Best Pre-Seed Healthcare & Digital Health + Logistics & Supply Chain Investors 2026

We seed high-growth startups with unstoppable drive in healthcare, fintech, and logistics. Founder does not have a stereotype—it is about drive, character, and conviction. We provide capital, operational support, and genuine partnership.

We invest in companies that solve for non-consumption, plug infrastructural gaps and democratise prosperity in Africa, by eliminating the barriers to access and reducing the costs of delivering goods and services.

The entrepreneurial journey from zero to one is isolating and difficult. By becoming an extension of portfolio founders' teams, we can build the next generation of successful B2B SaaS companies. We invest in founders first, companies second. Technology should be human-centered, founder-first, and focused on solving real market problems.

We invest in people and give them freedom and support needed to execute their vision. We rely on data to measure, manage and monetize. We encourage bold ideas which are true, firm, confident, strong and resilient. We praise agility - the key to success in a competitive environment. We invest in early-stage companies operating with clear focus on sustainability in every dimension: business practices, unit economics and environmental impact.

Group of founders, operators, and ecosystem builders investing in the next generation of Latin American startups. Sector-agnostic, founder-first approach with an 8-day decision commitment and deep operator network across the LATAM ecosystem.

Partner with exceptional founders at the very inception of their entrepreneurial journey. Our proprietary data-driven technology identifies promising founders beyond immediate networks. We focus on teams with strong product sense and bottoms-up growth potential in data-driven software categories.

Be the most helpful investor. Back exceptional Australian founders building technology companies with strong founder-market fit and large addressable markets.

We invest in technology companies that reduce friction at scale. Companies like Amazon and Uber fundamentally transformed industries by eliminating unnecessary complexity. We're looking for B2B software founders solving real enterprise problems, especially with AI.

MS&AD Ventures partners with visionary entrepreneurs to create innovative solutions across insurance, financial services, healthcare, and sustainability. Backed by the 5th largest global insurance conglomerate, they bring capital plus global distribution across 47 countries. They move fast (2-week decisions), focus on partnerships over ownership, and help companies scale internationally.

Overlooked markets where distribution advantage compounds. Founders with deep domain empathy build durable moats. B2B software rebuilding industries through core workflows, data connectivity, and embedded intelligence.

We are long-term business partners to founders. We operate as an investment partnership focused on founders building category-defining African technology companies, with tight founder-investor-LP alignment and deep operational support.

Seed capital is the foundational layer in building enduring companies. We back bold, gritty founders applying AI and machine intelligence to solve the world's toughest challenges in enterprise and industrial sectors. By end of decade, software + hardware + AI will drive ubiquitous automation in every industry. We partner with visionary founders tackling hard technical problems in regulated, complex domains.

NVP backs early-stage founders using vertical AI and enterprise software to modernize under-digitized legacy industries, especially healthcare, industrials, financial services, workforce management, commerce enablement, legal workflows, and sales and marketing operations.

Back incredible founders with strong domain knowledge tackling real, durable problems with high growth potential in large and growing markets. Specialty in B2B software and automation for legacy industries — financial services, manufacturing, insurance.

Entrepreneurship is one of the most powerful engines for impact and value creation. Back founders with purpose, grit, and urgency building consequential companies solving significant problems in healthcare, fintech, and industrials. Lead first checks, stay in trenches, and scale together.

Supply Change Capital invests at the intersection of food, climate, and culture. We back early-stage technology transforming the food supply chain's foundational infrastructure - from supply chain resilience and logistics to health/nutrition innovation and labor automation. We believe the global food system ($10T industry) is least modernized sector globally, requiring urgent technological transformation to address climate impact (1/3 of GHG emissions), health crises (50%+ with diet-related chronic disease), and labor equity. We invest with dual lenses: climate impact (emissions reduction, soil health, biodiversity) and culture (supporting diverse founders who deliver 30% higher returns despite underinvestment). As former operators, we partner with founders not just with capital but operational expertise, impact metrics frameworks, and access to extensive advisor network of industry veterans.

Extraordinary companies are built by driven founders whose mission to improve the health of people and planet is inseparable from their product. We partner with technical founders building technology solutions to the world's most important challenges across climate, health, biotech, and enabling technologies.

Back underestimated founders with something to prove who are disrupting large markets. Emphasizes geographic arbitrage in emerging markets (Africa, LATAM, Asia) where founder quality is exceptional but capital access is limited.

Back technology founders solving foundational and transformational problems across Africa and MENA. Focus on underserved markets with significant TAM. Support entrepreneurs demonstrating grit, creativity, growth mindset, and conviction. Combine global capital markets access with deep local operational expertise.

Early-stage founders using AI and frontier technology to reinvent enterprise and security markets. We seek technical founders who deeply understand their problem domain, have operating experience at scale, and are committed to responsible AI development. We provide not just capital but hands-on operational support through our Building Partners model.

We partner with experienced, technical founders to build category-leading companies in Vertical AI, Fintech, and Healthcare. We believe go-to-market execution and distribution are the real momentum builders in today's market where technical barriers to entry have lowered. We provide specific, measurable value tied to revenue, particularly helping founders land their first enterprise customers.

The future of cities will be shaped by entrepreneurs who can navigate complex regulatory environments. We provide seed capital and regulatory/policy expertise to startups enhancing the livability, sustainability, and economic vitality of cities.

Partner with spiky founders building category-defining companies using novel technological approaches. Focus on AI-driven innovation across alternative architectures, custom software, research assistants, TechBio, infrastructure, and enterprise applications. Provide capital, operational support, strategic guidance, and network access for founders with unique insights and deep technical expertise.

Africa's future prosperity depends on technological innovation across foundational sectors. Brilliant entrepreneurs applying technology to solve Africa's most pressing problems build world-class businesses while generating exceptional returns. Commercial rigor combined with social impact creates sustainable value.

The best B2B software companies emerge when founders combine deep domain expertise with technical sophistication to build solutions addressing inefficiencies in underserved verticals. We invest in technical founders and experienced operators who understand their target market intimately.

Technologies that change and are changed by consumer behavior. We invest at the intersection of innovation and consumer behavior, providing not just capital but direct access to corporate partners (Mastercard, Estée Lauder, TJX), 370+ mentors, and retail distribution.

Digital transformation is everywhere except where it matters. The world's essential physical industries—manufacturing, supply chain, transportation, healthcare infrastructure, and energy—have failed to keep pace with technological innovation. These industries are ripe for transformation through digitization, automation, and physical AI. We partner with experienced operators and technical founders to rebuild critical infrastructure.

Founders closest to the problem—particularly those from historically overlooked communities—are best positioned to solve it. We invest at the intersection of innovation and inclusion in the building blocks of shared prosperity: economic mobility, healthcare access, and community infrastructure. Perspective and proximity are power.

Story invests in the building blocks of automated systems across three interconnected layers: sensory systems (data capture), data processing (organization and structure), and machine intelligence (applications and decision-making). We believe the most impactful problems require the most innovative solutions, and we partner with founders pursuing audacious, challenging businesses because that's what it takes to create lasting impact.

Mercury backs disruptive AI and Blockchain-enabled startups outside Silicon Valley, with a focus on capital-efficient founders in the Central US reimagining core industries including fintech, enterprise software, healthcare, energy, manufacturing, and logistics through their five investment themes: Work, Build, Journeys, Data, and Power.

Backs extraordinary pre-seed and seed technology founders, with hands-on technical, operational, finance, and leadership support delivered with a collaborative co-founder attitude.

Empowering visionary entrepreneurs to build unique solutions that reshape how Indians live, work, consume, and transact. Kalaari backs potential over pedigree — first-time founders welcome — focusing on tech-driven Indian market opportunities from Pre-Seed through Series A.

Partner with elite founders building transformational technologies that create lasting economic and societal value. Focus on Smart Enterprise across five sectors: Logistics, Life Sciences, Healthcare, IT Infrastructure, and Government/Defense. Invest in platforms that enable human experts to solve non-linear problems through data integration and network effects.

See beyond borders. Back exceptional founders who think differently, refuse to follow conventions, and are willing to build defensible, data-driven products. Great talent exists everywhere, and the venture capital industry can be transformed from within.

Back founders building startups that reimagine the future across healthcare, logistics, fintech, and sustainable innovation. Investment thesis emphasizes mission-driven founders solving meaningful problems with bold, long-term vision.

Argon leads or co-leads pre-seed rounds in Intelligent Industry Solutions: vertical software platforms that combine industry insight with deep tech, machine learning, and data to improve productivity, efficiency, and enterprise value.

Bespoke Capital for Enduring Impact. Gobi invests where capital alone is insufficient — requiring deep local relationships, sustained engagement, and informed judgment across Asia's diverse and complex markets. They focus on technology companies solving structural inefficiencies across underserved Asian markets, from fintech to deep tech to sustainable infrastructure.

Robotics represents a distinct, nuanced asset class requiring specialized operational insight. Physical AI breakthroughs are making once-theoretical use cases commercially viable. Investors need deep sector expertise to manage associated risks and unlock real value. Robotics is fundamentally different from software venture investing.

Humanizing deep tech by bringing advanced breakthrough technologies to where the people are and maximizing the value they generate for solving humanity's most critical crises. We invest in companies addressing climate, manufacturing labor shortages, healthcare costs, sustainable food production, and computing infrastructure.

The next generation of significant technology companies will be built by Black founders and diverse entrepreneurs who have historically been locked out of access to venture capital. We back exceptional Black and diverse-led teams building scalable technology solutions, with the conviction that diverse teams drive innovation and create extraordinary returns.

Kindred backs visionary and relentless founders building the future using technology and science at the earliest stages, often helping form companies before they exist. With Kindred Ventures IV and Kindred Selector II, the firm is emphasizing the novel intelligence frontier: AGI-capable models and harnesses that extend human capabilities, new AI-native consumer and enterprise experiences, physical AI, compute, infrastructure, energy, science, outer space, and inner space.

Global industry is undergoing its most profound technology transformation in over a century. Calibrate backs visionary founders scaling proven deep tech — AI, computer vision, robotics, automation — to transform major sectors including manufacturing, logistics, healthcare, agriculture, and enterprise services. They invest in companies generating early recurring revenues and ready to scale, seeking market-ready deep tech with large-scale applicability.

We invest in founders transforming how money and goods flow across the economy. We focus on tech for traditional sectors - modernizing underserved industries through vertical AI and software solutions. We partner with operators who deeply understand industry pain points.

Empower audacious founders who challenge norms and leverage technology to transform industries. We believe in first-time founders with scrappy outsider mentality and narrow niche focus. Silicon Valley expertise combined with deep emerging market knowledge across three continents.

Day 0 venture capital applied by a deep operator. Better Capital invests at the earliest stage where ambiguity is highest and operator judgment adds the most value. Solo GP model keeps conviction high and enables deep engagement with 20-25 companies at critical inflection points.

Bold, visionary African founders solving Africa's biggest challenges represent global business opportunities. We combine capital, operational support, and community to build sustainable, continent-scale businesses.

Back Latin American founders with global ambitions who use technology and AI to solve hard, inefficient markets in fintech, commerce, human capital, health, smart cities, and related large regional opportunities.

Builds AI companies from inception alongside recruited CEOs, acting as an AI R&D studio that sources ideas with large corporates to deliver agentic-AI ventures with built-in customers and traction. Fund II focused on application and software infrastructure layers with emphasis on enterprise adoption and agent protocols.

Backs globally ambitious technology companies from pre-seed and seed through selected growth rounds using specialist EMEA sector teams and a platform model for capital, customers, talent, follow-on investors, and operational support.

Invest in Southern California's best founders earlier than anyone else. No idea is too early. We fund companies earlier than most VCs, providing not just capital but hands-on support and operational expertise. Our founder-first philosophy and No Ghosting Rule ensure responsive, engaged partnerships.

Pan-African fund solving the significant funding gap in Seed and pre-Series A investment. Backing ambitious African founders tackling critical continental challenges with operational support and investor network.

Backs early-stage B2B founders building vertical AI solutions that automate administrative and operational workflows in underserved industries. Focuses on seed-stage companies with strong founder-market fit and clear unit economics.

Yonder invests in early-stage marketplaces that build new economies. We provide first institutional checks to marketplace founders with deep problem intimacy and operational experience. We combine capital with strategic introductions, operational coaching, and access to a network of 50+ marketplace operators and marketplace leaders.

Anabel Paksoy actively looks to invest in early-stage startups at Day 0, providing hands-on support tailored to the founder's unique needs. She focuses on founders who are passionate about solving specific problems, and investments are made quickly to take advantage of timely opportunities.

Back the quirky underdog pursuing seemingly impossible ideas. Frontier tech (aerospace, biotech, climate, robotics, crypto, AI, VR/AR) will create the next generation of legendary companies. Technical founders with deep domain expertise can solve the hardest problems in physics, chemistry, and computing.

Backing immigrant entrepreneurs building companies in Europe. Immigrants account for ~50% of US and ~40% of UK unicorns. NLV spots and supports this talent before the market catches up, investing unconditionally as the first check before lead VCs are in place.

Invest in technical storytellers—founders with deep technical depth, exceptional communication skills, and strong execution velocity. Fund innovation in traditionally overlooked industries (Clipboard Companies) by applying modern technology while respecting domain expertise.

We invest in paradigm shifters—truly disruptive technologies that change our perspective of the world. We believe in missionary founders committed to their vision, and we focus on business-team-idea-timing fit, not just product-market fit. We target transformative companies across defense, climate, fintech, legal tech, and emerging domains.

Extraordinary founders execute faster when isolated from distractions and provided intensive on-site support. We seek junkyard dogs with high agency, non-obvious vision, delusional optimism, and execution discipline. Category matters far less than founder quality.

Technological innovation is unevenly distributed. The hottest, most visible sectors attract talent and capital, while overlooked industries hide massive value creation opportunities. We back unconventional founders disrupting unglamorous, technology-inefficient, long-standing industries.

We invest in the earliest pre-seed startups led by founders outside typical networks, selling into large and growing markets, with unique approaches or insights. We focus on under-networked, execution-focused founders—introverted technologists, industry veterans, and heads-down operators—who create outsized value through systematic sourcing and deep technical partnership.

Real estate has been stagnant for 50 years despite massive innovation in other industries. Shifting demographics, transportation changes, and evolving preferences are forcing modernization. We back visionary entrepreneurs building solutions across construction, property management, residential finance, and retail that will improve quality of life, work, and community.

Scale value and drive efficiency in Latin American emerging markets where information asymmetries and service gaps create opportunities for bold, visionary founders to disrupt and lead.

We invest in world-class founders solving significant problems. We prioritize founder quality, founder-problem fit, and values-aligned partnerships. We help exceptional founders become category leaders early, before they become obvious trends.

Technology companies are becoming intertwined with the global economy more so than ever before. The most compelling founders build businesses through a broader world view. White Star Capital backs globally ambitious entrepreneurs at Series A, B, and Seed stages across North America, Europe, and Asia, helping them scale internationally through deep local presence on three continents.

The best investment opportunities emerge at the intersection of innovation and scale. We invest across the full lifecycle from seed to public markets, focusing on technology companies that will transform sectors globally with particular conviction in AI-enabled platforms and infrastructure.

Innovative technology entrepreneurs exist globally, particularly in emerging markets, and deserve access to world-class mentorship, infrastructure, and Google's vast product ecosystem. We support founders who have proven product-market fit in their home markets and are ready to expand internationally.

Lightbank invests in disruptive technology companies led by great founders in dynamic markets with world-class products. The firm believes exceptional founders and opportunities exist everywhere, especially in overlooked geographies like the Midwest. We partner with early-stage founders and provide operator-heavy support beyond capital.

Inception-stage VC backing experienced founders building B2B autonomous agentic AI from day zero. Leverages Salesforce alumni network to provide portfolio companies with enterprise distribution and operational support.

Invest in outsiders—mission-driven, non-traditional founders in off-coast locations building hardware, deep tech, logistics, or legacy-industry companies. Reject the Stanford/Google/Bay Area formula in favor of exceptional founders who don't fit traditional VC molds.

Latino founders represent an underserved but exceptionally talented segment of the entrepreneurial ecosystem. We invest in visionary founders who combine bold ideas with execution excellence to build scalable, high-impact businesses that create both economic and social value. We believe institutional capital paired with strategic partnership from Fortune 100 executives and operating experts can unlock the full potential of Latino-led innovation.

Investing in subject matter experts shaping the future of their industries. We lead with our values and build trust through action. We believe the best founders have deep industry expertise and need tireless operational support, not just capital. We partner with founders for the long term, staying engaged 24/7.

Invest in and scale technology businesses where artificial intelligence and data capabilities drive impact and market growth across Latin America. Latin Leap aims to help Spanish-speaking Latin America 'leapfrog' through technology investments tailored to emerging market needs, while also bridging international tech companies into the region.

Entrepreneurs who work constructively with government to harness its unique strengths—scale, credibility, regulatory power, data, and funding—enjoy asymmetric advantages. 24% of venture-backed unicorns used government support. We partner with founders to unlock government as a growth lever.

Gateway Capital partners with tenacious, resourceful founders building solutions to real-world problems in overlooked markets. We believe that financial returns and social returns are not mutually exclusive, and we invest where others hesitate - focusing on underestimated regions and low-to-moderate income communities.

Exceptional talent and disruptive ideas know no borders. We invest in emerging innovation hubs where competition is low, valuations are favorable, and founders are capital-efficient. We focus on three transformative themes: Future of Work (hybrid/remote, upskilling, AI automation), Future of Care (healthcare access, value-based care, longevity tech), and Emerging Tech (AI agents, cybersecurity, clean tech). We provide not just capital but operational, sales, policy, and strategic expertise to accelerate growth.

Entrepreneurs, not VCs, build great companies. We invest early in great & passionate entrepreneurs and serve as long-term partners. Available 24/7 to help founders with mentorship, product-market fit, fundraising, business development, customer acquisition, talent sourcing, and strategic partnerships.

We build category-defining companies through a combination of design, product, operations, and capital. We identify market gaps, pair brilliant founders with Expa's studio resources, and help them build companies that reshape entire industries.

We invest at the earliest stages and partner with exceptional entrepreneurs from idea to IPO. We stay small by design to remain aligned with founders. We're sector-agnostic, conviction-driven, capital-efficient, and believe in founder/market fit and intrinsic value over hype.

Backing the best founders, not just the best-connected. We assess founders on their qualities, not CV or past experience. We focus on founders building solutions for climate equity, economic empowerment, and healthy ageing.

A majority of the data our brains analyze is visual. Therefore, the majority of the data AI will analyze will also be visual, spanning the light and electromagnetic spectrums across all sectors. We thrive on collaborating with deep technical teams who leverage computer vision, machine learning and artificial intelligence to analyze visual data.

We connect innovative startups with 550+ corporate partners who have real business problems to solve. Our unique position in the ecosystem creates a flywheel of pilots, proofs-of-concept, enterprise customers, and follow-on capital. We back founders solving real market problems with credible corporate validation.

We empower visionary founders building transformative tech companies. We are thesis-driven partners to exceptional entrepreneurs creating long-term impact across FinTech, ClimateTech, and Global Tech sectors.

Empowering entrepreneurs to reimagine the way we live and work by investing in daring technology companies challenging the status quo with permanent capital, lifelong sparring partnership from pre-seed through IPO and beyond.

Lead pre-seed and seed rounds in Canadian B2B software and AI-enabled vertical workflow companies with an initial product in market, early product-market-fit signals, and ambition to scale across North America or globally.

Leading global companies that leverage technological innovation across public and private markets. Proven founders (especially ex-Googlers, AWS, Stripe) with large TAMs (billions+), product-led growth, and global ambitions. Conviction-based investing post-2022 correction emphasizing quality over quantity.

Technical founders backing technical founders. We invest early in technical teams transforming major industries facing existential threats and tremendous opportunities. We target essential sectors—healthcare, logistics, real estate, manufacturing—where technical innovation solves critical problems.

The primary constraint for seed-stage, science-based entrepreneurs is access to experienced business judgment. CDL provides objective-based mentoring from accomplished entrepreneurs, angels, and scientists to help founders prioritize tasks and de-risk their businesses.

Serious founders building must-have technology for mission-critical industries. We focus on B2B software companies digitizing legacy industries and transforming established workflows. Specializing in seed-stage, where hands-on operational support, sales acceleration, and capital strategy matter most.

Rule30 uses a fully algorithmic decision engine to identify outlier founders at pre-seed and seed stages across Europe and North America. The fund removes human bias by analyzing founder experience, educational background, network evolution, and career trajectory — excluding names and photos. The algorithm ranks founders into top 10%, 3%, and 0.1% tiers. An index-style strategy of 75-85 bets targets ≥3x minimum returns with 97.5% confidence.

Backs European pre-seed and seed founders building technologies for Energy, Industry, and Resilience, especially energy transition, industrial automation, practical AI for infrastructure, manufacturing, logistics, energy grids, and critical systems.

Startups positioned as transformation partners with Fortune 500 corporates create the most impactful solutions. We believe the next generation of market leaders will emerge through collaborative innovation between startups and incumbent enterprises, supported by global expertise and capital.

Culture-Tech companies that disrupt and define how we live, work, play, and interact with the world every day. We invest in passionate founders building transformative products that change cultural behaviors.

Back the world's most ambitious and transformative entrepreneurs capable of building world-defining companies over 20+ years. Invest in founders with independent thought and first-principles vision to solve humanity's biggest problems across all sectors and geographies.

Democratize access to venture capital by building large syndicates of non-traditional LPs. Invest across all stages, sectors, and geographies based on founder quality and market conviction, not category restrictions. Enable 2,000+ diverse co-investors to participate alongside marquee firms like Sequoia and Andreessen Horowitz while maintaining founder-friendly economics.

Operator-led fund investing in ambitious founders building transformative AI applications. We partner with technical founders who understand AI/ML deeply and are solving real customer problems with capital efficiency. Great product is always the best marketing.

IGC pioneered the Reverse VC™ model — starting with corporate demand rather than capital deployment. Their ReverseVision platform identifies what Global 5000 companies want to buy, then matches emerging tech founders to those demand signals. Investment flow: Demand → Commercialization → Valuation → Capital → Exit. This approach claims higher success rates, better deal terms, and reduced downside risk by replacing intuition with engineered outcomes.