed founders with exceptional conviction and a chip on their shoulder building category-defining products with defensible distribution. Target founders to work with for the next decade, seeking businesses with clear revenue prospects in large markets. Ann Arbor, Michigan | $25K – $300K | 22 | Leads | Active | ~1 wk | Open |
| 19 | ▶ Andreessen Horowitz Backing the builders of the next layer of computing across AI infrastructure, defense, biotech, and American dynamism. Former 'Software is Eating the World' thesis evolved to 'AI is Eating Software'. Partners with technical founders building foundation models, cloud systems, and infrastructure for the AI era. Menlo Park | $1M – $200M | 48 | Both | Active | ~2 wks | Open |
| 20 | ▶ Bling Capital The hardest thing in seed is finding product-market fit. We help you find it. If you already have product-market fit, we will help you scale. We partner with exceptionally ambitious founders for the long run and provide capital combined with operational expertise through our 100+ member Product Council. San Francisco | $500K – $3M | 33 | Leads | Active | ~2 mo | Open |
| 21 | ▶ Incubate Fund Incubate Fund provides unwavering hands-on support to visionary entrepreneurs from the earliest stages. As Japan's leading seed-stage VC, they go beyond capital to provide operational support, founder counseling, talent recruitment, and business introductions. Core question: 'Does this action lead to impact?' Tokyo | $200K – $2M | 25 | Leads | Active | ~1 mo | — |
| 22 | ▶ Sweet Capital Early-stage consumer technology — mobile, social, marketplaces, media, consumer health, and consumer fintech. Built by King.com founders to back ambitious consumer-native teams with engagement DNA. London | $250K – $2M | 12 | Both | Active | ~1 mo | Open |
| 23 | ▶ FirstMark We back disruptive founders building category-defining companies. Our approach is founder-first, long-term, and deeply operational. We take the longest view in the room, operate with excellence and integrity, stay curious at the bleeding edge, and invest heavily in building community. New York | $250K – $10M | 32 | Leads | Active | ~2 wks | Req'd |
| 24 | ▶ Origins Fund Origins backs legendary consumer founders with an unfair advantage from pre-seed to series A. We combine venture capital with the power of celebrity and athlete influence, providing not just capital but access to 160M+ social media followers through our limited partners for user acquisition and brand amplification. New York | $100K – $500K | 21 | Leads | Active | ~2 wks | Req'd |
| 25 | ▶ Rainfall Ventures We invest in world-class founders solving significant problems. We prioritize founder quality, founder-problem fit, and values-aligned partnerships. We help exceptional founders become category leaders early, before they become obvious trends. Los Angeles | $500K – $5M | 41 | Leads | Active | ~2 wks | Req'd |
| 26 | ▶ Lightbox Early-growth brands that India will obsess over tomorrow — technology-led consumer businesses where product is the champion and tech a catalyst. Lightbox takes concentrated bets in select entrepreneurs and partners beyond capital through deep operational involvement. Mumbai | $5M – $30M | 20 | Leads | Slowing | ~2 mo | Open |
| 27 | ▶ Coatue The best investment opportunities emerge at the intersection of innovation and scale. We invest across the full lifecycle from seed to public markets, focusing on technology companies that will transform sectors globally with particular conviction in AI-enabled platforms and infrastructure. New York | $1M – $100M | 30 | Both | Active | ~2 wks | Open |
| 28 | ▶ HOF Capital HOF Capital invests in relentlessly ambitious founders building world-changing technologies that accelerate abundance: sustained technological progress that expands access to opportunity, health, and economic prosperity. Its current public thesis emphasizes AI and agentic systems as amplifiers of discovery, engineering, and knowledge creation, alongside frontier infrastructure and applications that can shorten scientific and technological invention timelines. New York | $500K – $10M | 29 | Both | Active | ~2 wks | Req'd |
| 29 | ▶ Debut Capital Early-stage venture capital for IT and Biotech companies in Colorado Front Range and Mid-Atlantic. Focus on experienced founding teams solving important problems with potential for significant financial returns. Patient capital approach with operational support and deep regional networks. New York | $500K – $5M | 48 | Leads | Active | ~2 wks | Req'd |
| 30 | ▶ Sand Hill Angels Sand Hill Angels backs seed-stage, high-tech companies with large and growing markets, well-defined problems, disruptive solutions, defensible technology, and strong teams with demonstrated ability to execute. The group leverages 145+ experienced angels to provide capital, mentorship, and network access across the Silicon Valley ecosystem. Mountain View | $50K – $2M | 30 | Follows | Active | — | Open |
| 31 | ▶ Expa We build category-defining companies through a combination of design, product, operations, and capital. We identify market gaps, pair brilliant founders with Expa's studio resources, and help them build companies that reshape entire industries. San Francisco | $500K – $5M | 60 | Leads | Active | ~1 wk | Open |
| 32 | ▶ Goodwater Capital Consumer technology has the power to measurably improve billions of lives across the globe. We invest in exceptional entrepreneurs building digital utilities that provide better access to housing, healthcare, food, financial services, transportation, education, and entertainment globally. Burlingame, California | $5M – $50M | 29 | Leads | Active | ~1 mo | Req'd |
| 33 | ▶ Elevate Ventures Elevate Ventures partners with innovation-driven founders to provide strategic capital, mentorship, and ecosystem access. Founded by a former founder (Governor Mitch Daniels), the firm believes the best founders exhibit grit, creativity, and coachability. They invest across all sectors and geographies but maintain primary focus on Indiana and Great Lakes Region entrepreneurs building cross-sector innovations. Indianapolis | $20K – $2M | 28 | Leads | Active | ~1 mo | Open |
| 34 | ▶ TenOneTen Ventures Technical founders backing technical founders. We invest early in technical teams transforming major industries facing existential threats and tremendous opportunities. We target essential sectors—healthcare, logistics, real estate, manufacturing—where technical innovation solves critical problems. Los Angeles | $250K – $5M | 24 | Leads | Active | ~2 wks | Open |
| 35 | ▶ Insight Partners Software founders need more than capital to scale successfully. Insight Partners combines investment capital with hands-on operational expertise, embedded teams, and network access to accelerate company growth across all stages. New York | $10M – $350M | 28 | Leads | Active | ~1 mo | Open |
| 36 | ▶ Gaingels Equity of access and representation in venture capital delivers positive returns. Diverse and underrepresented (including LGBTQ+) leaders of high-growth companies deserve capital access. When these founders succeed, they influence ecosystems and open doors for historically excluded groups. New York | $200K – $500K | 29 | Follows | Active | ~2 wks | Open |
| 37 | ▶ Evolution Venture Capital Partners Culture-Tech companies that disrupt and define how we live, work, play, and interact with the world every day. We invest in passionate founders building transformative products that change cultural behaviors. New York | $500K – $6M | 28 | Leads | Active | ~1 wk | Open |
| 38 | ▶ Animal Capital Leverage creator economy and influencer networks to add tangible value to early-stage companies. Invest in ambitious Gen Z founders building consumer products with high influencer marketing potential. Influencer partners actively support portfolio companies with marketing, business development, and strategic partnerships. | $500K – $5M | 11 | Follows | Active | ~1 mo | Req'd |
Investors on this page also frequently invest in these sectors
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What other sectors do these firms also invest in?
Firms that frequently co-invest with investors on this page
F4 Fund tracks 38 VC firms that actively invest in gaming + healthcare & digital health at the Series A stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for series a gaming + healthcare & digital health investors is $2.8M – $2.8M, with a full range from $20K – $350M. The distribution breaks down as: 4 firms in the <$500K range, 5 firms in the $500K-$1M range, 7 firms in the $1M-$2M range, 9 firms in the $2M-$5M range, 4 firms in the $5M-$10M range, 9 firms in the $10M+ range.
Among the 38 firms tracked, 87% lead or co-lead rounds, and 11% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best series a gaming + healthcare & digital health investors combine domain expertise with an active portfolio in the space. Among these firms, 33% prefer warm introductions, and the average firm has 40 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.