28 VC firms investing in security & cybersecurity and healthcare & digital health at the Growth stage.
F4 Fund tracks 28 VC firms that actively invest in security & cybersecurity + healthcare & digital health at the Growth stage, with check sizes ranging from $100K – $350M (median: $17.5M – $17.5M). As of June 2026, and 93% lead or co-lead rounds. Rankings are based on F4's proprietary analysis of 1,358+ researched VC firms, scored by data completeness, portfolio depth, investment recency, and stage alignment.
| # | Firm | Check Size | Portfolio | Leads? | Activity | Decision | Intro |
|---|---|---|---|---|---|---|---|
| 1 | ▶ Index Ventures We invest in who you are, not just what you do. We back visionaries and game-changers with character and global ambition. We partner long-term with founders, providing capital, operational support, and deep conviction in their vision. San Francisco | $500K – $50M | 370 | Leads | Active | — | Req'd |
| 2 | ▶ Point72 Ventures Point72 Ventures backs ambitious founders building for big outcomes across critical domains. Going deep, not wide—the firm focuses on specialized investment theses in AI, Consumer, and Defense Tech, bringing deep sector insights, partnership, and hands-on support from seed to pre-IPO. New York | $250K – $50M | 203 | Both | Active | ~2 wks | Req'd |
| 3 | ▶ AVP Independent global investment platform backing capital-efficient, high-growth technology companies across Europe and North America. Multi-stage, multi-strategy approach from venture to pre-IPO. Transatlantic local teams provide unique advantage in bridging European and US growth. Paris | $1M – $150M | 63 | Leads | Active | — | Open |
| 4 | ▶ Northzone Category-defining entrepreneurs building fundamental shifts that upend entire industries. Focus on disruptive business models in energy transition, healthcare, AI, and consumer. Thesis values human relationships and founder-centric partnerships over financial metrics alone. London | $1M – $40M | 34 | Leads | Active | ~2 wks | Req'd |
| 5 | ▶ Radian Capital Radian Capital partners with software-driven B2B companies at scale, providing capital and hands-on operational support. They concentrate on select companies and go deep with each, emphasizing sustainable growth over growth at all costs. New York | $5M – $30M | 34 | Leads | Active | ~1 mo | Req'd |
| 6 | ▶ Lightspeed Venture Partners We partner with bold builders of category-defining companies from Seed to Series F and beyond. Depth of commitment, depth of relationships, and depth of belief distinguish us. Complete immersion, authentic partnership, and unwavering conviction through market cycles. | $1M – $300M | 51 | Leads | Active | ~2 wks | Open |
| 7 | ▶ Phoenix Court Phoenix Court partners with exceptional founders from pre-seed through public markets and beyond. The firm operates as a multi-stage, multi-fund group — LocalGlobe (seed), Latitude (growth), Solar (late-stage), and Basecamp (emerging managers) — built on the conviction that the best companies grow big not just in private markets but across their full lifecycle. Founded on purpose: 10% of profits and 2% of carry go to Phoenix Court Works, which is transitioning to the single largest shareholder in the firm. London | $500K – $20M | 28 | Leads | Active | ~1 mo | Req'd |
| 8 | ▶ Georgian Georgian invests in market-leading B2B software companies across the AI technology stack—from infrastructure and developer tools to enterprise applications and cybersecurity. They pair growth-stage capital with an in-house AI Lab of 20+ ML engineers who embed with portfolio companies post-investment. Toronto | $20M – $75M | 27 | Leads | Active | ~2 wks | Req'd |
| 9 | ▶ General Catalyst We back founders venturing beyond to build transformational companies that create positive, enduring change. Applied AI and global resilience are fundamental forces reshaping industries. | $2M – $50M | 38 | Leads | Active | — | — |
| 10 | ▶ Frontline Ventures The world's most successful B2B software companies require presence and success in both North America and Europe. Frontline specializes in facilitating frictionless transatlantic expansion, supporting founders with global ambition through a dual-fund strategy optimized for international growth. London | $250K – $20M | 24 | Both | Active | ~1 wk | Open |
| 11 | ▶ AirTree Ventures Big things start small. We invest at seed stage and see potential where others don't. We believe in your vision for your company's future, not as it exists today. We think in decades, not days, committing to walk the entire journey with founders to build iconic companies. We share Antipodean ingenuity with the world. Sydney | $250K – $20M | 64 | Leads | Active | ~2 wks | Req'd |
| 12 | ▶ MassMutual Ventures Build category-defining technology businesses that deliver strong investment returns while addressing pressing business challenges. Leverage Fortune 500 parent (MassMutual) assets including real estate portfolios, renewable energy assets, and capital networks. Boston | $2M – $10M | 23 | Both | Active | ~1 mo | Open |
| 13 | ▶ Bain Capital Ventures Ambitious founders solving fundamental problems across major industries. The next generation of transformational companies will be built on modern AI, secure infrastructure, and efficient commerce. We partner with technical founders with operator experience and compelling narratives. San Francisco | $1M – $20M | 28 | Leads | Active | ~2 wks | Open |
| 14 | ▶ Redpoint Depth-first venture investing through mastery in specific domains. We partner with bold builders challenging industry conventions, backing founders with technical depth and conviction to build enduring $1B+ companies. Complete immersion creates enduring companies. Menlo Park | $500K – $50M | 17 | Leads | Active | ~2 wks | Open |
| 15 | ▶ Menlo Ventures Menlo invests in transformative technology companies at multiple stages of early growth. We provide capital, operational expertise, and hands-on support to help founders build scalable businesses that change how we live and work. San Francisco | $500K – $20M | 16 | Leads | Active | ~2 wks | Open |
| 16 | ▶ Partech Partners We support ambitious founders solving large problems through technology across all stages. Independent thinkers who challenge conventional wisdom are our ideal partners. We provide not just capital but operational expertise, global networks, and hands-on support from day one through scale. Paris | $300K – $100M | 24 | Both | Active | ~1 mo | Open |
| 17 | ▶ GV (Google Ventures) GV backs innovative founders moving the world forward, operating on long time horizons and dealing in decades, not rounds. Since 2023, GV has accelerated its focus on AI-native companies across infrastructure, applications, healthcare, and developer tools — with approximately 80% of new European investments now in AI. San Francisco | $500K – $50M | 30 | Both | Active | ~1 mo | Open |
| 18 | ▶ Alumni Ventures We democratize venture capital by providing individual accredited investors with professional-grade access to elite venture opportunities. We leverage our massive 850,000+ community network and 11,000+ investors to create unique value for founders, sourcing and diligencing deals alongside top-tier VCs (a16z, Sequoia, Khosla) without leading rounds. Our network is our competitive advantage—it compounds value for all stakeholders. Manchester, NH | $250K – $5M | 58 | Follows | Active | ~2 wks | Open |
| 19 | ▶ Kleiner Perkins Partner with exceptional founders building transformative technology companies from inception to IPO and beyond. Our moral compass is serving humanity with technology and capital. We provide not just capital but operational support, network access, and board participation to maximize the potential of founders' ideas and make history. Menlo Park | $100K – $150M | 27 | Leads | Active | ~2 wks | Open |
| 20 | ▶ K5 Global K5 Global backs category-defining companies from inception to IPO. The firm leverages exceptional networks across media, entertainment, politics, finance, and technology to provide strategic value beyond capital. We believe the best companies are built by founders who can access world-class talent, capital, and strategic relationships. Los Angeles | $1M – $3M | 34 | Leads | Active | ~1 mo | Open |
| 21 | ▶ WndrCo WndrCo positions itself as 'the founders behind the founders,' combining strategic capital with deep operational involvement. Unlike traditional VCs, partners take formal operating roles (interim CEO, CFO, CPO) within portfolio companies. This approach leverages the co-founders' proven track record: Sujay Jaswa scaled Dropbox from $18M to $10B as Business Founder/CFO, and Jeffrey Katzenberg transformed Disney Studios and built DreamWorks. The firm invests across all stages through three strategies: Build (acquiring underappreciated tech companies), Venture (leading post-PMF rounds), and Seed (very early checks). Focus areas are Future of Work, Cybersecurity, Developer Infrastructure, and Consumer Technology, with increasing emphasis on AI applications. Beverly Hills, California | $100K – $10M | 32 | Leads | Active | ~2 wks | Req'd |
| 22 | ▶ Foundry Group We invest in startups and venture funds, creating a symbiotic network that propels innovation. Our approach is characterized by long-term thinking and a 'give first' philosophy. Boulder, Colorado | $500K – $10M | 26 | Leads | Active | ~1 mo | Req'd |
| 23 | ▶ Mangusta Capital Mangusta backs founders building mission-critical capabilities at the intersection of vertical AI and consumer disruption. Three investment filters: Domain Depth (vertical-specific expertise), Defensibility (proprietary data + systems integration), and Distribution (embedded GTM). The firm believes vertical AI co-pilots that augment domain experts — rather than generic AI — represent the most durable and defensible category. San Francisco | $1M – $20M | 14 | Both | Active | ~1 mo | Req'd |
| 24 | ▶ IVP We supercharge growth in breakout companies, converting momentum into market dominance. We invest exclusively at Series B and beyond in companies that have achieved product-market fit and are ready to scale from millions to hundreds of millions in revenue. San Francisco | $1M – $25M | 31 | Leads | Active | ~2 mo | Req'd |
| 25 | ▶ Rosecliff Ventures We seek to create positive economic impact and long-term value by providing lifetime support to companies from seed through late-stage equity and credit. We differentiate through deep Wall Street expertise, strategic LP networks, and innovative financing vehicles. New York | $500K – $10M | 22 | Both | Active | ~2 mo | Open |
| 26 | ▶ Tiger Global Management Leading global companies that leverage technological innovation across public and private markets. Proven founders (especially ex-Googlers, AWS, Stripe) with large TAMs (billions+), product-led growth, and global ambitions. Conviction-based investing post-2022 correction emphasizing quality over quantity. New York | $1M – $100M | 21 | Leads | Active | ~1 wk | Req'd |
| 27 | ▶ Insight Partners Software founders need more than capital to scale successfully. Insight Partners combines investment capital with hands-on operational expertise, embedded teams, and network access to accelerate company growth across all stages. New York | $10M – $350M | 28 | Leads | Active | ~1 mo | Open |
| 28 | ▶ Gaingels Equity of access and representation in venture capital delivers positive returns. Diverse and underrepresented (including LGBTQ+) leaders of high-growth companies deserve capital access. When these founders succeed, they influence ecosystems and open doors for historically excluded groups. New York | $200K – $500K | 29 | Follows | Active | ~2 wks | Open |
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Firms that frequently co-invest with investors on this page
F4 Fund tracks 28 VC firms that actively invest in security & cybersecurity + healthcare & digital health at the Growth stage. These firms are ranked using a composite score that weighs data completeness (30%), portfolio depth (30%), investment recency (25%), and stage alignment (15%).
Based on F4's analysis, the median check size for growth security & cybersecurity + healthcare & digital health investors is $17.5M – $17.5M, with a full range from $100K – $350M. The distribution breaks down as: 1 firms in the <$500K range, 2 firms in the $2M-$5M range, 4 firms in the $5M-$10M range, 21 firms in the $10M+ range.
Among the 28 firms tracked, 93% lead or co-lead rounds, and 7% typically follow. Founders seeking a lead investor should filter for firms marked "Leads" or "Both" in the rankings table above. Lead investors typically set deal terms and anchor the round.
The best growth security & cybersecurity + healthcare & digital health investors combine domain expertise with an active portfolio in the space. Among these firms, 44% prefer warm introductions, and the average firm has 50 portfolio companies. Look for firms whose check size matches your raise, whose stage preference aligns with yours, and who have a track record of supporting companies in your sector through multiple growth phases.
Firm profiles are continuously updated through F4's research pipeline, which combines LLM-powered web research, portfolio analysis, and transcript extraction. The ranking data refreshes every 12 hours. Editorial analysis is reviewed weekly. Individual firm profiles are re-researched on a 30-day cycle or when new information surfaces.